214 related articles for article (PubMed ID: 22605333)
1. The tumor suppressor DiRas3 forms a complex with H-Ras and C-RAF proteins and regulates localization, dimerization, and kinase activity of C-RAF.
Baljuls A; Beck M; Oenel A; Robubi A; Kroschewski R; Hekman M; Rudel T; Rapp UR
J Biol Chem; 2012 Jun; 287(27):23128-40. PubMed ID: 22605333
[TBL] [Abstract][Full Text] [Related]
2. The tumour suppressor DiRas3 interacts with C-RAF and downregulates MEK activity to restrict cell migration.
Klingauf M; Beck M; Berge U; Turgay Y; Heinzer S; Horvath P; Kroschewski R
Biol Cell; 2013 Feb; 105(2):91-107. PubMed ID: 23157514
[TBL] [Abstract][Full Text] [Related]
3. Stabilization of C-RAF:KSR1 complex by DiRas3 reduces availability of C-RAF for dimerization with B-RAF.
Baljuls A; Dobrzyński M; Rauch J; Rauch N; Kolch W
Cell Signal; 2016 Oct; 28(10):1451-62. PubMed ID: 27368419
[TBL] [Abstract][Full Text] [Related]
4. DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters.
Sutton MN; Lu Z; Li YC; Zhou Y; Huang T; Reger AS; Hurwitz AM; Palzkill T; Logsdon C; Liang X; Gray JW; Nan X; Hancock J; Wahl GM; Bast RC
Cell Rep; 2019 Dec; 29(11):3448-3459.e6. PubMed ID: 31825828
[TBL] [Abstract][Full Text] [Related]
5. Calmodulin modulates H-Ras mediated Raf-1 activation.
Moretó J; Lladó A; Vidal-Quadras M; Calvo M; Pol A; Enrich C; Tebar F
Cell Signal; 2008 Jun; 20(6):1092-103. PubMed ID: 18356021
[TBL] [Abstract][Full Text] [Related]
6. Diacylglycerol kinase eta augments C-Raf activity and B-Raf/C-Raf heterodimerization.
Yasuda S; Kai M; Imai S; Takeishi K; Taketomi A; Toyota M; Kanoh H; Sakane F
J Biol Chem; 2009 Oct; 284(43):29559-70. PubMed ID: 19710016
[TBL] [Abstract][Full Text] [Related]
7. MEK-1 activates C-Raf through a Ras-independent mechanism.
Leicht DT; Balan V; Zhu J; Kaplun A; Bronisz A; Rana A; Tzivion G
Biochim Biophys Acta; 2013 May; 1833(5):976-86. PubMed ID: 23360980
[TBL] [Abstract][Full Text] [Related]
8. Cell type-specific importance of ras-c-raf complex association rate constants for MAPK signaling.
Kiel C; Serrano L
Sci Signal; 2009 Jul; 2(81):ra38. PubMed ID: 19638615
[TBL] [Abstract][Full Text] [Related]
9. Functional interactions of Raf and MEK with Jun-N-terminal kinase (JNK) result in a positive feedback loop on the oncogenic Ras signaling pathway.
Adler V; Qu Y; Smith SJ; Izotova L; Pestka S; Kung HF; Lin M; Friedman FK; Chie L; Chung D; Boutjdir M; Pincus MR
Biochemistry; 2005 Aug; 44(32):10784-95. PubMed ID: 16086581
[TBL] [Abstract][Full Text] [Related]
10. Wild-type and mutant B-RAF activate C-RAF through distinct mechanisms involving heterodimerization.
Garnett MJ; Rana S; Paterson H; Barford D; Marais R
Mol Cell; 2005 Dec; 20(6):963-9. PubMed ID: 16364920
[TBL] [Abstract][Full Text] [Related]
11. N terminus of ASPP2 binds to Ras and enhances Ras/Raf/MEK/ERK activation to promote oncogene-induced senescence.
Wang Z; Liu Y; Takahashi M; Van Hook K; Kampa-Schittenhelm KM; Sheppard BC; Sears RC; Stork PJ; Lopez CD
Proc Natl Acad Sci U S A; 2013 Jan; 110(1):312-7. PubMed ID: 23248303
[TBL] [Abstract][Full Text] [Related]
12. RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.
Hatzivassiliou G; Song K; Yen I; Brandhuber BJ; Anderson DJ; Alvarado R; Ludlam MJ; Stokoe D; Gloor SL; Vigers G; Morales T; Aliagas I; Liu B; Sideris S; Hoeflich KP; Jaiswal BS; Seshagiri S; Koeppen H; Belvin M; Friedman LS; Malek S
Nature; 2010 Mar; 464(7287):431-5. PubMed ID: 20130576
[TBL] [Abstract][Full Text] [Related]
13. Non-steroidal anti-inflammatory drugs suppress the ERK signaling pathway via block of Ras/c-Raf interaction and activation of MAP kinase phosphatases.
Pan MR; Chang HC; Hung WC
Cell Signal; 2008 Jun; 20(6):1134-41. PubMed ID: 18374541
[TBL] [Abstract][Full Text] [Related]
14. A structural model of a Ras-Raf signalosome.
Mysore VP; Zhou ZW; Ambrogio C; Li L; Kapp JN; Lu C; Wang Q; Tucker MR; Okoro JJ; Nagy-Davidescu G; Bai X; Plückthun A; Jänne PA; Westover KD; Shan Y; Shaw DE
Nat Struct Mol Biol; 2021 Oct; 28(10):847-857. PubMed ID: 34625747
[TBL] [Abstract][Full Text] [Related]
15. DIRAS3: An Imprinted Tumor Suppressor Gene that Regulates RAS and PI3K-driven Cancer Growth, Motility, Autophagy, and Tumor Dormancy.
Bildik G; Liang X; Sutton MN; Bast RC; Lu Z
Mol Cancer Ther; 2022 Jan; 21(1):25-37. PubMed ID: 34667114
[TBL] [Abstract][Full Text] [Related]
16. Protein kinase C alpha trigger Ras and Raf-independent MEK/ERK activation for TPA-induced growth inhibition of human hepatoma cell HepG2.
Wen-Sheng W
Cancer Lett; 2006 Jul; 239(1):27-35. PubMed ID: 16169661
[TBL] [Abstract][Full Text] [Related]
17. SPRED1 Interferes with K-ras but Not H-ras Membrane Anchorage and Signaling.
Siljamäki E; Abankwa D
Mol Cell Biol; 2016 Oct; 36(20):2612-25. PubMed ID: 27503857
[TBL] [Abstract][Full Text] [Related]
18. Regulation and role of Raf-1/B-Raf heterodimerization.
Rushworth LK; Hindley AD; O'Neill E; Kolch W
Mol Cell Biol; 2006 Mar; 26(6):2262-72. PubMed ID: 16508002
[TBL] [Abstract][Full Text] [Related]
19. Thrombin-stimulated cell proliferation mediated through activation of Ras/Raf/MEK/MAPK pathway in canine cultured tracheal smooth muscle cells.
Lin CC; Shyr MH; Chien CS; Wang CC; Chiu CT; Hsiao LD; Yang CM
Cell Signal; 2002 Mar; 14(3):265-75. PubMed ID: 11812655
[TBL] [Abstract][Full Text] [Related]
20. RAF1/BRAF dimerization integrates the signal from RAS to ERK and ROKα.
Varga A; Ehrenreiter K; Aschenbrenner B; Kocieniewski P; Kochanczyk M; Lipniacki T; Baccarini M
Sci Signal; 2017 Mar; 10(469):. PubMed ID: 28270557
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]