214 related articles for article (PubMed ID: 22586275)
1. Deconstructing Ras signaling in the thymus.
Kortum RL; Sommers CL; Pinski JM; Alexander CP; Merrill RK; Li W; Love PE; Samelson LE
Mol Cell Biol; 2012 Jul; 32(14):2748-59. PubMed ID: 22586275
[TBL] [Abstract][Full Text] [Related]
2. Targeted Sos1 deletion reveals its critical role in early T-cell development.
Kortum RL; Sommers CL; Alexander CP; Pinski JM; Li W; Grinberg A; Lee J; Love PE; Samelson LE
Proc Natl Acad Sci U S A; 2011 Jul; 108(30):12407-12. PubMed ID: 21746917
[TBL] [Abstract][Full Text] [Related]
3. Sos1 regulates sustained TCR-mediated Erk activation.
Poltorak M; Meinert I; Stone JC; Schraven B; Simeoni L
Eur J Immunol; 2014 May; 44(5):1535-40. PubMed ID: 24497027
[TBL] [Abstract][Full Text] [Related]
4. Ras and extracellular signal-regulated kinase signaling in thymocytes and T cells.
Kortum RL; Rouquette-Jazdanian AK; Samelson LE
Trends Immunol; 2013 Jun; 34(6):259-68. PubMed ID: 23506953
[TBL] [Abstract][Full Text] [Related]
5. Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1.
Reynolds LF; de Bettignies C; Norton T; Beeser A; Chernoff J; Tybulewicz VL
J Biol Chem; 2004 Apr; 279(18):18239-46. PubMed ID: 14764585
[TBL] [Abstract][Full Text] [Related]
6. RasGRP1 transmits prodifferentiation TCR signaling that is crucial for CD4 T cell development.
Priatel JJ; Chen X; Dhanji S; Abraham N; Teh HS
J Immunol; 2006 Aug; 177(3):1470-80. PubMed ID: 16849453
[TBL] [Abstract][Full Text] [Related]
7. Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival.
Baltanás FC; Pérez-Andrés M; Ginel-Picardo A; Diaz D; Jimeno D; Liceras-Boillos P; Kortum RL; Samelson LE; Orfao A; Santos E
Mol Cell Biol; 2013 Nov; 33(22):4562-78. PubMed ID: 24043312
[TBL] [Abstract][Full Text] [Related]
8. Preferential development of CD4 and CD8 T regulatory cells in RasGRP1-deficient mice.
Chen X; Priatel JJ; Chow MT; Teh HS
J Immunol; 2008 May; 180(9):5973-82. PubMed ID: 18424717
[TBL] [Abstract][Full Text] [Related]
9. Transgenic expression of RasGRP1 induces the maturation of double-negative thymocytes and enhances the production of CD8 single-positive thymocytes.
Norment AM; Bogatzki LY; Klinger M; Ojala EW; Bevan MJ; Kay RJ
J Immunol; 2003 Feb; 170(3):1141-9. PubMed ID: 12538669
[TBL] [Abstract][Full Text] [Related]
10. RasGRP1, but not RasGRP3, is required for efficient thymic β-selection and ERK activation downstream of CXCR4.
Golec DP; Dower NA; Stone JC; Baldwin TA
PLoS One; 2013; 8(1):e53300. PubMed ID: 23308188
[TBL] [Abstract][Full Text] [Related]
11. Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes.
Roose JP; Mollenauer M; Ho M; Kurosaki T; Weiss A
Mol Cell Biol; 2007 Apr; 27(7):2732-45. PubMed ID: 17283063
[TBL] [Abstract][Full Text] [Related]
12. The ability of Sos1 to oligomerize the adaptor protein LAT is separable from its guanine nucleotide exchange activity in vivo.
Kortum RL; Balagopalan L; Alexander CP; Garcia J; Pinski JM; Merrill RK; Nguyen PH; Li W; Agarwal I; Akpan IO; Sommers CL; Samelson LE
Sci Signal; 2013 Nov; 6(301):ra99. PubMed ID: 24222714
[TBL] [Abstract][Full Text] [Related]
13. Activation of extracellular signal-regulated kinase but not of p38 mitogen-activated protein kinase pathways in lymphocytes requires allosteric activation of SOS.
Jun JE; Yang M; Chen H; Chakraborty AK; Roose JP
Mol Cell Biol; 2013 Jun; 33(12):2470-84. PubMed ID: 23589333
[TBL] [Abstract][Full Text] [Related]
14. Differential Role of the RasGEFs Sos1 and Sos2 in Mouse Skin Homeostasis and Carcinogenesis.
Liceras-Boillos P; Jimeno D; García-Navas R; Lorenzo-Martín LF; Menacho-Marquez M; Segrelles C; Gómez C; Calzada N; Fuentes-Mateos R; Paramio JM; Bustelo XR; Baltanás FC; Santos E
Mol Cell Biol; 2018 Aug; 38(16):. PubMed ID: 29844066
[TBL] [Abstract][Full Text] [Related]
15. RasGRP1 opposes proliferative EGFR-SOS1-Ras signals and restricts intestinal epithelial cell growth.
Depeille P; Henricks LM; van de Ven RA; Lemmens E; Wang CY; Matli M; Werb Z; Haigis KM; Donner D; Warren R; Roose JP
Nat Cell Biol; 2015 Jun; 17(6):804-15. PubMed ID: 26005835
[TBL] [Abstract][Full Text] [Related]
16. The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties.
Qian X; Esteban L; Vass WC; Upadhyaya C; Papageorge AG; Yienger K; Ward JM; Lowy DR; Santos E
EMBO J; 2000 Feb; 19(4):642-54. PubMed ID: 10675333
[TBL] [Abstract][Full Text] [Related]
17. RasGRP1 and RasGRP3 Are Required for Efficient Generation of Early Thymic Progenitors.
Golec DP; Henao Caviedes LM; Baldwin TA
J Immunol; 2016 Sep; 197(5):1743-53. PubMed ID: 27465532
[TBL] [Abstract][Full Text] [Related]
18. Deregulated expression of RasGRP1 initiates thymic lymphomagenesis independently of T-cell receptors.
Klinger MB; Guilbault B; Goulding RE; Kay RJ
Oncogene; 2005 Apr; 24(16):2695-704. PubMed ID: 15829980
[TBL] [Abstract][Full Text] [Related]
19. IL-7- and IL-15-mediated TCR sensitization enables T cell responses to self-antigens.
Deshpande P; Cavanagh MM; Le Saux S; Singh K; Weyand CM; Goronzy JJ
J Immunol; 2013 Feb; 190(4):1416-23. PubMed ID: 23325887
[TBL] [Abstract][Full Text] [Related]
20. RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation.
Priatel JJ; Teh SJ; Dower NA; Stone JC; Teh HS
Immunity; 2002 Nov; 17(5):617-27. PubMed ID: 12433368
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]