632 related articles for article (PubMed ID: 22596249)
1. Akt promotes post-irradiation survival of human tumor cells through initiation, progression, and termination of DNA-PKcs-dependent DNA double-strand break repair.
Toulany M; Lee KJ; Fattah KR; Lin YF; Fehrenbacher B; Schaller M; Chen BP; Chen DJ; Rodemann HP
Mol Cancer Res; 2012 Jul; 10(7):945-57. PubMed ID: 22596249
[TBL] [Abstract][Full Text] [Related]
2. 2-Methoxyestradiol-induced radiosensitization is independent of SOD but depends on inhibition of Akt and DNA-PKcs activities.
Florczak U; Toulany M; Kehlbach R; Peter Rodemann H
Radiother Oncol; 2009 Sep; 92(3):334-8. PubMed ID: 19589609
[TBL] [Abstract][Full Text] [Related]
3. Suppression of DNA-dependent protein kinase sensitize cells to radiation without affecting DSB repair.
Gustafsson AS; Abramenkovs A; Stenerlöw B
Mutat Res; 2014 Nov; 769():1-10. PubMed ID: 25771720
[TBL] [Abstract][Full Text] [Related]
4. PI3K-Akt signaling regulates basal, but MAP-kinase signaling regulates radiation-induced XRCC1 expression in human tumor cells in vitro.
Toulany M; Dittmann K; Fehrenbacher B; Schaller M; Baumann M; Rodemann HP
DNA Repair (Amst); 2008 Oct; 7(10):1746-56. PubMed ID: 18678286
[TBL] [Abstract][Full Text] [Related]
5. Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair.
Toulany M; Kehlbach R; Florczak U; Sak A; Wang S; Chen J; Lobrich M; Rodemann HP
Mol Cancer Ther; 2008 Jul; 7(7):1772-81. PubMed ID: 18644989
[TBL] [Abstract][Full Text] [Related]
6. Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks.
Dong J; Zhang T; Ren Y; Wang Z; Ling CC; He F; Li GC; Wang C; Wen B
Oncotarget; 2017 Apr; 8(14):22662-22673. PubMed ID: 28186989
[TBL] [Abstract][Full Text] [Related]
7. DNA repair kinetics in SCID mice Sertoli cells and DNA-PKcs-deficient mouse embryonic fibroblasts.
Ahmed EA; Vélaz E; Rosemann M; Gilbertz KP; Scherthan H
Chromosoma; 2017 Mar; 126(2):287-298. PubMed ID: 27136939
[TBL] [Abstract][Full Text] [Related]
8. DNA-PK inhibition causes a low level of H2AX phosphorylation and homologous recombination repair in Medaka (Oryzias latipes) cells.
Urushihara Y; Kobayashi J; Matsumoto Y; Komatsu K; Oda S; Mitani H
Biochem Biophys Res Commun; 2012 Dec; 429(3-4):131-6. PubMed ID: 23142596
[TBL] [Abstract][Full Text] [Related]
9. DNA-PKcs deficiency inhibits glioblastoma cell-derived angiogenesis after ionizing radiation.
Liu Y; Zhang L; Liu Y; Sun C; Zhang H; Miao G; Di CX; Zhou X; Zhou R; Wang Z
J Cell Physiol; 2015 May; 230(5):1094-103. PubMed ID: 25294801
[TBL] [Abstract][Full Text] [Related]
10. Non-homologous end joining is the responsible pathway for the repair of fludarabine-induced DNA double strand breaks in mammalian cells.
de Campos-Nebel M; Larripa I; González-Cid M
Mutat Res; 2008 Nov; 646(1-2):8-16. PubMed ID: 18812179
[TBL] [Abstract][Full Text] [Related]
11. Regulation of ATM in DNA double strand break repair accounts for the radiosensitivity in human cells exposed to high linear energy transfer ionizing radiation.
Xue L; Yu D; Furusawa Y; Okayasu R; Tong J; Cao J; Fan S
Mutat Res; 2009 Nov; 670(1-2):15-23. PubMed ID: 19583974
[TBL] [Abstract][Full Text] [Related]
12. An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex.
Hammel M; Yu Y; Radhakrishnan SK; Chokshi C; Tsai MS; Matsumoto Y; Kuzdovich M; Remesh SG; Fang S; Tomkinson AE; Lees-Miller SP; Tainer JA
J Biol Chem; 2016 Dec; 291(53):26987-27006. PubMed ID: 27875301
[TBL] [Abstract][Full Text] [Related]
13. Genetic interaction between DNA repair factors PAXX, XLF, XRCC4 and DNA-PKcs in human cells.
Xing M; Oksenych V
FEBS Open Bio; 2019 Jul; 9(7):1315-1326. PubMed ID: 31141305
[TBL] [Abstract][Full Text] [Related]
14. Akt1 Stimulates Homologous Recombination Repair of DNA Double-Strand Breaks in a Rad51-Dependent Manner.
Mueck K; Rebholz S; Harati MD; Rodemann HP; Toulany M
Int J Mol Sci; 2017 Nov; 18(11):. PubMed ID: 29156644
[TBL] [Abstract][Full Text] [Related]
15. Analysis of DNA-dependent protein kinase-mediated DNA end joining by two-photon fluorescence cross-correlation spectroscopy.
Merkle D; Block WD; Yu Y; Lees-Miller SP; Cramb DT
Biochemistry; 2006 Apr; 45(13):4164-72. PubMed ID: 16566590
[TBL] [Abstract][Full Text] [Related]
16. Interactive competition between homologous recombination and non-homologous end joining.
Allen C; Halbrook J; Nickoloff JA
Mol Cancer Res; 2003 Oct; 1(12):913-20. PubMed ID: 14573792
[TBL] [Abstract][Full Text] [Related]
17. Repair-independent functions of DNA-PKcs protect irradiated cells from mitotic slippage and accelerated senescence.
Liu Y; Efimova EV; Ramamurthy A; Kron SJ
J Cell Sci; 2019 Jul; 132(13):. PubMed ID: 31189537
[TBL] [Abstract][Full Text] [Related]
18. Activating Akt1 mutations alter DNA double strand break repair and radiosensitivity.
Oeck S; Al-Refae K; Riffkin H; Wiel G; Handrick R; Klein D; Iliakis G; Jendrossek V
Sci Rep; 2017 Feb; 7():42700. PubMed ID: 28209968
[TBL] [Abstract][Full Text] [Related]
19. Survivin inhibition and DNA double-strand break repair: a molecular mechanism to overcome radioresistance in glioblastoma.
Reichert S; Rödel C; Mirsch J; Harter PN; Tomicic MT; Mittelbronn M; Kaina B; Rödel F
Radiother Oncol; 2011 Oct; 101(1):51-8. PubMed ID: 21852011
[TBL] [Abstract][Full Text] [Related]
20. K-RAS(V12) induces autocrine production of EGFR ligands and mediates radioresistance through EGFR-dependent Akt signaling and activation of DNA-PKcs.
Minjgee M; Toulany M; Kehlbach R; Giehl K; Rodemann HP
Int J Radiat Oncol Biol Phys; 2011 Dec; 81(5):1506-14. PubMed ID: 21985943
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]