BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

352 related articles for article (PubMed ID: 22587726)

  • 1. Establishing a toolkit for precursor-directed polyketide biosynthesis: exploring substrate promiscuities of acid-CoA ligases.
    Go MK; Chow JY; Cheung VW; Lim YP; Yew WS
    Biochemistry; 2012 Jun; 51(22):4568-79. PubMed ID: 22587726
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units.
    Ray L; Valentic TR; Miyazawa T; Withall DM; Song L; Milligan JC; Osada H; Takahashi S; Tsai SC; Challis GL
    Nat Commun; 2016 Dec; 7():13609. PubMed ID: 28000660
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Promiscuity of a modular polyketide synthase towards natural and non-natural extender units.
    Koryakina I; McArthur JB; Draelos MM; Williams GJ
    Org Biomol Chem; 2013 Jul; 11(27):4449-58. PubMed ID: 23681002
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cloning and characterization of a type III polyketide synthase from Aspergillus niger.
    Li J; Luo Y; Lee JK; Zhao H
    Bioorg Med Chem Lett; 2011 Oct; 21(20):6085-9. PubMed ID: 21903388
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic pathway engineering for complex polyketide biosynthesis in Saccharomyces cerevisiae.
    Mutka SC; Bondi SM; Carney JR; Da Silva NA; Kealey JT
    FEMS Yeast Res; 2006 Jan; 6(1):40-7. PubMed ID: 16423069
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Promiscuous fatty acyl CoA ligases produce acyl-CoA and acyl-SNAC precursors for polyketide biosynthesis.
    Arora P; Vats A; Saxena P; Mohanty D; Gokhale RS
    J Am Chem Soc; 2005 Jul; 127(26):9388-9. PubMed ID: 15984864
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enzymatic extender unit generation for in vitro polyketide synthase reactions: structural and functional showcasing of Streptomyces coelicolor MatB.
    Hughes AJ; Keatinge-Clay A
    Chem Biol; 2011 Feb; 18(2):165-76. PubMed ID: 21338915
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant malonyl-CoA synthetases with altered specificity for polyketide synthase extender unit generation.
    Koryakina I; Williams GJ
    Chembiochem; 2011 Oct; 12(15):2289-93. PubMed ID: 23106079
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhancing the atom economy of polyketide biosynthetic processes through metabolic engineering.
    Lombó F; Pfeifer B; Leaf T; Ou S; Kim YS; Cane DE; Licari P; Khosla C
    Biotechnol Prog; 2001; 17(4):612-7. PubMed ID: 11485419
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Poly specific trans-acyltransferase machinery revealed via engineered acyl-CoA synthetases.
    Koryakina I; McArthur J; Randall S; Draelos MM; Musiol EM; Muddiman DC; Weber T; Williams GJ
    ACS Chem Biol; 2013 Jan; 8(1):200-8. PubMed ID: 23083014
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of Middle Chain Fatty Acyl-CoA Ligase Responsible for the Biosynthesis of 2-Alkylmalonyl-CoAs for Polyketide Extender Unit.
    Miyazawa T; Takahashi S; Kawata A; Panthee S; Hayashi T; Shimizu T; Nogawa T; Osada H
    J Biol Chem; 2015 Nov; 290(45):26994-27011. PubMed ID: 26378232
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel applications of plant polyketide synthases.
    Abe I
    Curr Opin Chem Biol; 2012 Apr; 16(1-2):179-85. PubMed ID: 22245533
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Supramolecular templating in kirromycin biosynthesis: the acyltransferase KirCII loads ethylmalonyl-CoA extender onto a specific ACP of the trans-AT PKS.
    Musiol EM; Härtner T; Kulik A; Moldenhauer J; Piel J; Wohlleben W; Weber T
    Chem Biol; 2011 Apr; 18(4):438-44. PubMed ID: 21513880
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Engineered biosynthesis of plant polyketides: structure-based and precursor-directed approach.
    Abe I
    Top Curr Chem; 2010; 297():45-66. PubMed ID: 21495256
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Polyketide Starter and Extender Units Serve as Regulatory Ligands to Coordinate the Biosynthesis of Antibiotics in Actinomycetes.
    Wu P; Chen K; Li B; Zhang Y; Wu H; Chen Y; Ren S; Khan S; Zhang L; Zhang B
    mBio; 2021 Oct; 12(5):e0229821. PubMed ID: 34579580
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chemoenzymatic Synthesis and Biological Evaluation for Bioactive Molecules Derived from Bacterial Benzoyl Coenzyme A Ligase and Plant Type III Polyketide Synthase.
    Adhikari K; Lo IW; Chen CL; Wang YL; Lin KH; Zadeh SM; Rattinam R; Li YS; Wu CJ; Li TL
    Biomolecules; 2020 May; 10(5):. PubMed ID: 32397467
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Beyond ethylmalonyl-CoA: the functional role of crotonyl-CoA carboxylase/reductase homologs in expanding polyketide diversity.
    Wilson MC; Moore BS
    Nat Prod Rep; 2012 Jan; 29(1):72-86. PubMed ID: 22124767
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Chemo-Enzymatic Road Map to the Synthesis of CoA Esters.
    Peter DM; Vögeli B; Cortina NS; Erb TJ
    Molecules; 2016 Apr; 21(4):517. PubMed ID: 27104508
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Uncovering the formation and selection of benzylmalonyl-CoA from the biosynthesis of splenocin and enterocin reveals a versatile way to introduce amino acids into polyketide carbon scaffolds.
    Chang C; Huang R; Yan Y; Ma H; Dai Z; Zhang B; Deng Z; Liu W; Qu X
    J Am Chem Soc; 2015 Apr; 137(12):4183-90. PubMed ID: 25763681
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.
    Dunn BJ; Watts KR; Robbins T; Cane DE; Khosla C
    Biochemistry; 2014 Jun; 53(23):3796-806. PubMed ID: 24871074
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.