BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 22582113)

  • 1. Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension.
    Anwar A; Li M; Frid MG; Kumar B; Gerasimovskaya EV; Riddle SR; McKeon BA; Thukaram R; Meyrick BO; Fini MA; Stenmark KR
    Am J Physiol Lung Cell Mol Physiol; 2012 Jul; 303(1):L1-L11. PubMed ID: 22582113
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Osteopontin plays important roles in pulmonary arterial hypertension induced by systemic-to-pulmonary shunt.
    Meng L; Liu X; Teng X; Gu H; Yuan W; Meng J; Li J; Zheng Z; Wei Y; Hu S
    FASEB J; 2019 Jun; 33(6):7236-7251. PubMed ID: 30893567
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Low-dose fluvastatin reverses the hypoxic pulmonary adventitial fibroblast phenotype in experimental pulmonary hypertension.
    Carlin CM; Celnik DF; Pak O; Wadsworth R; Peacock AJ; Welsh DJ
    Am J Respir Cell Mol Biol; 2012 Aug; 47(2):140-8. PubMed ID: 22383583
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1.
    Li M; Riddle S; Zhang H; D'Alessandro A; Flockton A; Serkova NJ; Hansen KC; Moldovan R; McKeon BA; Frid M; Kumar S; Li H; Liu H; Caánovas A; Medrano JF; Thomas MG; Iloska D; Plecitá-Hlavatá L; Ježek P; Pullamsetti S; Fini MA; El Kasmi KC; Zhang Q; Stenmark KR
    Circulation; 2016 Oct; 134(15):1105-1121. PubMed ID: 27562971
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.
    Zhang H; Wang D; Li M; Plecitá-Hlavatá L; D'Alessandro A; Tauber J; Riddle S; Kumar S; Flockton A; McKeon BA; Frid MG; Reisz JA; Caruso P; El Kasmi KC; Ježek P; Morrell NW; Hu CJ; Stenmark KR
    Circulation; 2017 Dec; 136(25):2468-2485. PubMed ID: 28972001
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension.
    Li M; Riddle SR; Frid MG; El Kasmi KC; McKinsey TA; Sokol RJ; Strassheim D; Meyrick B; Yeager ME; Flockton AR; McKeon BA; Lemon DD; Horn TR; Anwar A; Barajas C; Stenmark KR
    J Immunol; 2011 Sep; 187(5):2711-22. PubMed ID: 21813768
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Constitutive Reprogramming of Fibroblast Mitochondrial Metabolism in Pulmonary Hypertension.
    Plecitá-Hlavatá L; Tauber J; Li M; Zhang H; Flockton AR; Pullamsetti SS; Chelladurai P; D'Alessandro A; El Kasmi KC; Ježek P; Stenmark KR
    Am J Respir Cell Mol Biol; 2016 Jul; 55(1):47-57. PubMed ID: 26699943
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblasts.
    Wang D; Zhang H; Li M; Frid MG; Flockton AR; McKeon BA; Yeager ME; Fini MA; Morrell NW; Pullamsetti SS; Velegala S; Seeger W; McKinsey TA; Sucharov CC; Stenmark KR
    Circ Res; 2014 Jan; 114(1):67-78. PubMed ID: 24122720
    [TBL] [Abstract][Full Text] [Related]  

  • 9. OPN silencing reduces hypoxic pulmonary hypertension via PI3K-AKT-induced protective autophagy.
    Zhou R; Li R; Ding Q; Zhang Y; Yang H; Han Y; Liu C; Liu J; Wang S
    Sci Rep; 2024 Apr; 14(1):8670. PubMed ID: 38622371
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Osteopontin is an important mediator of alcoholic liver disease via hepatic stellate cell activation.
    Seth D; Duly A; Kuo PC; McCaughan GW; Haber PS
    World J Gastroenterol; 2014 Sep; 20(36):13088-104. PubMed ID: 25278703
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hypoxia induces unique proliferative response in adventitial fibroblasts by activating PDGFβ receptor-JNK1 signalling.
    Panzhinskiy E; Zawada WM; Stenmark KR; Das M
    Cardiovasc Res; 2012 Aug; 95(3):356-65. PubMed ID: 22735370
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Osteopontin increases lung cancer cells migration via activation of the alphavbeta3 integrin/FAK/Akt and NF-kappaB-dependent pathway.
    Fong YC; Liu SC; Huang CY; Li TM; Hsu SF; Kao ST; Tsai FJ; Chen WC; Chen CY; Tang CH
    Lung Cancer; 2009 Jun; 64(3):263-70. PubMed ID: 18996613
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Effect of Hypoxia-inducible Factor Inhibition on the Phenotype of Fibroblasts in Human and Bovine Pulmonary Hypertension.
    Hu CJ; Laux A; Gandjeva A; Wang L; Li M; Brown RD; Riddle S; Kheyfets VO; Tuder RM; Zhang H; Stenmark KR
    Am J Respir Cell Mol Biol; 2023 Jul; 69(1):73-86. PubMed ID: 36944195
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hypoxia downregulates PPARγ via an ERK1/2-NF-κB-Nox4-dependent mechanism in human pulmonary artery smooth muscle cells.
    Lu X; Bijli KM; Ramirez A; Murphy TC; Kleinhenz J; Hart CM
    Free Radic Biol Med; 2013 Oct; 63():151-60. PubMed ID: 23684777
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolic reprogramming and inflammation act in concert to control vascular remodeling in hypoxic pulmonary hypertension.
    Stenmark KR; Tuder RM; El Kasmi KC
    J Appl Physiol (1985); 2015 Nov; 119(10):1164-72. PubMed ID: 25930027
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of phosphatidylinositol 3-kinase, Akt, and mammalian target of rapamycin is necessary for hypoxia-induced pulmonary artery adventitial fibroblast proliferation.
    Gerasimovskaya EV; Tucker DA; Stenmark KR
    J Appl Physiol (1985); 2005 Feb; 98(2):722-31. PubMed ID: 15501927
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Downregulation of type II bone morphogenetic protein receptor in hypoxic pulmonary hypertension.
    Takahashi H; Goto N; Kojima Y; Tsuda Y; Morio Y; Muramatsu M; Fukuchi Y
    Am J Physiol Lung Cell Mol Physiol; 2006 Mar; 290(3):L450-8. PubMed ID: 16361357
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Microenvironmental regulation of T-cells in pulmonary hypertension.
    Plecitá-Hlavatá L; Brázdová A; Křivonosková M; Hu CJ; Phang T; Tauber J; Li M; Zhang H; Hoetzenecker K; Crnkovic S; Kwapiszewska G; Stenmark KR
    Front Immunol; 2023; 14():1223122. PubMed ID: 37497214
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sustained hypoxia leads to the emergence of cells with enhanced growth, migratory, and promitogenic potentials within the distal pulmonary artery wall.
    Frid MG; Li M; Gnanasekharan M; Burke DL; Fragoso M; Strassheim D; Sylman JL; Stenmark KR
    Am J Physiol Lung Cell Mol Physiol; 2009 Dec; 297(6):L1059-72. PubMed ID: 19767409
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High proliferative potential endothelial colony-forming cells contribute to hypoxia-induced pulmonary artery vasa vasorum neovascularization.
    Nijmeh H; Balasubramaniam V; Burns N; Ahmad A; Stenmark KR; Gerasimovskaya EV
    Am J Physiol Lung Cell Mol Physiol; 2014 Apr; 306(7):L661-71. PubMed ID: 24508729
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.