188 related articles for article (PubMed ID: 22578459)
1. Structure and property based design, synthesis and biological evaluation of γ-lactam based HDAC inhibitors: part II.
Lee C; Choi E; Cho M; Lee B; Oh SJ; Park SK; Lee K; Kim HM; Han G
Bioorg Med Chem Lett; 2012 Jun; 22(12):4189-92. PubMed ID: 22578459
[TBL] [Abstract][Full Text] [Related]
2. Structure and property based design, synthesis and biological evaluation of γ-lactam based HDAC inhibitors.
Choi E; Lee C; Park JE; Seo JJ; Cho M; Kang JS; Kim HM; Park SK; Lee K; Han G
Bioorg Med Chem Lett; 2011 Feb; 21(4):1218-21. PubMed ID: 21256006
[TBL] [Abstract][Full Text] [Related]
3. Modification of cap group in delta-lactam-based histone deacetylase (HDAC) inhibitors.
Kim HM; Hong SH; Kim MS; Lee CW; Kang JS; Lee K; Park SK; Han JW; Lee HY; Choi Y; Kwon HJ; Han G
Bioorg Med Chem Lett; 2007 Nov; 17(22):6234-8. PubMed ID: 17904843
[TBL] [Abstract][Full Text] [Related]
4. Lactam-based HDAC inhibitors for anticancer chemotherapy: restoration of RUNX3 by posttranslational modification and epigenetic control.
Cho M; Choi E; Kim JH; Kim H; Kim HM; Lee JI; Hwang KC; Kim HJ; Han G
ChemMedChem; 2014 Mar; 9(3):649-56. PubMed ID: 24376239
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and preliminary bioactivity studies of 1,3,4-thiadiazole hydroxamic acid derivatives as novel histone deacetylase inhibitors.
Guan P; Sun F; Hou X; Wang F; Yi F; Xu W; Fang H
Bioorg Med Chem; 2012 Jun; 20(12):3865-72. PubMed ID: 22579621
[TBL] [Abstract][Full Text] [Related]
6. Amide-based derivatives of β-alanine hydroxamic acid as histone deacetylase inhibitors: attenuation of potency through resonance effects.
Liao V; Liu T; Codd R
Bioorg Med Chem Lett; 2012 Oct; 22(19):6200-4. PubMed ID: 22932316
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological characterization of amidopropenyl hydroxamates as HDAC inhibitors.
Thaler F; Varasi M; Colombo A; Boggio R; Munari D; Regalia N; Rozio MG; Reali V; Resconi AE; Mai A; Gagliardi S; Dondio G; Minucci S; Mercurio C
ChemMedChem; 2010 Aug; 5(8):1359-72. PubMed ID: 20572281
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and anticancer activity of piperazine hydroxamates and their histone deacetylase (HDAC) inhibitory activity.
Chetan B; Bunha M; Jagrat M; Sinha BN; Saiko P; Graser G; Szekeres T; Raman G; Rajendran P; Moorthy D; Basu A; Jayaprakash V
Bioorg Med Chem Lett; 2010 Jul; 20(13):3906-10. PubMed ID: 20605448
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis and preliminary activity assay of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as novel Histone deacetylases (HDACs) inhibitors.
Zhang Y; Feng J; Liu C; Zhang L; Jiao J; Fang H; Su L; Zhang X; Zhang J; Li M; Wang B; Xu W
Bioorg Med Chem; 2010 Mar; 18(5):1761-72. PubMed ID: 20171895
[TBL] [Abstract][Full Text] [Related]
10. Property based optimization of δ-lactam HDAC inhibitors for metabolic stability.
Yoon HC; Choi E; Park JE; Cho M; Seo JJ; Oh SJ; Kang JS; Kim HM; Park SK; Lee K; Han G
Bioorg Med Chem Lett; 2010 Nov; 20(22):6808-11. PubMed ID: 20850971
[TBL] [Abstract][Full Text] [Related]
11. Structure-activity relationship studies of a series of novel delta-lactam-based histone deacetylase inhibitors.
Kim HM; Ryu DK; Choi Y; Park BW; Lee K; Han SB; Lee CW; Kang MR; Kang JS; Boovanahalli SK; Park SK; Han JW; Chun TG; Lee HY; Nam KY; Choi EH; Han G
J Med Chem; 2007 May; 50(11):2737-41. PubMed ID: 17477518
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and antitumor activity of novel diaryl ether hydroxamic acids derivatives as potential HDAC inhibitors.
Zhu Y; Chen X; Wu Z; Zheng Y; Chen Y; Tang W; Lu T
Arch Pharm Res; 2012 Oct; 35(10):1723-32. PubMed ID: 23139122
[TBL] [Abstract][Full Text] [Related]
13. Improved antiproliferative activity of 1,3,4-thiadiazole-containing histone deacetylase (HDAC) inhibitors by introduction of the heteroaromatic surface recognition motif.
Guan P; Wang L; Hou X; Wan Y; Xu W; Tang W; Fang H
Bioorg Med Chem; 2014 Nov; 22(21):5766-75. PubMed ID: 25311567
[TBL] [Abstract][Full Text] [Related]
14. Novel inhibitors of human histone deacetylases: design, synthesis and bioactivity of 3-alkenoylcoumarines.
Seidel C; Schnekenburger M; Zwergel C; Gaascht F; Mai A; Dicato M; Kirsch G; Valente S; Diederich M
Bioorg Med Chem Lett; 2014 Aug; 24(16):3797-801. PubMed ID: 25042254
[TBL] [Abstract][Full Text] [Related]
15. New aryldithiolethione derivatives as potent histone deacetylase inhibitors.
Tazzari V; Cappelletti G; Casagrande M; Perrino E; Renzi L; Del Soldato P; Sparatore A
Bioorg Med Chem; 2010 Jun; 18(12):4187-94. PubMed ID: 20576572
[TBL] [Abstract][Full Text] [Related]
16. Structure-based optimization of click-based histone deacetylase inhibitors.
Hou J; Feng C; Li Z; Fang Q; Wang H; Gu G; Shi Y; Liu P; Xu F; Yin Z; Shen J; Wang P
Eur J Med Chem; 2011 Aug; 46(8):3190-200. PubMed ID: 21621883
[TBL] [Abstract][Full Text] [Related]
17. Design and synthesis of novel isoxazole-based HDAC inhibitors.
Conti P; Tamborini L; Pinto A; Sola L; Ettari R; Mercurio C; De Micheli C
Eur J Med Chem; 2010 Sep; 45(9):4331-8. PubMed ID: 20637529
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222.
Terracciano S; Di Micco S; Bifulco G; Gallinari P; Riccio R; Bruno I
Bioorg Med Chem; 2010 May; 18(9):3252-60. PubMed ID: 20381359
[TBL] [Abstract][Full Text] [Related]
19. Identification of a series of substituted 2-piperazinyl-5-pyrimidylhydroxamic acids as potent histone deacetylase inhibitors.
Angibaud P; Van Emelen K; Decrane L; van Brandt S; Ten Holte P; Pilatte I; Roux B; Poncelet V; Speybrouck D; Queguiner L; Gaurrand S; Mariën A; Floren W; Janssen L; Verdonck M; van Dun J; van Gompel J; Gilissen R; Mackie C; Du Jardin M; Peeters J; Noppe M; Van Hijfte L; Freyne E; Page M; Janicot M; Arts J
Bioorg Med Chem Lett; 2010 Jan; 20(1):294-8. PubMed ID: 19906529
[TBL] [Abstract][Full Text] [Related]
20. Discovery of pyridone-based histone deacetylase inhibitors: approaches for metabolic stability.
Cho M; Choi E; Yang JS; Lee C; Seo JJ; Kim BS; Oh SJ; Kim HM; Lee K; Park SK; Kwon HJ; Han G
ChemMedChem; 2013 Feb; 8(2):272-9. PubMed ID: 23292995
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
