BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 22577815)

  • 1. Function and expression of the proton-coupled amino acid transporter PAT1 along the rat gastrointestinal tract: implications for intestinal absorption of gaboxadol.
    Broberg Ml; Holm R; Tønsberg H; Frølund S; Ewon KB; Nielsen Al; Brodin B; Jensen A; Kall MA; Christensen KV; Nielsen CU
    Br J Pharmacol; 2012 Oct; 167(3):654-65. PubMed ID: 22577815
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sertraline inhibits the transport of PAT1 substrates in vivo and in vitro.
    Nielsen CU; Frølund S; Abdulhadi S; Sari H; Langthaler L; Nøhr MK; Kall MA; Brodin B; Holm R
    Br J Pharmacol; 2013 Nov; 170(5):1041-52. PubMed ID: 23962042
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intestinal gaboxadol absorption via PAT1 (SLC36A1): modified absorption in vivo following co-administration of L-tryptophan.
    Larsen M; Holm R; Jensen KG; Brodin B; Nielsen CU
    Br J Pharmacol; 2009 Aug; 157(8):1380-9. PubMed ID: 19594759
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 5-Hydroxy-L-tryptophan alters gaboxadol pharmacokinetics in rats: involvement of PAT1 and rOat1 in gaboxadol absorption and elimination.
    Larsen M; Holm R; Jensen KG; Sveigaard C; Brodin B; Nielsen CU
    Eur J Pharm Sci; 2010 Jan; 39(1-3):68-75. PubMed ID: 19900542
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rectal absorption of vigabatrin, a substrate of the proton coupled amino acid transporter (PAT1, Slc36a1), in rats.
    Holm R; Kall MA; Frølund S; Nielsen AL; Jensen A; Broberg ML; Nielsen CU
    Pharm Res; 2012 Apr; 29(4):1134-42. PubMed ID: 22234618
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Intestinal drug transport via the proton-coupled amino acid transporter PAT1 (SLC36A1) is inhibited by Gly-X(aa) dipeptides.
    Frølund S; Langthaler L; Kall MA; Holm R; Nielsen CU
    Mol Pharm; 2012 Sep; 9(9):2761-9. PubMed ID: 22853447
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1).
    Voigt V; Laug L; Zebisch K; Thondorf I; Markwardt F; Brandsch M
    J Pharm Pharmacol; 2013 Apr; 65(4):582-90. PubMed ID: 23488788
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oral and intravenous pharmacokinetics of taurine in sprague-dawley rats: the influence of dose and the possible involvement of the proton-coupled amino acid transporter, PAT1, in oral taurine absorption.
    Nielsen CU; Bjerg M; Ulaganathan N; Holm R
    Physiol Rep; 2017 Oct; 5(19):. PubMed ID: 29038364
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitory Effects of 17-α-Ethinyl-Estradiol and 17-β-Estradiol on Transport Via the Intestinal Proton-Coupled Amino Acid Transporter (PAT1) Investigated In Vitro and In Vivo.
    Nielsen CU; Pedersen M; Müller S; Kæstel T; Bjerg M; Ulaganathan N; Nielsen S; Carlsen KL; Nøhr MK; Holm R
    J Pharm Sci; 2021 Jan; 110(1):354-364. PubMed ID: 32835702
    [TBL] [Abstract][Full Text] [Related]  

  • 10. H+/amino acid transporter 1 (PAT1) is the imino acid carrier: An intestinal nutrient/drug transporter in human and rat.
    Anderson CM; Grenade DS; Boll M; Foltz M; Wake KA; Kennedy DJ; Munck LK; Miyauchi S; Taylor PM; Campbell FC; Munck BG; Daniel H; Ganapathy V; Thwaites DT
    Gastroenterology; 2004 Nov; 127(5):1410-22. PubMed ID: 15521011
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics.
    Frølund S; Holm R; Brodin B; Nielsen CU
    Br J Pharmacol; 2010 Oct; 161(3):589-600. PubMed ID: 20880398
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure, function and immunolocalization of a proton-coupled amino acid transporter (hPAT1) in the human intestinal cell line Caco-2.
    Chen Z; Fei YJ; Anderson CM; Wake KA; Miyauchi S; Huang W; Thwaites DT; Ganapathy V
    J Physiol; 2003 Jan; 546(Pt 2):349-61. PubMed ID: 12527723
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Is oral absorption of vigabatrin carrier-mediated?
    Nøhr MK; Juul RV; Thale ZI; Holm R; Kreilgaard M; Nielsen CU
    Eur J Pharm Sci; 2015 Mar; 69():10-8. PubMed ID: 25562534
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The orally active antihyperglycemic drug beta-guanidinopropionic acid is transported by the human proton-coupled amino acid transporter hPAT1.
    Metzner L; Dorn M; Markwardt F; Brandsch M
    Mol Pharm; 2009; 6(3):1006-11. PubMed ID: 19358571
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Substrate specificity and functional characterisation of the H+/amino acid transporter rat PAT2 (Slc36a2).
    Kennedy DJ; Gatfield KM; Winpenny JP; Ganapathy V; Thwaites DT
    Br J Pharmacol; 2005 Jan; 144(1):28-41. PubMed ID: 15644866
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transport of amino acids and GABA analogues via the human proton-coupled amino acid transporter, hPAT1: characterization of conditions for affinity and transport experiments in Caco-2 cells.
    Larsen M; Larsen BB; Frølund B; Nielsen CU
    Eur J Pharm Sci; 2008 Sep; 35(1-2):86-95. PubMed ID: 18621125
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Vigabatrin transport across the human intestinal epithelial (Caco-2) brush-border membrane is via the H+ -coupled amino-acid transporter hPAT1.
    Abbot EL; Grenade DS; Kennedy DJ; Gatfield KM; Thwaites DT
    Br J Pharmacol; 2006 Feb; 147(3):298-306. PubMed ID: 16331283
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Carrier-mediated γ-aminobutyric acid transport across the basolateral membrane of human intestinal Caco-2 cell monolayers.
    Nielsen CU; Carstensen M; Brodin B
    Eur J Pharm Biopharm; 2012 Jun; 81(2):458-62. PubMed ID: 22452873
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Taurine uptake across the human intestinal brush-border membrane is via two transporters: H+-coupled PAT1 (SLC36A1) and Na+- and Cl(-)-dependent TauT (SLC6A6).
    Anderson CM; Howard A; Walters JR; Ganapathy V; Thwaites DT
    J Physiol; 2009 Feb; 587(Pt 4):731-44. PubMed ID: 19074966
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Gaboxadol has affinity for the proton-coupled amino acid transporter 1, SLC36A1 (hPAT1)--A modelling approach to determine IC(50) values of the three ionic species of gaboxadol.
    Frølund S; Rapin N; Nielsen CU
    Eur J Pharm Sci; 2011 Feb; 42(3):192-8. PubMed ID: 21112392
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.