These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 22579486)

  • 1. Acylprolinamides: a new class of peptide deformylase inhibitors with in vivo antibacterial activity.
    Axten JM; Medina JR; Blackledge CW; Duquenne C; Grant SW; Bobko MA; Peng T; Miller WH; Pinckney T; Gallagher TF; Kulkarni S; Lewandowski T; Van Aller GS; Zonis R; Ward P; Campobasso N
    Bioorg Med Chem Lett; 2012 Jun; 22(12):4028-32. PubMed ID: 22579486
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Peptide deformylase inhibitors with retro-amide scaffold: synthesis and structure-activity relationships.
    Lee SK; Choi KH; Lee SJ; Suh SW; Kim BM; Lee BJ
    Bioorg Med Chem Lett; 2010 Aug; 20(15):4317-9. PubMed ID: 20615695
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of piperazic acid peptide deformylase inhibitors with in vivo activity for respiratory tract and skin infections.
    Spletstoser JT; Dreabit J; Knox AN; Benowitz A; Campobasso N; Ward P; Cui G; Lewandowski T; McCloskey L; Aubart KM
    Bioorg Med Chem Lett; 2019 Aug; 29(16):2410-2414. PubMed ID: 31160176
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors.
    Lee SJ; Lee SJ; Lee SK; Yoon HJ; Lee HH; Kim KK; Lee BJ; Lee BI; Suh SW
    Acta Crystallogr D Biol Crystallogr; 2012 Jul; 68(Pt 7):784-93. PubMed ID: 22751663
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacokinetics/Pharmacodynamics of Peptide Deformylase Inhibitor GSK1322322 against Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus in Rodent Models of Infection.
    Hoover J; Lewandowski T; Straub RJ; Novick SJ; DeMarsh P; Aubart K; Rittenhouse S; Zalacain M
    Antimicrob Agents Chemother; 2016 Jan; 60(1):180-9. PubMed ID: 26482300
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Peptidomimetic inhibitors of bacterial peptide deformylase.
    East SP; Ayscough A; Toogood-Johnson I; Taylor S; Thomas W
    Bioorg Med Chem Lett; 2011 Jul; 21(13):4032-5. PubMed ID: 21621999
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Peptide deformylase inhibitors with activity against respiratory tract pathogens.
    East SP; Beckett RP; Brookings DC; Clements JM; Doel S; Keavey K; Pain G; Smith HK; Thomas W; Thompson AJ; Todd RS; Whittaker M
    Bioorg Med Chem Lett; 2004 Jan; 14(1):59-62. PubMed ID: 14684298
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antimicrobial activity of a novel peptide deformylase inhibitor, LBM415, tested against respiratory tract and cutaneous infection pathogens: a global surveillance report (2003-2004).
    Watters AA; Jones RN; Leeds JA; Denys G; Sader HS; Fritsche TR
    J Antimicrob Chemother; 2006 May; 57(5):914-23. PubMed ID: 16549511
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antimicrobial activity of the new macrolide flurithromycin against Haemophilus influenzae, Streptococcus pneumoniae, Streptococcus pyogenes, Branhamella catarrhalis and Staphylococcus aureus.
    Nord CE; Lindmark A; Persson I
    J Chemother; 1989 Jul; 1(4 Suppl):203-4. PubMed ID: 16312369
    [No Abstract]   [Full Text] [Related]  

  • 10. Synthesis and in vitro antibacterial activity of (2S)-N-(substitutedphenyl)-1-[(2R)-2-[(formylhydroxyamino)methyl]-1-oxohexyl]-2-pyrrolidinecarboxamides as potential peptide deformylase inhibitors.
    Wang Z; Zhou W
    Chem Biol Drug Des; 2009 Jan; 73(1):142-6. PubMed ID: 19152643
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Indole naphthyridinones as inhibitors of bacterial enoyl-ACP reductases FabI and FabK.
    Seefeld MA; Miller WH; Newlander KA; Burgess WJ; DeWolf WE; Elkins PA; Head MS; Jakas DR; Janson CA; Keller PM; Manley PJ; Moore TD; Payne DJ; Pearson S; Polizzi BJ; Qiu X; Rittenhouse SF; Uzinskas IN; Wallis NG; Huffman WF
    J Med Chem; 2003 Apr; 46(9):1627-35. PubMed ID: 12699381
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens.
    Agouridas C; Denis A; Auger JM; Benedetti Y; Bonnefoy A; Bretin F; Chantot JF; Dussarat A; Fromentin C; D'Ambrières SG; Lachaud S; Laurin P; Le Martret O; Loyau V; Tessot N
    J Med Chem; 1998 Oct; 41(21):4080-100. PubMed ID: 9767644
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, activity and pharmacokinetics of novel antibacterial 15-membered ring macrolones.
    Fajdetić A; Vinter A; Paljetak HČ; Padovan J; Jakopović IP; Kapić S; Alihodžić S; Filić D; Modrić M; Košutić-Hulita N; Antolović R; Schoenfeld ZI; Mutak S; Eraković Haber V; Spaventi R
    Eur J Med Chem; 2011 Aug; 46(8):3388-97. PubMed ID: 21600677
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents.
    Apfel C; Banner DW; Bur D; Dietz M; Hirata T; Hubschwerlen C; Locher H; Page MG; Pirson W; Rossé G; Specklin JL
    J Med Chem; 2000 Jun; 43(12):2324-31. PubMed ID: 10882358
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and antibacterial activity of 3-methylenepyrrolidine formyl hydroxyamino derivatives as novel peptide deformylase inhibitors.
    Shi W; Ma H; Duan Y; Aubart K; Fang Y; Zonis R; Yang L; Hu W
    Bioorg Med Chem Lett; 2011 Feb; 21(3):1060-3. PubMed ID: 21185180
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, antibacterial activity, and biological evaluation of formyl hydroxyamino derivatives as novel potent peptide deformylase inhibitors against drug-resistant bacteria.
    Yang S; Shi W; Xing D; Zhao Z; Lv F; Yang L; Yang Y; Hu W
    Eur J Med Chem; 2014 Oct; 86():133-52. PubMed ID: 25151577
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.
    Gross M; Clements J; Beckett RP; Thomas W; Taylor S; Lofland D; Ramanathan-Girish S; Garcia M; Difuntorum S; Hoch U; Chen H; Johnson KW
    J Antimicrob Chemother; 2004 Mar; 53(3):487-93. PubMed ID: 14963065
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Macrocyclic inhibitors for peptide deformylase: a structure-activity relationship study of the ring size.
    Hu X; Nguyen KT; Jiang VC; Lofland D; Moser HE; Pei D
    J Med Chem; 2004 Sep; 47(20):4941-9. PubMed ID: 15369398
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Peptide deformylase inhibitors with non-peptide scaffold: synthesis and structure-activity relationships.
    Lee SK; Choi KH; Lee SJ; Lee JS; Park JY; Kim BM; Lee BJ
    Bioorg Med Chem Lett; 2011 Jan; 21(1):133-6. PubMed ID: 21146987
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 15-amido erythromycins: synthesis and in vitro activity of a new class of macrolide antibiotics.
    Shaw SJ; Abbanat D; Ashley GW; Bush K; Foleno B; Macielag M; Zhang D; Myles DC
    J Antibiot (Tokyo); 2005 Mar; 58(3):167-77. PubMed ID: 15895524
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.