BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

497 related articles for article (PubMed ID: 22607974)

  • 1. The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity.
    Damgaard RB; Nachbur U; Yabal M; Wong WW; Fiil BK; Kastirr M; Rieser E; Rickard JA; Bankovacki A; Peschel C; Ruland J; Bekker-Jensen S; Mailand N; Kaufmann T; Strasser A; Walczak H; Silke J; Jost PJ; Gyrd-Hansen M
    Mol Cell; 2012 Jun; 46(6):746-58. PubMed ID: 22607974
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling.
    Damgaard RB; Fiil BK; Speckmann C; Yabal M; zur Stadt U; Bekker-Jensen S; Jost PJ; Ehl S; Mailand N; Gyrd-Hansen M
    EMBO Mol Med; 2013 Aug; 5(8):1278-95. PubMed ID: 23818254
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling.
    Goncharov T; Hedayati S; Mulvihill MM; Izrael-Tomasevic A; Zobel K; Jeet S; Fedorova AV; Eidenschenk C; deVoss J; Yu K; Shaw AS; Kirkpatrick DS; Fairbrother WJ; Deshayes K; Vucic D
    Mol Cell; 2018 Feb; 69(4):551-565.e7. PubMed ID: 29452636
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling.
    Hrdinka M; Schlicher L; Dai B; Pinkas DM; Bufton JC; Picaud S; Ward JA; Rogers C; Suebsuwong C; Nikhar S; Cuny GD; Huber KV; Filippakopoulos P; Bullock AN; Degterev A; Gyrd-Hansen M
    EMBO J; 2018 Sep; 37(17):. PubMed ID: 30026309
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease.
    Chirieleison SM; Marsh RA; Kumar P; Rathkey JK; Dubyak GR; Abbott DW
    J Biol Chem; 2017 Jun; 292(23):9666-9679. PubMed ID: 28404814
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann-Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease.
    Schwerd T; Pandey S; Yang HT; Bagola K; Jameson E; Jung J; Lachmann RH; Shah N; Patel SY; Booth C; Runz H; Düker G; Bettels R; Rohrbach M; Kugathasan S; Chapel H; Keshav S; Elkadri A; Platt N; Muise AM; Koletzko S; Xavier RJ; Marquardt T; Powrie F; Wraith JE; Gyrd-Hansen M; Platt FM; Uhlig HH
    Gut; 2017 Jun; 66(6):1060-1073. PubMed ID: 26953272
    [TBL] [Abstract][Full Text] [Related]  

  • 7. XIAP mediates NOD signaling via interaction with RIP2.
    Krieg A; Correa RG; Garrison JB; Le Negrate G; Welsh K; Huang Z; Knoefel WT; Reed JC
    Proc Natl Acad Sci U S A; 2009 Aug; 106(34):14524-9. PubMed ID: 19667203
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A regulatory region on RIPK2 is required for XIAP binding and NOD signaling activity.
    Heim VJ; Dagley LF; Stafford CA; Hansen FM; Clayer E; Bankovacki A; Webb AI; Lucet IS; Silke J; Nachbur U
    EMBO Rep; 2020 Nov; 21(11):e50400. PubMed ID: 32954645
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of Crohn disease in X-linked inhibitor of apoptosis-deficient male patients and female symptomatic carriers.
    Aguilar C; Lenoir C; Lambert N; Bègue B; Brousse N; Canioni D; Berrebi D; Roy M; Gérart S; Chapel H; Schwerd T; Siproudhis L; Schäppi M; Al-Ahmari A; Mori M; Yamaide A; Galicier L; Neven B; Routes J; Uhlig HH; Koletzko S; Patel S; Kanegane H; Picard C; Fischer A; Bensussan NC; Ruemmele F; Hugot JP; Latour S
    J Allergy Clin Immunol; 2014 Nov; 134(5):1131-41.e9. PubMed ID: 24942515
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of Cell Death and Immunity by XIAP.
    Jost PJ; Vucic D
    Cold Spring Harb Perspect Biol; 2020 Aug; 12(8):. PubMed ID: 31843992
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains.
    Abbott DW; Yang Y; Hutti JE; Madhavarapu S; Kelliher MA; Cantley LC
    Mol Cell Biol; 2007 Sep; 27(17):6012-25. PubMed ID: 17562858
    [TBL] [Abstract][Full Text] [Related]  

  • 12. RIPK2 NODs to XIAP and IBD.
    Topal Y; Gyrd-Hansen M
    Semin Cell Dev Biol; 2021 Jan; 109():144-150. PubMed ID: 32631784
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Postbiotics for NOD2 require nonhematopoietic RIPK2 to improve blood glucose and metabolic inflammation in mice.
    Cavallari JF; Barra NG; Foley KP; Lee A; Duggan BM; Henriksbo BD; Anhê FF; Ashkar AA; Schertzer JD
    Am J Physiol Endocrinol Metab; 2020 Apr; 318(4):E579-E585. PubMed ID: 32101030
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.
    Bertrand MJ; Doiron K; Labbé K; Korneluk RG; Barker PA; Saleh M
    Immunity; 2009 Jun; 30(6):789-801. PubMed ID: 19464198
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A discrete ubiquitin-mediated network regulates the strength of NOD2 signaling.
    Tigno-Aranjuez JT; Bai X; Abbott DW
    Mol Cell Biol; 2013 Jan; 33(1):146-58. PubMed ID: 23109427
    [TBL] [Abstract][Full Text] [Related]  

  • 16. OTULIN restricts Met1-linked ubiquitination to control innate immune signaling.
    Fiil BK; Damgaard RB; Wagner SA; Keusekotten K; Fritsch M; Bekker-Jensen S; Mailand N; Choudhary C; Komander D; Gyrd-Hansen M
    Mol Cell; 2013 Jun; 50(6):818-830. PubMed ID: 23806334
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The inositol phosphatase SHIP-1 inhibits NOD2-induced NF-κB activation by disturbing the interaction of XIAP with RIP2.
    Condé C; Rambout X; Lebrun M; Lecat A; Di Valentin E; Dequiedt F; Piette J; Gloire G; Legrand S
    PLoS One; 2012; 7(7):e41005. PubMed ID: 22815893
    [TBL] [Abstract][Full Text] [Related]  

  • 18. XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures.
    Ellwanger K; Briese S; Arnold C; Kienes I; Heim V; Nachbur U; Kufer TA
    Life Sci Alliance; 2019 Aug; 2(4):. PubMed ID: 31350258
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inflammation NODs to Antagonists of RIP2-XIAP Interaction.
    Xia S; Fu TM; Wu H
    Mol Cell; 2018 Feb; 69(4):535-536. PubMed ID: 29452633
    [TBL] [Abstract][Full Text] [Related]  

  • 20. XIAP regulates cytosol-specific innate immunity to Listeria infection.
    Bauler LD; Duckett CS; O'Riordan MX
    PLoS Pathog; 2008 Aug; 4(8):e1000142. PubMed ID: 18769721
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.