254 related articles for article (PubMed ID: 22579620)
1. Inhibition of thioredoxin reductase by a novel series of bis-1,2-benzisoselenazol-3(2H)-ones: Organoselenium compounds for cancer therapy.
He J; Li D; Xiong K; Ge Y; Jin H; Zhang G; Hong M; Tian Y; Yin J; Zeng H
Bioorg Med Chem; 2012 Jun; 20(12):3816-27. PubMed ID: 22579620
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and evaluation of curcumin analogues as potential thioredoxin reductase inhibitors.
Qiu X; Liu Z; Shao WY; Liu X; Jing DP; Yu YJ; An LK; Huang SL; Bu XZ; Huang ZS; Gu LQ
Bioorg Med Chem; 2008 Sep; 16(17):8035-41. PubMed ID: 18678491
[TBL] [Abstract][Full Text] [Related]
3. Diaryl chalcogenides as selective inhibitors of thioredoxin reductase and potential antitumor agents.
Engman L; Cotgreave I; Angulo M; Taylor CW; Paine-Murrieta GD; Powis G
Anticancer Res; 1997; 17(6D):4599-605. PubMed ID: 9494575
[TBL] [Abstract][Full Text] [Related]
4. Selenadiazole derivatives as potent thioredoxin reductase inhibitors that enhance the radiosensitivity of cancer cells.
Liang YW; Zheng J; Li X; Zheng W; Chen T
Eur J Med Chem; 2014 Sep; 84():335-42. PubMed ID: 25036792
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, SAR and biological evaluation of a novel series of 1-(2-chloroethyl)-1-nitroso-3-(2-(3-oxobenzoelenazol-2(3H)-yl)ethyl) urea: Organoselenium compounds for cancer therapy.
Ye S; Zheng X; Hu T; Zeng H
Cell Mol Biol (Noisy-le-grand); 2016 Jun; 62(7):6-14. PubMed ID: 27453265
[TBL] [Abstract][Full Text] [Related]
6. Thioredoxin reductase inhibition by antitumor quinols: a quinol pharmacophore effect correlating to antiproliferative activity.
Chew EH; Lu J; Bradshaw TD; Holmgren A
FASEB J; 2008 Jun; 22(6):2072-83. PubMed ID: 18180330
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of both thioredoxin reductase and glutathione reductase may contribute to the anticancer mechanism of TH-302.
Li S; Zhang J; Li J; Chen D; Matteucci M; Curd J; Duan JX
Biol Trace Elem Res; 2010 Sep; 136(3):294-301. PubMed ID: 19838642
[TBL] [Abstract][Full Text] [Related]
8. Small molecule inhibitors of mammalian thioredoxin reductase.
Cai W; Zhang L; Song Y; Wang B; Zhang B; Cui X; Hu G; Liu Y; Wu J; Fang J
Free Radic Biol Med; 2012 Jan; 52(2):257-65. PubMed ID: 22064364
[TBL] [Abstract][Full Text] [Related]
9. A thioredoxin reductase inhibitor induces growth inhibition and apoptosis in five cultured human carcinoma cell lines.
Zhao F; Yan J; Deng S; Lan L; He F; Kuang B; Zeng H
Cancer Lett; 2006 May; 236(1):46-53. PubMed ID: 15982805
[TBL] [Abstract][Full Text] [Related]
10. Applying the designed multiple ligands approach to inhibit dihydrofolate reductase and thioredoxin reductase for anti-proliferative activity.
Ng HL; Chen S; Chew EH; Chui WK
Eur J Med Chem; 2016 Jun; 115():63-74. PubMed ID: 26994844
[TBL] [Abstract][Full Text] [Related]
11. Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds.
Casini A; Gabbiani C; Sorrentino F; Rigobello MP; Bindoli A; Geldbach TJ; Marrone A; Re N; Hartinger CG; Dyson PJ; Messori L
J Med Chem; 2008 Nov; 51(21):6773-81. PubMed ID: 18834187
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of thioredoxin reductase by mansonone F analogues: Implications for anticancer activity.
Liu Z; Huang SL; Li MM; Huang ZS; Lee KS; Gu LQ
Chem Biol Interact; 2009 Jan; 177(1):48-57. PubMed ID: 18822278
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds.
Witte AB; Anestål K; Jerremalm E; Ehrsson H; Arnér ES
Free Radic Biol Med; 2005 Sep; 39(5):696-703. PubMed ID: 16085187
[TBL] [Abstract][Full Text] [Related]
14. 3-Nitro-2H-chromenes as a new class of inhibitors against thioredoxin reductase and proliferation of cancer cells.
Xiao GQ; Liang BX; Chen SH; Ou TM; Bu XZ; Yan M
Arch Pharm (Weinheim); 2012 Oct; 345(10):767-70. PubMed ID: 22836584
[TBL] [Abstract][Full Text] [Related]
15. Dithiaarsanes induce oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase.
Liu Y; Duan D; Yao J; Zhang B; Peng S; Ma H; Song Y; Fang J
J Med Chem; 2014 Jun; 57(12):5203-11. PubMed ID: 24867309
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and in vitro anticancer activity of 6,7-methylenedioxy (or 5-hydroxy-6-methoxy)-2-(substituted selenophenyl)quinolin-4-one analogs.
Chen CT; Hsu MH; Cheng YY; Liu CY; Chou LC; Huang LJ; Wu TS; Yang X; Lee KH; Kuo SC
Eur J Med Chem; 2011 Dec; 46(12):6046-56. PubMed ID: 22030314
[TBL] [Abstract][Full Text] [Related]
17. Natural product based inhibitors of the thioredoxin-thioredoxin reductase system.
Wipf P; Lynch SM; Birmingham A; Tamayo G; Jiménez A; Campos N; Powis G
Org Biomol Chem; 2004 Jun; 2(11):1651-8. PubMed ID: 15162219
[TBL] [Abstract][Full Text] [Related]
18. Benzimidazol-2-ylidene gold(I) complexes are thioredoxin reductase inhibitors with multiple antitumor properties.
Rubbiani R; Kitanovic I; Alborzinia H; Can S; Kitanovic A; Onambele LA; Stefanopoulou M; Geldmacher Y; Sheldrick WS; Wolber G; Prokop A; Wölfl S; Ott I
J Med Chem; 2010 Dec; 53(24):8608-18. PubMed ID: 21082862
[TBL] [Abstract][Full Text] [Related]
19. NHC gold halide complexes derived from 4,5-diarylimidazoles: synthesis, structural analysis, and pharmacological investigations as potential antitumor agents.
Liu W; Bensdorf K; Proetto M; Abram U; Hagenbach A; Gust R
J Med Chem; 2011 Dec; 54(24):8605-15. PubMed ID: 22091836
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of bacterial thioredoxin reductase: an antibiotic mechanism targeting bacteria lacking glutathione.
Lu J; Vlamis-Gardikas A; Kandasamy K; Zhao R; Gustafsson TN; Engstrand L; Hoffner S; Engman L; Holmgren A
FASEB J; 2013 Apr; 27(4):1394-403. PubMed ID: 23248236
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
