141 related articles for article (PubMed ID: 22590625)
1. Perifosine as a potential novel anti-cancer agent inhibits EGFR/MET-AKT axis in malignant pleural mesothelioma.
Pinton G; Manente AG; Angeli G; Mutti L; Moro L
PLoS One; 2012; 7(5):e36856. PubMed ID: 22590625
[TBL] [Abstract][Full Text] [Related]
2. Perifosine, a novel alkylphospholipid, inhibits protein kinase B activation.
Kondapaka SB; Singh SS; Dasmahapatra GP; Sausville EA; Roy KK
Mol Cancer Ther; 2003 Nov; 2(11):1093-103. PubMed ID: 14617782
[TBL] [Abstract][Full Text] [Related]
3. Novel ATP-competitive Akt inhibitor afuresertib suppresses the proliferation of malignant pleural mesothelioma cells.
Yamaji M; Ota A; Wahiduzzaman M; Karnan S; Hyodo T; Konishi H; Tsuzuki S; Hosokawa Y; Haniuda M
Cancer Med; 2017 Nov; 6(11):2646-2659. PubMed ID: 28960945
[TBL] [Abstract][Full Text] [Related]
4. Perifosine inhibits growth of human experimental endometrial cancers by blockade of AKT phosphorylation.
Engel JB; Honig A; Schönhals T; Weidler C; Häusler S; Krockenberger M; Grunewald TG; Dombrowski Y; Rieger L; Dietl J; Wischhusen J
Eur J Obstet Gynecol Reprod Biol; 2008 Nov; 141(1):64-9. PubMed ID: 18687514
[TBL] [Abstract][Full Text] [Related]
5. Coactivation of receptor tyrosine kinases in malignant mesothelioma as a rationale for combination targeted therapy.
Brevet M; Shimizu S; Bott MJ; Shukla N; Zhou Q; Olshen AB; Rusch V; Ladanyi M
J Thorac Oncol; 2011 May; 6(5):864-74. PubMed ID: 21774103
[TBL] [Abstract][Full Text] [Related]
6. Perifosine, an AKT inhibitor, modulates ovarian cancer cell line sensitivity to cisplatin-induced growth arrest.
Al Sawah E; Chen X; Marchion DC; Xiong Y; Ramirez IJ; Abbasi F; Bou Zgheib N; Chon HS; Wenham RM; Apte SM; Judson PL; Lancaster JM
Gynecol Oncol; 2013 Oct; 131(1):207-12. PubMed ID: 23877012
[TBL] [Abstract][Full Text] [Related]
7. Preclinical evaluation of perifosine as a potential promising anti-rhabdomyosarcoma agent.
Shen J; Hong Y; Zhao Q; Zhang JL
Tumour Biol; 2016 Jan; 37(1):1025-33. PubMed ID: 26269112
[TBL] [Abstract][Full Text] [Related]
8. Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo.
Momota H; Nerio E; Holland EC
Cancer Res; 2005 Aug; 65(16):7429-35. PubMed ID: 16103096
[TBL] [Abstract][Full Text] [Related]
9. In vitro and in vivo inhibition of neuroblastoma tumor cell growth by AKT inhibitor perifosine.
Li Z; Tan F; Liewehr DJ; Steinberg SM; Thiele CJ
J Natl Cancer Inst; 2010 Jun; 102(11):758-70. PubMed ID: 20463309
[TBL] [Abstract][Full Text] [Related]
10. Preclinical Efficacy for AKT Targeting in Clear Cell Carcinoma of the Ovary.
Sasano T; Mabuchi S; Kuroda H; Kawano M; Matsumoto Y; Takahashi R; Hisamatsu T; Sawada K; Hashimoto K; Isobe A; Testa JR; Kimura T
Mol Cancer Res; 2015 Apr; 13(4):795-806. PubMed ID: 25519148
[TBL] [Abstract][Full Text] [Related]
11. In vitro combination treatment with perifosine and UCN-01 demonstrates synergism against prostate (PC-3) and lung (A549) epithelial adenocarcinoma cell lines.
Dasmahapatra GP; Didolkar P; Alley MC; Ghosh S; Sausville EA; Roy KK
Clin Cancer Res; 2004 Aug; 10(15):5242-52. PubMed ID: 15297428
[TBL] [Abstract][Full Text] [Related]
12. The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.
Elrod HA; Lin YD; Yue P; Wang X; Lonial S; Khuri FR; Sun SY
Mol Cancer Ther; 2007 Jul; 6(7):2029-38. PubMed ID: 17604333
[TBL] [Abstract][Full Text] [Related]
13. The alkylphospholipid perifosine induces apoptosis and p21-mediated cell cycle arrest in medulloblastoma.
Kumar A; Fillmore HL; Kadian R; Broaddus WC; Tye GW; Van Meter TE
Mol Cancer Res; 2009 Nov; 7(11):1813-21. PubMed ID: 19887560
[TBL] [Abstract][Full Text] [Related]
14. Estrogen receptor β exerts tumor repressive functions in human malignant pleural mesothelioma via EGFR inactivation and affects response to gefitinib.
Pinton G; Thomas W; Bellini P; Manente AG; Favoni RE; Harvey BJ; Mutti L; Moro L
PLoS One; 2010 Nov; 5(11):e14110. PubMed ID: 21124760
[TBL] [Abstract][Full Text] [Related]
15. Combination treatment of prostate cancer cell lines with bioactive soy isoflavones and perifosine causes increased growth arrest and/or apoptosis.
Vinall RL; Hwa K; Ghosh P; Pan CX; Lara PN; de Vere White RW
Clin Cancer Res; 2007 Oct; 13(20):6204-16. PubMed ID: 17947488
[TBL] [Abstract][Full Text] [Related]
16. Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy.
Fu L; Kim YA; Wang X; Wu X; Yue P; Lonial S; Khuri FR; Sun SY
Cancer Res; 2009 Dec; 69(23):8967-76. PubMed ID: 19920197
[TBL] [Abstract][Full Text] [Related]
17. Perifosine: update on a novel Akt inhibitor.
Gills JJ; Dennis PA
Curr Oncol Rep; 2009 Mar; 11(2):102-10. PubMed ID: 19216841
[TBL] [Abstract][Full Text] [Related]
18. Enhancement of antitumor activity of the anti-EGF receptor monoclonal antibody cetuximab/C225 by perifosine in PTEN-deficient cancer cells.
Li X; Luwor R; Lu Y; Liang K; Fan Z
Oncogene; 2006 Jan; 25(4):525-35. PubMed ID: 16170346
[TBL] [Abstract][Full Text] [Related]
19. Combined treatment with cisplatin and sirolimus to enhance cell death in human mesothelioma.
Hartman ML; Esposito JM; Yeap BY; Sugarbaker DJ
J Thorac Cardiovasc Surg; 2010 May; 139(5):1233-40. PubMed ID: 19853261
[TBL] [Abstract][Full Text] [Related]
20. Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells.
Papa V; Tazzari PL; Chiarini F; Cappellini A; Ricci F; Billi AM; Evangelisti C; Ottaviani E; Martinelli G; Testoni N; McCubrey JA; Martelli AM
Leukemia; 2008 Jan; 22(1):147-60. PubMed ID: 17928881
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]