BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 22586083)

  • 1. 2-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy.
    Terés S; Lladó V; Higuera M; Barceló-Coblijn G; Martin ML; Noguera-Salvà MA; Marcilla-Etxenike A; García-Verdugo JM; Soriano-Navarro M; Saus C; Gómez-Pinedo U; Busquets X; Escribá PV
    Proc Natl Acad Sci U S A; 2012 May; 109(22):8489-94. PubMed ID: 22586083
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential effect of 2-hydroxyoleic acid enantiomers on protein (sphingomyelin synthase) and lipid (membrane) targets.
    Piotto S; Concilio S; Bianchino E; Iannelli P; López DJ; Terés S; Ibarguren M; Barceló-Coblijn G; Martin ML; Guardiola-Serrano F; Alonso-Sande M; Funari SS; Busquets X; Escribá PV
    Biochim Biophys Acta; 2014 Jun; 1838(6):1628-37. PubMed ID: 24412218
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy.
    Barceló-Coblijn G; Martin ML; de Almeida RF; Noguera-Salvà MA; Marcilla-Etxenike A; Guardiola-Serrano F; Lüth A; Kleuser B; Halver JE; Escribá PV
    Proc Natl Acad Sci U S A; 2011 Dec; 108(49):19569-74. PubMed ID: 22106271
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of the cancer cell membrane lipid composition by NaCHOleate: effects on cell signaling and therapeutical relevance in glioma.
    Lladó V; López DJ; Ibarguren M; Alonso M; Soriano JB; Escribá PV; Busquets X
    Biochim Biophys Acta; 2014 Jun; 1838(6):1619-27. PubMed ID: 24525074
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The role of membrane fatty acid remodeling in the antitumor mechanism of action of 2-hydroxyoleic acid.
    Martin ML; Barceló-Coblijn G; de Almeida RF; Noguera-Salvà MA; Terés S; Higuera M; Liebisch G; Schmitz G; Busquets X; Escribá PV
    Biochim Biophys Acta; 2013 May; 1828(5):1405-13. PubMed ID: 23360770
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Normalization of sphingomyelin levels by 2-hydroxyoleic acid induces autophagic cell death of SF767 cancer cells.
    Terés S; Lladó V; Higuera M; Barceló-Coblijn G; Martin ML; Noguera-Salvà MA; Marcilla-Etxenike A; García-Verdugo JM; Soriano-Navarro M; Saus C; Gómez-Pinedo U; Busquets X; Escribá PV
    Autophagy; 2012 Oct; 8(10):1542-4. PubMed ID: 22892762
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2-Hydroxyoleic acid induces ER stress and autophagy in various human glioma cell lines.
    Marcilla-Etxenike A; Martín ML; Noguera-Salvà MA; García-Verdugo JM; Soriano-Navarro M; Dey I; Escribá PV; Busquets X
    PLoS One; 2012; 7(10):e48235. PubMed ID: 23133576
    [TBL] [Abstract][Full Text] [Related]  

  • 8. NVP-BEZ235, a novel dual PI3K-mTOR inhibitor displays anti-glioma activity and reduces chemoresistance to temozolomide in human glioma cells.
    Yu Z; Xie G; Zhou G; Cheng Y; Zhang G; Yao G; Chen Y; Li Y; Zhao G
    Cancer Lett; 2015 Oct; 367(1):58-68. PubMed ID: 26188279
    [TBL] [Abstract][Full Text] [Related]  

  • 9. FK228 augmented temozolomide sensitivity in human glioma cells by blocking PI3K/AKT/mTOR signal pathways.
    Wu Y; Dong L; Bao S; Wang M; Yun Y; Zhu R
    Biomed Pharmacother; 2016 Dec; 84():462-469. PubMed ID: 27685789
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MSC-AS1 knockdown inhibits cell growth and temozolomide resistance by regulating miR-373-3p/CPEB4 axis in glioma through PI3K/Akt pathway.
    Li C; Feng S; Chen L
    Mol Cell Biochem; 2021 Feb; 476(2):699-713. PubMed ID: 33106913
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Efficacy of Onalespib, a Long-Acting Second-Generation HSP90 Inhibitor, as a Single Agent and in Combination with Temozolomide against Malignant Gliomas.
    Canella A; Welker AM; Yoo JY; Xu J; Abas FS; Kesanakurti D; Nagarajan P; Beattie CE; Sulman EP; Liu J; Gumin J; Lang FF; Gurcan MN; Kaur B; Sampath D; Puduvalli VK
    Clin Cancer Res; 2017 Oct; 23(20):6215-6226. PubMed ID: 28679777
    [No Abstract]   [Full Text] [Related]  

  • 12. Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells.
    Kanzawa T; Germano IM; Komata T; Ito H; Kondo Y; Kondo S
    Cell Death Differ; 2004 Apr; 11(4):448-57. PubMed ID: 14713959
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells.
    Shin SY; Lee KS; Choi YK; Lim HJ; Lee HG; Lim Y; Lee YH
    Carcinogenesis; 2013 Sep; 34(9):2080-9. PubMed ID: 23689352
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rational incorporation of selenium into temozolomide elicits superior antitumor activity associated with both apoptotic and autophagic cell death.
    Cheng Y; Sk UH; Zhang Y; Ren X; Zhang L; Huber-Keener KJ; Sun YW; Liao J; Amin S; Sharma AK; Yang JM
    PLoS One; 2012; 7(4):e35104. PubMed ID: 22496897
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Resveratrol enhances the therapeutic effect of temozolomide against malignant glioma in vitro and in vivo by inhibiting autophagy.
    Lin CJ; Lee CC; Shih YL; Lin TY; Wang SH; Lin YF; Shih CM
    Free Radic Biol Med; 2012 Jan; 52(2):377-91. PubMed ID: 22094224
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MiR-3116 sensitizes glioma cells to temozolomide by targeting FGFR1 and regulating the FGFR1/PI3K/AKT pathway.
    Kong S; Cao Y; Li X; Li Z; Xin Y; Meng Y
    J Cell Mol Med; 2020 Apr; 24(8):4677-4686. PubMed ID: 32181582
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Upregulation of CASC2 sensitized glioma to temozolomide cytotoxicity through autophagy inhibition by sponging miR-193a-5p and regulating mTOR expression.
    Jiang C; Shen F; Du J; Fang X; Li X; Su J; Wang X; Huang X; Liu Z
    Biomed Pharmacother; 2018 Jan; 97():844-850. PubMed ID: 29136760
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FOXM1-mediated NUF2 expression confers temozolomide resistance to human glioma cells by regulating autophagy via the PI3K/AKT/mTOR signaling pathway.
    Guo L; Wu Z
    Neuropathology; 2022 Oct; 42(5):430-446. PubMed ID: 35701983
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ConBr lectin modulates MAPKs and Akt pathways and triggers autophagic glioma cell death by a mechanism dependent upon caspase-8 activation.
    Wolin IAV; Heinrich IA; Nascimento APM; Welter PG; Sosa LDV; De Paul AL; Zanotto-Filho A; Nedel CB; Lima LD; Osterne VJS; Pinto-Junior VR; Nascimento KS; Cavada BS; Leal RB
    Biochimie; 2021 Jan; 180():186-204. PubMed ID: 33171216
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.