327 related articles for article (PubMed ID: 22589546)
1. Crystal structure of the acyltransferase domain of the iterative polyketide synthase in enediyne biosynthesis.
Liew CW; Nilsson M; Chen MW; Sun H; Cornvik T; Liang ZX; Lescar J
J Biol Chem; 2012 Jun; 287(27):23203-15. PubMed ID: 22589546
[TBL] [Abstract][Full Text] [Related]
2. A dual role for a polyketide synthase in dynemicin enediyne and anthraquinone biosynthesis.
Cohen DR; Townsend CA
Nat Chem; 2018 Feb; 10(2):231-236. PubMed ID: 29359752
[TBL] [Abstract][Full Text] [Related]
3. Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases.
Liou GF; Lau J; Cane DE; Khosla C
Biochemistry; 2003 Jan; 42(1):200-7. PubMed ID: 12515555
[TBL] [Abstract][Full Text] [Related]
4. Mechanism and specificity of an acyltransferase domain from a modular polyketide synthase.
Dunn BJ; Cane DE; Khosla C
Biochemistry; 2013 Mar; 52(11):1839-41. PubMed ID: 23452124
[TBL] [Abstract][Full Text] [Related]
5. Induced-fit upon ligand binding revealed by crystal structures of the hot-dog fold thioesterase in dynemicin biosynthesis.
Liew CW; Sharff A; Kotaka M; Kong R; Sun H; Qureshi I; Bricogne G; Liang ZX; Lescar J
J Mol Biol; 2010 Nov; 404(2):291-306. PubMed ID: 20888341
[TBL] [Abstract][Full Text] [Related]
6. Biochemical characterization of the minimal domains of an iterative eukaryotic polyketide synthase.
Sabatini M; Comba S; Altabe S; Recio-Balsells AI; Labadie GR; Takano E; Gramajo H; Arabolaza A
FEBS J; 2018 Dec; 285(23):4494-4511. PubMed ID: 30300504
[TBL] [Abstract][Full Text] [Related]
7. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.
Dunn BJ; Watts KR; Robbins T; Cane DE; Khosla C
Biochemistry; 2014 Jun; 53(23):3796-806. PubMed ID: 24871074
[TBL] [Abstract][Full Text] [Related]
8. A polyketide synthase acyltransferase domain structure suggests a recognition mechanism for its hydroxymalonyl-acyl carrier protein substrate.
Park H; Kevany BM; Dyer DH; Thomas MG; Forest KT
PLoS One; 2014; 9(10):e110965. PubMed ID: 25340352
[TBL] [Abstract][Full Text] [Related]
9. Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase.
Kalkreuter E; Bingham KS; Keeler AM; Lowell AN; Schmidt JJ; Sherman DH; Williams GJ
Nat Commun; 2021 Apr; 12(1):2193. PubMed ID: 33850151
[TBL] [Abstract][Full Text] [Related]
10. GNAT-like strategy for polyketide chain initiation.
Gu L; Geders TW; Wang B; Gerwick WH; Håkansson K; Smith JL; Sherman DH
Science; 2007 Nov; 318(5852):970-4. PubMed ID: 17991863
[TBL] [Abstract][Full Text] [Related]
11. Alteration of the substrate specificity of the malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase domain of the multifunctional fatty acid synthase by mutation of a single arginine residue.
Rangan VS; Smith S
J Biol Chem; 1997 May; 272(18):11975-8. PubMed ID: 9115261
[TBL] [Abstract][Full Text] [Related]
12. Activity of Fatty Acid Biosynthesis Initiating Ketosynthase FabH with Acetyl/Malonyl-oxa/aza(dethia)CoAs.
Boram TJ; Benjamin AB; Silva de Sousa A; Stunkard LM; Stewart TA; Adams TJ; Craft NA; Velázquez-Marrero KG; Ling J; Nice JN; Lohman JR
ACS Chem Biol; 2023 Jan; 18(1):49-58. PubMed ID: 36626717
[TBL] [Abstract][Full Text] [Related]
13. Structural Insights into the Substrate Specificity of Acyltransferases from Salinomycin Polyketide Synthase.
Zhang F; Shi T; Ji H; Ali I; Huang S; Deng Z; Min Q; Bai L; Zhao Y; Zheng J
Biochemistry; 2019 Jul; 58(27):2978-2986. PubMed ID: 31199122
[TBL] [Abstract][Full Text] [Related]
14. Biochemical characterization of a malonyl-specific acyltransferase domain of FK506 biosynthetic polyketide synthase.
Wang YY; Bai LF; Ran XX; Jiang XH; Wu H; Zhang W; Jin MY; Li YQ; Jiang H
Protein Pept Lett; 2015; 22(1):2-7. PubMed ID: 25267255
[TBL] [Abstract][Full Text] [Related]
15. The AT₂ domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS.
Musiol EM; Greule A; Härtner T; Kulik A; Wohlleben W; Weber T
Chembiochem; 2013 Jul; 14(11):1343-52. PubMed ID: 23828654
[TBL] [Abstract][Full Text] [Related]
16. Acyl hydrolases from trans-AT polyketide synthases target acetyl units on acyl carrier proteins.
Jenner M; Afonso JP; Kohlhaas C; Karbaum P; Frank S; Piel J; Oldham NJ
Chem Commun (Camb); 2016 Apr; 52(30):5262-5. PubMed ID: 27003309
[TBL] [Abstract][Full Text] [Related]
17. Supramolecular templating in kirromycin biosynthesis: the acyltransferase KirCII loads ethylmalonyl-CoA extender onto a specific ACP of the trans-AT PKS.
Musiol EM; Härtner T; Kulik A; Moldenhauer J; Piel J; Wohlleben W; Weber T
Chem Biol; 2011 Apr; 18(4):438-44. PubMed ID: 21513880
[TBL] [Abstract][Full Text] [Related]
18. Mechanistic analysis of a type II polyketide synthase. Role of conserved residues in the beta-ketoacyl synthase-chain length factor heterodimer.
Dreier J; Khosla C
Biochemistry; 2000 Feb; 39(8):2088-95. PubMed ID: 10684659
[TBL] [Abstract][Full Text] [Related]
19. Biochemical characterization of the minimal polyketide synthase domains in the lovastatin nonaketide synthase LovB.
Ma SM; Tang Y
FEBS J; 2007 Jun; 274(11):2854-64. PubMed ID: 17466016
[TBL] [Abstract][Full Text] [Related]
20. Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases.
Haydock SF; Aparicio JF; Molnár I; Schwecke T; Khaw LE; König A; Marsden AF; Galloway IS; Staunton J; Leadlay PF
FEBS Lett; 1995 Oct; 374(2):246-8. PubMed ID: 7589545
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
