These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 22590625)

  • 1. Perifosine as a potential novel anti-cancer agent inhibits EGFR/MET-AKT axis in malignant pleural mesothelioma.
    Pinton G; Manente AG; Angeli G; Mutti L; Moro L
    PLoS One; 2012; 7(5):e36856. PubMed ID: 22590625
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Perifosine, a novel alkylphospholipid, inhibits protein kinase B activation.
    Kondapaka SB; Singh SS; Dasmahapatra GP; Sausville EA; Roy KK
    Mol Cancer Ther; 2003 Nov; 2(11):1093-103. PubMed ID: 14617782
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel ATP-competitive Akt inhibitor afuresertib suppresses the proliferation of malignant pleural mesothelioma cells.
    Yamaji M; Ota A; Wahiduzzaman M; Karnan S; Hyodo T; Konishi H; Tsuzuki S; Hosokawa Y; Haniuda M
    Cancer Med; 2017 Nov; 6(11):2646-2659. PubMed ID: 28960945
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Perifosine inhibits growth of human experimental endometrial cancers by blockade of AKT phosphorylation.
    Engel JB; Honig A; Schönhals T; Weidler C; Häusler S; Krockenberger M; Grunewald TG; Dombrowski Y; Rieger L; Dietl J; Wischhusen J
    Eur J Obstet Gynecol Reprod Biol; 2008 Nov; 141(1):64-9. PubMed ID: 18687514
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Coactivation of receptor tyrosine kinases in malignant mesothelioma as a rationale for combination targeted therapy.
    Brevet M; Shimizu S; Bott MJ; Shukla N; Zhou Q; Olshen AB; Rusch V; Ladanyi M
    J Thorac Oncol; 2011 May; 6(5):864-74. PubMed ID: 21774103
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Perifosine, an AKT inhibitor, modulates ovarian cancer cell line sensitivity to cisplatin-induced growth arrest.
    Al Sawah E; Chen X; Marchion DC; Xiong Y; Ramirez IJ; Abbasi F; Bou Zgheib N; Chon HS; Wenham RM; Apte SM; Judson PL; Lancaster JM
    Gynecol Oncol; 2013 Oct; 131(1):207-12. PubMed ID: 23877012
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Preclinical evaluation of perifosine as a potential promising anti-rhabdomyosarcoma agent.
    Shen J; Hong Y; Zhao Q; Zhang JL
    Tumour Biol; 2016 Jan; 37(1):1025-33. PubMed ID: 26269112
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo.
    Momota H; Nerio E; Holland EC
    Cancer Res; 2005 Aug; 65(16):7429-35. PubMed ID: 16103096
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro and in vivo inhibition of neuroblastoma tumor cell growth by AKT inhibitor perifosine.
    Li Z; Tan F; Liewehr DJ; Steinberg SM; Thiele CJ
    J Natl Cancer Inst; 2010 Jun; 102(11):758-70. PubMed ID: 20463309
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Preclinical Efficacy for AKT Targeting in Clear Cell Carcinoma of the Ovary.
    Sasano T; Mabuchi S; Kuroda H; Kawano M; Matsumoto Y; Takahashi R; Hisamatsu T; Sawada K; Hashimoto K; Isobe A; Testa JR; Kimura T
    Mol Cancer Res; 2015 Apr; 13(4):795-806. PubMed ID: 25519148
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vitro combination treatment with perifosine and UCN-01 demonstrates synergism against prostate (PC-3) and lung (A549) epithelial adenocarcinoma cell lines.
    Dasmahapatra GP; Didolkar P; Alley MC; Ghosh S; Sausville EA; Roy KK
    Clin Cancer Res; 2004 Aug; 10(15):5242-52. PubMed ID: 15297428
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.
    Elrod HA; Lin YD; Yue P; Wang X; Lonial S; Khuri FR; Sun SY
    Mol Cancer Ther; 2007 Jul; 6(7):2029-38. PubMed ID: 17604333
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The alkylphospholipid perifosine induces apoptosis and p21-mediated cell cycle arrest in medulloblastoma.
    Kumar A; Fillmore HL; Kadian R; Broaddus WC; Tye GW; Van Meter TE
    Mol Cancer Res; 2009 Nov; 7(11):1813-21. PubMed ID: 19887560
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Estrogen receptor β exerts tumor repressive functions in human malignant pleural mesothelioma via EGFR inactivation and affects response to gefitinib.
    Pinton G; Thomas W; Bellini P; Manente AG; Favoni RE; Harvey BJ; Mutti L; Moro L
    PLoS One; 2010 Nov; 5(11):e14110. PubMed ID: 21124760
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Combination treatment of prostate cancer cell lines with bioactive soy isoflavones and perifosine causes increased growth arrest and/or apoptosis.
    Vinall RL; Hwa K; Ghosh P; Pan CX; Lara PN; de Vere White RW
    Clin Cancer Res; 2007 Oct; 13(20):6204-16. PubMed ID: 17947488
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy.
    Fu L; Kim YA; Wang X; Wu X; Yue P; Lonial S; Khuri FR; Sun SY
    Cancer Res; 2009 Dec; 69(23):8967-76. PubMed ID: 19920197
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Perifosine: update on a novel Akt inhibitor.
    Gills JJ; Dennis PA
    Curr Oncol Rep; 2009 Mar; 11(2):102-10. PubMed ID: 19216841
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhancement of antitumor activity of the anti-EGF receptor monoclonal antibody cetuximab/C225 by perifosine in PTEN-deficient cancer cells.
    Li X; Luwor R; Lu Y; Liang K; Fan Z
    Oncogene; 2006 Jan; 25(4):525-35. PubMed ID: 16170346
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Combined treatment with cisplatin and sirolimus to enhance cell death in human mesothelioma.
    Hartman ML; Esposito JM; Yeap BY; Sugarbaker DJ
    J Thorac Cardiovasc Surg; 2010 May; 139(5):1233-40. PubMed ID: 19853261
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells.
    Papa V; Tazzari PL; Chiarini F; Cappellini A; Ricci F; Billi AM; Evangelisti C; Ottaviani E; Martinelli G; Testoni N; McCubrey JA; Martelli AM
    Leukemia; 2008 Jan; 22(1):147-60. PubMed ID: 17928881
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.