246 related articles for article (PubMed ID: 22580100)
21. Expression, purification and crystallization of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with orotate.
Inaoka DK; Takashima E; Osanai A; Shimizu H; Nara T; Aoki T; Harada S; Kita K
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2005 Oct; 61(Pt 10):875-8. PubMed ID: 16511183
[TBL] [Abstract][Full Text] [Related]
22. Identification of 3,4-Dihydro-2
Hartuti ED; Sakura T; Tagod MSO; Yoshida E; Wang X; Mochizuki K; Acharjee R; Matsuo Y; Tokumasu F; Mori M; Waluyo D; Shiomi K; Nozaki T; Hamano S; Shiba T; Kita K; Inaoka DK
Int J Mol Sci; 2021 Jul; 22(13):. PubMed ID: 34281290
[No Abstract] [Full Text] [Related]
23. Purification, characterization and localization of mitochondrial dihydroorotate dehydrogenase in Plasmodium falciparum, human malaria parasite.
Krungkrai J
Biochim Biophys Acta; 1995 Apr; 1243(3):351-60. PubMed ID: 7727509
[TBL] [Abstract][Full Text] [Related]
24.
Zhao E; Jiang X; Cui H
Int J Mol Sci; 2018 Aug; 19(9):. PubMed ID: 30200251
[TBL] [Abstract][Full Text] [Related]
25. Catalytic properties of dihydroorotate dehydrogenase from Saccharomyces cerevisiae: studies on pH, alternate substrates, and inhibitors.
Jordan DB; Bisaha JJ; Picollelli MA
Arch Biochem Biophys; 2000 Jun; 378(1):84-92. PubMed ID: 10871048
[TBL] [Abstract][Full Text] [Related]
26. Lys-D48 is required for charge stabilization, rapid flavin reduction, and internal electron transfer in the catalytic cycle of dihydroorotate dehydrogenase B of Lactococcus lactis.
Combe JP; Basran J; Hothi P; Leys D; Rigby SE; Munro AW; Scrutton NS
J Biol Chem; 2006 Jun; 281(26):17977-88. PubMed ID: 16624811
[TBL] [Abstract][Full Text] [Related]
27. Cloning, expression, purification, and characterization of Leishmania major dihydroorotate dehydrogenase.
Feliciano PR; Cordeiro AT; Costa-Filho AJ; Nonato MC
Protein Expr Purif; 2006 Jul; 48(1):98-103. PubMed ID: 16600626
[TBL] [Abstract][Full Text] [Related]
28. The structures of human dihydroorotate dehydrogenase with and without inhibitor reveal conformational flexibility in the inhibitor and substrate binding sites.
Walse B; Dufe VT; Svensson B; Fritzson I; Dahlberg L; Khairoullina A; Wellmar U; Al-Karadaghi S
Biochemistry; 2008 Aug; 47(34):8929-36. PubMed ID: 18672895
[TBL] [Abstract][Full Text] [Related]
29. Dihydroorotate dehydrogenase inhibitors in anti-infective drug research.
Boschi D; Pippione AC; Sainas S; Lolli ML
Eur J Med Chem; 2019 Dec; 183():111681. PubMed ID: 31557612
[TBL] [Abstract][Full Text] [Related]
30. Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase from Y strain.
Pinheiro MP; Iulek J; Cristina Nonato M
Biochem Biophys Res Commun; 2008 May; 369(3):812-7. PubMed ID: 18302934
[TBL] [Abstract][Full Text] [Related]
31. Active site of dihydroorotate dehydrogenase A from Lactococcus lactis investigated by chemical modification and mutagenesis.
Björnberg O; Rowland P; Larsen S; Jensen KF
Biochemistry; 1997 Dec; 36(51):16197-205. PubMed ID: 9405053
[TBL] [Abstract][Full Text] [Related]
32. Cloning and expression of the dihydroorotate dehydrogenase from Toxoplasma gondii.
Sierra Pagan ML; Zimmermann BH
Biochim Biophys Acta; 2003 Mar; 1637(2):178-81. PubMed ID: 12633907
[TBL] [Abstract][Full Text] [Related]
33. Antimalarial activity of orotate analogs that inhibit dihydroorotase and dihydroorotate dehydrogenase.
Krungkrai J; Krungkrai SR; Phakanont K
Biochem Pharmacol; 1992 Mar; 43(6):1295-301. PubMed ID: 1348618
[TBL] [Abstract][Full Text] [Related]
34. A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria.
Phillips MA; White KL; Kokkonda S; Deng X; White J; El Mazouni F; Marsh K; Tomchick DR; Manjalanagara K; Rudra KR; Wirjanata G; Noviyanti R; Price RN; Marfurt J; Shackleford DM; Chiu FC; Campbell M; Jimenez-Diaz MB; Bazaga SF; Angulo-Barturen I; Martinez MS; Lafuente-Monasterio M; Kaminsky W; Silue K; Zeeman AM; Kocken C; Leroy D; Blasco B; Rossignol E; Rueckle T; Matthews D; Burrows JN; Waterson D; Palmer MJ; Rathod PK; Charman SA
ACS Infect Dis; 2016 Dec; 2(12):945-957. PubMed ID: 27641613
[TBL] [Abstract][Full Text] [Related]
35. Variation among Plasmodium falciparum strains in their reliance on mitochondrial electron transport chain function.
Ke H; Morrisey JM; Ganesan SM; Painter HJ; Mather MW; Vaidya AB
Eukaryot Cell; 2011 Aug; 10(8):1053-61. PubMed ID: 21685321
[TBL] [Abstract][Full Text] [Related]
36. Roles in binding and chemistry for conserved active site residues in the class 2 dihydroorotate dehydrogenase from Escherichia coli.
Fagan RL; Palfey BA
Biochemistry; 2009 Aug; 48(30):7169-78. PubMed ID: 19530672
[TBL] [Abstract][Full Text] [Related]
37. Characterization of the dihydroorotate dehydrogenase as a soluble fumarate reductase in Trypanosoma cruzi.
Takashima E; Inaoka DK; Osanai A; Nara T; Odaka M; Aoki T; Inaka K; Harada S; Kita K
Mol Biochem Parasitol; 2002 Jul; 122(2):189-200. PubMed ID: 12106873
[TBL] [Abstract][Full Text] [Related]
38. Cytotoxic effects of inhibitors of de novo pyrimidine biosynthesis upon Plasmodium falciparum.
Seymour KK; Lyons SD; Phillips L; Rieckmann KH; Christopherson RI
Biochemistry; 1994 May; 33(17):5268-74. PubMed ID: 7909690
[TBL] [Abstract][Full Text] [Related]
39. Evaluation of 7-arylaminopyrazolo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors.
Azeredo LFSP; Coutinho JP; Jabor VAP; Feliciano PR; Nonato MC; Kaiser CR; Menezes CMS; Hammes ASO; Caffarena ER; Hoelz LVB; de Souza NB; Pereira GAN; Cerávolo IP; Krettli AU; Boechat N
Eur J Med Chem; 2017 Jan; 126():72-83. PubMed ID: 27744189
[TBL] [Abstract][Full Text] [Related]
40. Substrate binding and reactivity are not linked: grafting a proton-transfer network into a Class 1A dihydroorotate dehydrogenase.
McDonald CA; Palfey BA
Biochemistry; 2011 Apr; 50(14):2714-6. PubMed ID: 21401078
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]