262 related articles for article (PubMed ID: 22589271)
1. SIRT3 is a mitochondrial tumor suppressor: a scientific tale that connects aberrant cellular ROS, the Warburg effect, and carcinogenesis.
Haigis MC; Deng CX; Finley LW; Kim HS; Gius D
Cancer Res; 2012 May; 72(10):2468-72. PubMed ID: 22589271
[TBL] [Abstract][Full Text] [Related]
2. SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production.
Bell EL; Emerling BM; Ricoult SJ; Guarente L
Oncogene; 2011 Jun; 30(26):2986-96. PubMed ID: 21358671
[TBL] [Abstract][Full Text] [Related]
3. SIRT3 elicited an anti-Warburg effect through HIF1α/PDK1/PDHA1 to inhibit cholangiocarcinoma tumorigenesis.
Xu L; Li Y; Zhou L; Dorfman RG; Liu L; Cai R; Jiang C; Tang D; Wang Y; Zou X; Wang L; Zhang M
Cancer Med; 2019 May; 8(5):2380-2391. PubMed ID: 30993888
[TBL] [Abstract][Full Text] [Related]
4. SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization.
Finley LW; Carracedo A; Lee J; Souza A; Egia A; Zhang J; Teruya-Feldstein J; Moreira PI; Cardoso SM; Clish CB; Pandolfi PP; Haigis MC
Cancer Cell; 2011 Mar; 19(3):416-28. PubMed ID: 21397863
[TBL] [Abstract][Full Text] [Related]
5. SIRT3 controls cancer metabolic reprogramming by regulating ROS and HIF.
Schumacker PT
Cancer Cell; 2011 Mar; 19(3):299-300. PubMed ID: 21397853
[TBL] [Abstract][Full Text] [Related]
6. Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis.
Kong X; Wang R; Xue Y; Liu X; Zhang H; Chen Y; Fang F; Chang Y
PLoS One; 2010 Jul; 5(7):e11707. PubMed ID: 20661474
[TBL] [Abstract][Full Text] [Related]
7. Loss of SIRT3 Provides Growth Advantage for B Cell Malignancies.
Yu W; Denu RA; Krautkramer KA; Grindle KM; Yang DT; Asimakopoulos F; Hematti P; Denu JM
J Biol Chem; 2016 Feb; 291(7):3268-79. PubMed ID: 26631723
[TBL] [Abstract][Full Text] [Related]
8. SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress.
Kim HS; Patel K; Muldoon-Jacobs K; Bisht KS; Aykin-Burns N; Pennington JD; van der Meer R; Nguyen P; Savage J; Owens KM; Vassilopoulos A; Ozden O; Park SH; Singh KK; Abdulkadir SA; Spitz DR; Deng CX; Gius D
Cancer Cell; 2010 Jan; 17(1):41-52. PubMed ID: 20129246
[TBL] [Abstract][Full Text] [Related]
9. Vosaroxin induces mitochondrial dysfunction and apoptosis in cervical cancer HeLa cells: Involvement of AMPK/Sirt3/HIF-1 pathway.
Zhao XL; Yu CZ
Chem Biol Interact; 2018 Jun; 290():57-63. PubMed ID: 29800573
[TBL] [Abstract][Full Text] [Related]
10. SirT3 regulates the mitochondrial unfolded protein response.
Papa L; Germain D
Mol Cell Biol; 2014 Feb; 34(4):699-710. PubMed ID: 24324009
[TBL] [Abstract][Full Text] [Related]
11. SIRT3 Overexpression Inhibits Growth of Kidney Tumor Cells and Enhances Mitochondrial Biogenesis.
Liu H; Li S; Liu X; Chen Y; Deng H
J Proteome Res; 2018 Sep; 17(9):3143-3152. PubMed ID: 30095923
[TBL] [Abstract][Full Text] [Related]
12. The Warburg effect: essential part of metabolic reprogramming and central contributor to cancer progression.
Vaupel P; Schmidberger H; Mayer A
Int J Radiat Biol; 2019 Jul; 95(7):912-919. PubMed ID: 30822194
[TBL] [Abstract][Full Text] [Related]
13. A tumor suppressor SIRTainty.
Schumacker PT
Cancer Cell; 2010 Jan; 17(1):5-6. PubMed ID: 20129243
[TBL] [Abstract][Full Text] [Related]
14. Sirt3, mitochondrial ROS, ageing, and carcinogenesis.
Park SH; Ozden O; Jiang H; Cha YI; Pennington JD; Aykin-Burns N; Spitz DR; Gius D; Kim HS
Int J Mol Sci; 2011; 12(9):6226-39. PubMed ID: 22016654
[TBL] [Abstract][Full Text] [Related]
15. Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis.
Guzy RD; Sharma B; Bell E; Chandel NS; Schumacker PT
Mol Cell Biol; 2008 Jan; 28(2):718-31. PubMed ID: 17967865
[TBL] [Abstract][Full Text] [Related]
16. High-fat diet induces cardiac remodelling and dysfunction: assessment of the role played by SIRT3 loss.
Zeng H; Vaka VR; He X; Booz GW; Chen JX
J Cell Mol Med; 2015 Aug; 19(8):1847-56. PubMed ID: 25782072
[TBL] [Abstract][Full Text] [Related]
17. Transglutaminase 2 reprogramming of glucose metabolism in mammary epithelial cells via activation of inflammatory signaling pathways.
Kumar S; Donti TR; Agnihotri N; Mehta K
Int J Cancer; 2014 Jun; 134(12):2798-807. PubMed ID: 24477458
[TBL] [Abstract][Full Text] [Related]
18. Hypoxic preconditioning combined with curcumin promotes cell survival and mitochondrial quality of bone marrow mesenchymal stem cells, and accelerates cutaneous wound healing via PGC-1α/SIRT3/HIF-1α signaling.
Wang X; Shen K; Wang J; Liu K; Wu G; Li Y; Luo L; Zheng Z; Hu D
Free Radic Biol Med; 2020 Nov; 159():164-176. PubMed ID: 32745765
[TBL] [Abstract][Full Text] [Related]
19. Resveratrol suppresses cancer cell glucose uptake by targeting reactive oxygen species-mediated hypoxia-inducible factor-1α activation.
Jung KH; Lee JH; Thien Quach CH; Paik JY; Oh H; Park JW; Lee EJ; Moon SH; Lee KH
J Nucl Med; 2013 Dec; 54(12):2161-7. PubMed ID: 24221993
[TBL] [Abstract][Full Text] [Related]
20. The Apoptotic Effect of HIF-1α Inhibition Combined with Glucose plus Insulin Treatment on Gastric Cancer under Hypoxic Conditions.
Tanaka T; Kitajima Y; Miyake S; Yanagihara K; Hara H; Nishijima-Matsunobu A; Baba K; Shida M; Wakiyama K; Nakamura J; Noshiro H
PLoS One; 2015; 10(9):e0137257. PubMed ID: 26339797
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
