These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 22578461)

  • 1. Synthesis and characterization of 2'-C-Me branched C-nucleosides as HCV polymerase inhibitors.
    Cho A; Zhang L; Xu J; Babusis D; Butler T; Lee R; Saunders OL; Wang T; Parrish J; Perry J; Feng JY; Ray AS; Kim CU
    Bioorg Med Chem Lett; 2012 Jun; 22(12):4127-32. PubMed ID: 22578461
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Preparation and biological evaluation of 1'-cyano-2'-C-methyl pyrimidine nucleosides as HCV NS5B polymerase inhibitors.
    Mish MR; Cho A; Kirschberg T; Xu J; Zonte CS; Fenaux M; Park Y; Babusis D; Feng JY; Ray AS; Kim CU
    Bioorg Med Chem Lett; 2014 Jul; 24(14):3092-5. PubMed ID: 24907145
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and antiviral activity of a series of 1'-substituted 4-aza-7,9-dideazaadenosine C-nucleosides.
    Cho A; Saunders OL; Butler T; Zhang L; Xu J; Vela JE; Feng JY; Ray AS; Kim CU
    Bioorg Med Chem Lett; 2012 Apr; 22(8):2705-7. PubMed ID: 22446091
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of 3'-C-hydroxymethyl-substituted pyrimidine and purine nucleosides as potential anti-hepatitis C virus (HCV) agents.
    Pei X; Choi WJ; Kim YM; Zhao LX; Jeong LS
    Arch Pharm Res; 2008 Jul; 31(7):843-9. PubMed ID: 18704325
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and anti-hepatitis C virus (HCV) activity of 3'-C-substituted-methyl pyrimidine and purine nucleosides.
    Choi WJ; Kim YM; Kim HO; Lee HW; Kim DE; Park KS; Chong Y; Jeong LS
    Bioorg Med Chem; 2010 Jul; 18(13):4812-20. PubMed ID: 20627592
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and antiviral evaluation of 4'-C-azidomethyl-beta-D-ribofuranosyl purine and pyrimidine nucleosides.
    Griffon JF; Dumas A; Storer R; Sommadossi JP; Gosselin G
    Nucleosides Nucleotides Nucleic Acids; 2009 May; 28(5):435-49. PubMed ID: 20183594
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and antiviral properties of novel tetracyclic nucleoside inhibitors of hepatitis C NS5B polymerase.
    Di Francesco ME; Avolio S; Dessole G; Koch U; Pompei M; Pucci V; Rowley M; Summa V
    Nucleosides Nucleotides Nucleic Acids; 2012; 31(8):592-607. PubMed ID: 22908950
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nucleoside analog inhibitors of hepatitis C virus replication.
    Carroll SS; Olsen DB
    Infect Disord Drug Targets; 2006 Mar; 6(1):17-29. PubMed ID: 16787301
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of pyrrolo[2,3-d]pyrimidine nucleoside derivatives as potential anti-HCV agents.
    Varaprasad CV; Ramasamy KS; Girardet JL; Gunic E; Lai V; Zhong W; An H; Hong Z
    Bioorg Chem; 2007 Feb; 35(1):25-34. PubMed ID: 16945403
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors.
    Barnes-Seeman D; Boiselle C; Capacci-Daniel C; Chopra R; Hoffmaster K; Jones CT; Kato M; Lin K; Ma S; Pan G; Shu L; Wang J; Whiteman L; Xu M; Zheng R; Fu J
    Bioorg Med Chem Lett; 2014 Aug; 24(16):3979-85. PubMed ID: 24986660
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of novel carbocyclic nucleosides with a modified cyclopentane ring and evaluation of their antiviral activity.
    Nieto I; Figueira MJ; Blanco JM; Caamaño O; Fernández F; De Clercq E; Balzarini J
    Nucleosides Nucleotides; 1999; 18(4-5):641-2. PubMed ID: 10432656
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 2'-deoxy-4'-azido nucleoside analogs are highly potent inhibitors of hepatitis C virus replication despite the lack of 2'-alpha-hydroxyl groups.
    Klumpp K; Kalayanov G; Ma H; Le Pogam S; Leveque V; Jiang WR; Inocencio N; De Witte A; Rajyaguru S; Tai E; Chanda S; Irwin MR; Sund C; Winqist A; Maltseva T; Eriksson S; Usova E; Smith M; Alker A; Najera I; Cammack N; Martin JA; Johansson NG; Smith DB
    J Biol Chem; 2008 Jan; 283(4):2167-75. PubMed ID: 18003608
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of purine modified 2'-C-methyl nucleosides as potential anti-HCV agents.
    Zhang HW; Zhou L; Coats SJ; McBrayer TR; Tharnish PM; Bondada L; Detorio M; Amichai SA; Johns MD; Whitaker T; Schinazi RF
    Bioorg Med Chem Lett; 2011 Nov; 21(22):6788-92. PubMed ID: 21983447
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The novel unsaturated acyclic nucleoside analogues: cytostatic and antiviral activity evaluations.
    Wittine K; Benci K; Pavelić SK; Pavelić K; Mintas M
    Nucleic Acids Symp Ser (Oxf); 2008; (52):601-2. PubMed ID: 18776523
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymerase.
    Zheng BZ; D'Andrea SV; Hanumegowda U; Knipe JO; Mosure K; Zhuo X; Lemm JA; Liu M; Rigat KL; Wang YK; Fang H; Poronsky C; Cutrone J; Wu DR; Arunachalam PN; Balapragalathan TJ; Arumugam A; Mathur A; Meanwell NA; Gao M; Roberts SB; Kadow JF
    Bioorg Med Chem Lett; 2017 Aug; 27(15):3294-3300. PubMed ID: 28633899
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and characterization of 1'-C-cyano-2'-fluoro-2'-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors.
    Kirschberg TA; Mish MR; Zhang L; Squires NH; Wang KY; Cho A; Feng JY; Fenaux M; Babusis D; Park Y; Ray AS; Kim CU
    Bioorg Med Chem Lett; 2015 Mar; 25(5):1040-3. PubMed ID: 25650256
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of 2'-fluoro and 2',4'-dimethyl pyrimidine C-nucleoside analogues as potential anti-HCV agents.
    Liu LJ; Hong JH
    Nucleosides Nucleotides Nucleic Acids; 2010 Mar; 29(3):216-27. PubMed ID: 20408052
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and anti-HCV activity of a new 2'-deoxy-2'-fluoro-2'-C-methyl nucleoside analogue.
    Hu W; Wang P; Song C; Pan Z; Wang Q; Guo X; Yu X; Shen Z; Wang S; Chang J
    Bioorg Med Chem Lett; 2010 Dec; 20(24):7297-8. PubMed ID: 21106452
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase.
    Eldrup AB; Allerson CR; Bennett CF; Bera S; Bhat B; Bhat N; Bosserman MR; Brooks J; Burlein C; Carroll SS; Cook PD; Getty KL; MacCoss M; McMasters DR; Olsen DB; Prakash TP; Prhavc M; Song Q; Tomassini JE; Xia J
    J Med Chem; 2004 Apr; 47(9):2283-95. PubMed ID: 15084127
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Current perspective of HCV NS5B inhibitors: a review.
    Patil VM; Gupta SP; Samanta S; Masand N
    Curr Med Chem; 2011; 18(36):5564-97. PubMed ID: 22172066
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.