173 related articles for article (PubMed ID: 22595614)
1. Role of mammary epithelial and stromal P450 enzymes in the clearance and metabolic activation of 7,12-dimethylbenz(a)anthracene in mice.
Lin Y; Yao Y; Liu S; Wang L; Moorthy B; Xiong D; Cheng T; Ding X; Gu J
Toxicol Lett; 2012 Jul; 212(2):97-105. PubMed ID: 22595614
[TBL] [Abstract][Full Text] [Related]
2. Characterization of CYP1B1 and CYP1A1 expression in human mammary epithelial cells: role of the aryl hydrocarbon receptor in polycyclic aromatic hydrocarbon metabolism.
Larsen MC; Angus WG; Brake PB; Eltom SE; Sukow KA; Jefcoate CR
Cancer Res; 1998 Jun; 58(11):2366-74. PubMed ID: 9622076
[TBL] [Abstract][Full Text] [Related]
3. Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation.
Kleiner HE; Vulimiri SV; Reed MJ; Uberecken A; DiGiovanni J
Chem Res Toxicol; 2002 Feb; 15(2):226-35. PubMed ID: 11849049
[TBL] [Abstract][Full Text] [Related]
4. CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice: correlation of CYP1B1-mediated DNA adducts with carcinogenicity.
Buters J; Quintanilla-Martinez L; Schober W; Soballa VJ; Hintermair J; Wolff T; Gonzalez FJ; Greim H
Carcinogenesis; 2003 Feb; 24(2):327-34. PubMed ID: 12584184
[TBL] [Abstract][Full Text] [Related]
5. Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas.
Buters JT; Sakai S; Richter T; Pineau T; Alexander DL; Savas U; Doehmer J; Ward JM; Jefcoate CR; Gonzalez FJ
Proc Natl Acad Sci U S A; 1999 Mar; 96(5):1977-82. PubMed ID: 10051580
[TBL] [Abstract][Full Text] [Related]
6. Role of cytochrome p4501 family members in the metabolic activation of polycyclic aromatic hydrocarbons in mouse epidermis.
Kleiner HE; Vulimiri SV; Hatten WB; Reed MJ; Nebert DW; Jefcoate CR; DiGiovanni J
Chem Res Toxicol; 2004 Dec; 17(12):1667-74. PubMed ID: 15606143
[TBL] [Abstract][Full Text] [Related]
7. Soy and whey proteins downregulate DMBA-induced liver and mammary gland CYP1 expression in female rats.
Rowlands JC; He L; Hakkak R; Ronis MJ; Badger TM
J Nutr; 2001 Dec; 131(12):3281-7. PubMed ID: 11739881
[TBL] [Abstract][Full Text] [Related]
8. Tissue distribution of DNA adducts in rats treated by intramammillary injection with dibenzo[a,l]pyrene, 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene.
Arif JM; Smith WA; Gupta RC
Mutat Res; 1997 Aug; 378(1-2):31-9. PubMed ID: 9288883
[TBL] [Abstract][Full Text] [Related]
9. CYP1A1 and CYP1B1 in blood-brain interfaces: CYP1A1-dependent bioactivation of 7,12-dimethylbenz(a)anthracene in endothelial cells.
Granberg L; Ostergren A; Brandt I; Brittebo EB
Drug Metab Dispos; 2003 Mar; 31(3):259-65. PubMed ID: 12584151
[TBL] [Abstract][Full Text] [Related]
10. Suppression of 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis by pre-initiation treatment of rats with beta-naphthoflavone coincides with decreased levels of the carcinogen-derived DNA adducts in the mammary gland.
Malejka-Giganti D; Bennett KK; Culp SJ; Beland FA; Shinozuka H; Bliss RL
Cancer Detect Prev; 2005; 29(4):338-47. PubMed ID: 16054776
[TBL] [Abstract][Full Text] [Related]
11. Patterns of DNA adduct formation in liver and mammary epithelial cells of rats treated with 7,12-dimethylbenz(a)anthracene, and selective effects of chemopreventive agents.
Izzotti A; Camoirano A; Cartiglia C; Grubbs CJ; Lubet RA; Kelloff GJ; De Flora S
Cancer Res; 1999 Sep; 59(17):4285-90. PubMed ID: 10485473
[TBL] [Abstract][Full Text] [Related]
12. Expression of the aryl hydrocarbon receptor/transcription factor (AhR) and AhR-regulated CYP1 gene transcripts in a rat model of mammary tumorigenesis.
Trombino AF; Near RI; Matulka RA; Yang S; Hafer LJ; Toselli PA; Kim DW; Rogers AE; Sonenshein GE; Sherr DH
Breast Cancer Res Treat; 2000 Sep; 63(2):117-31. PubMed ID: 11097088
[TBL] [Abstract][Full Text] [Related]
13. Naturally occurring coumarins inhibit 7,12-dimethylbenz[a]anthracene DNA adduct formation in mouse mammary gland.
Prince M; Campbell CT; Robertson TA; Wells AJ; Kleiner HE
Carcinogenesis; 2006 Jun; 27(6):1204-13. PubMed ID: 16387742
[TBL] [Abstract][Full Text] [Related]
14. Specificity of cDNA-expressed human and rodent cytochrome P450s in the oxidative metabolism of the potent carcinogen 7,12-dimethylbenz[a]anthracene.
Shou M; Korzekwa KR; Krausz KW; Buters JT; Grogan J; Goldfarb I; Hardwick JP; Gonzalez FJ; Gelboin HV
Mol Carcinog; 1996 Dec; 17(4):241-9. PubMed ID: 8989918
[TBL] [Abstract][Full Text] [Related]
15. Cytochromes CYP1A1 and CYP1B1 in the rat mammary gland: cell-specific expression and regulation by polycyclic aromatic hydrocarbons and hormones.
Christou M; Savas U; Schroeder S; Shen X; Thompson T; Gould MN; Jefcoate CR
Mol Cell Endocrinol; 1995 Nov; 115(1):41-50. PubMed ID: 8674863
[TBL] [Abstract][Full Text] [Related]
16. Bone marrow cytotoxicity of benzo[a]pyrene is dependent on CYP1B1 but is diminished by Ah receptor-mediated induction of CYP1A1 in liver.
Galván N; Jaskula-Sztul R; MacWilliams PS; Czuprynski CJ; Jefcoate CR
Toxicol Appl Pharmacol; 2003 Nov; 193(1):84-96. PubMed ID: 14613719
[TBL] [Abstract][Full Text] [Related]
17. Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7,12-dimethylbenz[a]anthracene.
Heidel SM; MacWilliams PS; Baird WM; Dashwood WM; Buters JT; Gonzalez FJ; Larsen MC; Czuprynski CJ; Jefcoate CR
Cancer Res; 2000 Jul; 60(13):3454-60. PubMed ID: 10910056
[TBL] [Abstract][Full Text] [Related]
18. The plasticizer benzyl butyl phthalate (BBP) inhibits 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary DNA adduct formation and tumorigenesis.
Singletary K; MacDonald C; Wallig M
Carcinogenesis; 1997 Aug; 18(8):1669-73. PubMed ID: 9276647
[TBL] [Abstract][Full Text] [Related]
19. Bone marrow stromal cell cytochrome P4501B1 is required for pre-B cell apoptosis induced by 7,12-dimethylbenz[a]anthracene.
Heidel SM; Holston K; Buters JT; Gonzalez FJ; Jefcoate CR; Czupyrynski CJ
Mol Pharmacol; 1999 Dec; 56(6):1317-23. PubMed ID: 10570060
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of carcinogen-activating enzymes by 16alpha-fluoro-5-androsten-17-one.
Ciolino HP; MacDonald CJ; Yeh GC
Cancer Res; 2002 Jul; 62(13):3685-90. PubMed ID: 12097275
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
