227 related articles for article (PubMed ID: 22596234)
21. Evodiamine suppresses Notch3 signaling in lung tumorigenesis via direct binding to γ-secretases.
Yang X; Zhang Y; Huang Y; Wang Y; Qi X; Su T; Lu L
Phytomedicine; 2020 Mar; 68():153176. PubMed ID: 32045841
[TBL] [Abstract][Full Text] [Related]
22. GSI-I (Z-LLNle-CHO) inhibits γ-secretase and the proteosome to trigger cell death in precursor-B acute lymphoblastic leukemia.
Meng X; Matlawska-Wasowska K; Girodon F; Mazel T; Willman CL; Atlas S; Chen IM; Harvey RC; Hunger SP; Ness SA; Winter SS; Wilson BS
Leukemia; 2011 Jul; 25(7):1135-46. PubMed ID: 21494254
[TBL] [Abstract][Full Text] [Related]
23. Preclinical profile of a potent gamma-secretase inhibitor targeting notch signaling with in vivo efficacy and pharmacodynamic properties.
Luistro L; He W; Smith M; Packman K; Vilenchik M; Carvajal D; Roberts J; Cai J; Berkofsky-Fessler W; Hilton H; Linn M; Flohr A; Jakob-Røtne R; Jacobsen H; Glenn K; Heimbrook D; Boylan JF
Cancer Res; 2009 Oct; 69(19):7672-80. PubMed ID: 19773430
[TBL] [Abstract][Full Text] [Related]
24. Rethinking Gamma-secretase Inhibitors for Treatment of Non-small-Cell Lung Cancer: Is Notch the Target?
Pine SR
Clin Cancer Res; 2018 Dec; 24(24):6136-6141. PubMed ID: 30104200
[TBL] [Abstract][Full Text] [Related]
25. Gamma secretase inhibitor enhances sensitivity to doxorubicin in MDA-MB-231 cells.
Li ZL; Chen C; Yang Y; Wang C; Yang T; Yang X; Liu SC
Int J Clin Exp Pathol; 2015; 8(5):4378-87. PubMed ID: 26191129
[TBL] [Abstract][Full Text] [Related]
26. Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation.
Vo K; Amarasinghe B; Washington K; Gonzalez A; Berlin J; Dang TP
Mol Cancer; 2011 Nov; 10():138. PubMed ID: 22074495
[TBL] [Abstract][Full Text] [Related]
27. Combined Bcl-2/mammalian target of rapamycin inhibition leads to enhanced radiosensitization via induction of apoptosis and autophagy in non-small cell lung tumor xenograft model.
Kim KW; Moretti L; Mitchell LR; Jung DK; Lu B
Clin Cancer Res; 2009 Oct; 15(19):6096-105. PubMed ID: 19773376
[TBL] [Abstract][Full Text] [Related]
28. Antiproliferative effects of γ-secretase inhibitor, a Notch signalling inhibitor, in multiple myeloma cells and its molecular mechanism of action.
Hu J; Zhu X; Lu Q
J Int Med Res; 2013 Aug; 41(4):1017-26. PubMed ID: 23839278
[TBL] [Abstract][Full Text] [Related]
29. Cervical Cancer Cell Growth, Drug Resistance, and Epithelial-Mesenchymal Transition Are Suppressed by y-Secretase Inhibitor RO4929097.
Wang L; Dai G; Yang J; Wu W; Zhang W
Med Sci Monit; 2018 Jun; 24():4046-4053. PubMed ID: 29899322
[TBL] [Abstract][Full Text] [Related]
30. GSI promotes vincristine-induced apoptosis by enhancing multi-polar spindle formation.
Singh A; Zapata MC; Choi YS; Yoon SO
Cell Cycle; 2014; 13(1):157-66. PubMed ID: 24200971
[TBL] [Abstract][Full Text] [Related]
31. Inhibition of gamma-secretase affects proliferation of leukemia and hepatoma cell lines through Notch signaling.
Suwanjunee S; Wongchana W; Palaga T
Anticancer Drugs; 2008 Jun; 19(5):477-86. PubMed ID: 18418214
[TBL] [Abstract][Full Text] [Related]
32. Inhibition of gamma-secretase activity impedes uterine serous carcinoma growth in a human xenograft model.
Groeneweg JW; Hall TR; Zhang L; Kim M; Byron VF; Tambouret R; Sathayanrayanan S; Foster R; Rueda BR; Growdon WB
Gynecol Oncol; 2014 Jun; 133(3):607-15. PubMed ID: 24667249
[TBL] [Abstract][Full Text] [Related]
33. Notch signalling in primary cutaneous CD30+ lymphoproliferative disorders: a new therapeutic approach?
Kamstrup MR; Biskup E; Gniadecki R
Br J Dermatol; 2010 Oct; 163(4):781-8. PubMed ID: 20560956
[TBL] [Abstract][Full Text] [Related]
34. Notch1 downregulation combined with interleukin-24 inhibits invasion and migration of hepatocellular carcinoma cells.
Han B; Liu SH; Guo WD; Zhang B; Wang JP; Cao YK; Liu J
World J Gastroenterol; 2015 Sep; 21(33):9727-35. PubMed ID: 26361419
[TBL] [Abstract][Full Text] [Related]
35. Down-regulation of Notch signaling by a γ-secretase inhibitor enhances the radiosensitivity of nasopharyngeal carcinoma cells.
Yu S; Zhang R; Liu F; Hu H; Yu S; Wang H
Oncol Rep; 2011 Nov; 26(5):1323-8. PubMed ID: 21805038
[TBL] [Abstract][Full Text] [Related]
36. Gamma-secretase inhibitor reduces allergic pulmonary inflammation by modulating Th1 and Th2 responses.
Kang JH; Kim BS; Uhm TG; Lee SH; Lee GR; Park CS; Chung IY
Am J Respir Crit Care Med; 2009 May; 179(10):875-82. PubMed ID: 19234107
[TBL] [Abstract][Full Text] [Related]
37. NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications.
Clementz AG; Rogowski A; Pandya K; Miele L; Osipo C
Breast Cancer Res; 2011 Jun; 13(3):R63. PubMed ID: 21679465
[TBL] [Abstract][Full Text] [Related]
38. Gambogic Acid Induces Apoptosis of Non-Small Cell Lung Cancer (NSCLC) Cells by Suppressing Notch Signaling.
Zhu M; Wang M; Jiang Y; Wu H; Lu G; Shi W; Cong D; Song S; Liu K; Wang H
Med Sci Monit; 2018 Oct; 24():7146-7151. PubMed ID: 30293083
[TBL] [Abstract][Full Text] [Related]
39. Notch signaling maintains proliferation and survival of the HL60 human promyelocytic leukemia cell line and promotes the phosphorylation of the Rb protein.
Li GH; Fan YZ; Liu XW; Zhang BF; Yin DD; He F; Huang SY; Kang ZJ; Xu H; Liu Q; Wu YL; Niu XL; Zhang L; Liu L; Hao MW; Han H; Liang YM
Mol Cell Biochem; 2010 Jul; 340(1-2):7-14. PubMed ID: 20157766
[TBL] [Abstract][Full Text] [Related]
40. MAML1 regulates cell viability via the NF-κB pathway in cervical cancer cell lines.
Kuncharin Y; Sangphech N; Kueanjinda P; Bhattarakosol P; Palaga T
Exp Cell Res; 2011 Aug; 317(13):1830-40. PubMed ID: 21640102
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]