These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 22608920)

  • 21. Synthesis and evaluation of 17alpha-20E-21-(4-substituted phenyl)-19-norpregna-1,3,5(10),20-tetraene-3,17beta-diols as probes for the estrogen receptor alpha hormone binding domain.
    Hanson RN; Lee CY; Friel CJ; Dilis R; Hughes A; DeSombre ER
    J Med Chem; 2003 Jul; 46(14):2865-76. PubMed ID: 12825929
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Synthesis, antiproliferative activity and estrogen receptor α affinity of novel estradiol-linked platinum(II) complex analogs to carboplatin and oxaliplatin. Potential vector complexes to target estrogen-dependent tissues.
    Saha P; Descôteaux C; Brasseur K; Fortin S; Leblanc V; Parent S; Asselin E; Bérubé G
    Eur J Med Chem; 2012 Feb; 48():385-90. PubMed ID: 22209414
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis and evaluation of 17alpha-arylestradiols as ligands for estrogen receptor alpha and beta.
    Sedlák D; Novák P; Kotora M; Bartůnek P
    J Med Chem; 2010 May; 53(10):4290-4. PubMed ID: 20408532
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists.
    Stauffer SR; Coletta CJ; Tedesco R; Nishiguchi G; Carlson K; Sun J; Katzenellenbogen BS; Katzenellenbogen JA
    J Med Chem; 2000 Dec; 43(26):4934-47. PubMed ID: 11150164
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression.
    Harrington WR; Sheng S; Barnett DH; Petz LN; Katzenellenbogen JA; Katzenellenbogen BS
    Mol Cell Endocrinol; 2003 Aug; 206(1-2):13-22. PubMed ID: 12943986
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Identification and structure-activity relationships of a novel series of estrogen receptor ligands based on 7-thiabicyclo[2.2.1]hept-2-ene-7-oxide.
    Wang P; Min J; Nwachukwu JC; Cavett V; Carlson KE; Guo P; Zhu M; Zheng Y; Dong C; Katzenellenbogen JA; Nettles KW; Zhou HB
    J Med Chem; 2012 Mar; 55(5):2324-41. PubMed ID: 22283328
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Phenytoin is an estrogen receptor α-selective modulator that interacts with helix 12.
    Fadiel A; Song J; Tivon D; Hamza A; Cardozo T; Naftolin F
    Reprod Sci; 2015 Feb; 22(2):146-55. PubMed ID: 25258361
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Synthesis, structure and biological properties of Z-17alpha-(2-iodovinyl)-11beta-chloromethyl estradiol-17beta (Z-CMIV), a high affinity ligand for the characterization of estrogen receptor-positive tumors.
    Quivy J; Leclercq G; Deblaton M; Henrot P; Velings N; Norberg B; Evrard G; Zeicher M
    J Steroid Biochem Mol Biol; 1996 Sep; 59(1):103-17. PubMed ID: 9009243
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthesis and biologic activities of 11 beta-substituted estradiol as potential antiestrogens.
    Qian XD; Abul-Hajj YJ
    Steroids; 1990 May; 55(5):238-41. PubMed ID: 2360220
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synthesis and biological evaluation of phenolic 4,5-dihydroisoxazoles and 3-hydroxy ketones as estrogen receptor alpha and beta agonists.
    Poutiainen PK; Venäläinen TA; Peräkylä M; Matilainen JM; Väisänen S; Honkakoski P; Laatikainen R; Pulkkinen JT
    Bioorg Med Chem; 2010 May; 18(10):3437-47. PubMed ID: 20430632
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Estrogen receptor α L543A,L544A mutation changes antagonists to agonists, correlating with the ligand binding domain dimerization associated with DNA binding activity.
    Arao Y; Hamilton KJ; Coons LA; Korach KS
    J Biol Chem; 2013 Jul; 288(29):21105-21116. PubMed ID: 23733188
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Estrogen modulates in vitro T cell responses in a concentration- and receptor-dependent manner: effects on intracellular molecular targets and antioxidant enzymes.
    Priyanka HP; Krishnan HC; Singh RV; Hima L; Thyagarajan S
    Mol Immunol; 2013 Dec; 56(4):328-39. PubMed ID: 23911387
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis and evaluation of isomeric (17alpha,20E)-11beta-methoxy-21-(trifluoromethylphenyl)-19-norpregna-1,3,5(10),20-tetraene-3,17beta-diols as ERalpha-hormone binding domain ligands: effect of the methoxy group on receptor binding and uterotrophic growth.
    Hanson RN; Tongcharoensirikul P; Dilis R; Hughes A; Desombre ER
    J Med Chem; 2007 Feb; 50(3):472-9. PubMed ID: 17266199
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design, synthesis, cytocidal activity and estrogen receptor α affinity of doxorubicin conjugates at 16α-position of estrogen for site-specific treatment of estrogen receptor positive breast cancer.
    Saha P; Fortin S; Leblanc V; Parent S; Asselin É; Bérubé G
    Steroids; 2012 Sep; 77(11):1113-22. PubMed ID: 22801351
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification of coregulators influenced by estrogen receptor subtype specific binding of the ER antagonists 4-hydroxytamoxifen and fulvestrant.
    Evers NM; Wang S; van den Berg JH; Houtman R; Melchers D; de Haan LH; Ederveen AG; Groten JP; Rietjens IM
    Chem Biol Interact; 2014 Sep; 220():222-30. PubMed ID: 25014417
    [TBL] [Abstract][Full Text] [Related]  

  • 36. 16 beta-([18F]fluoro)estrogens: systematic investigation of a new series of fluorine-18-labeled estrogens as potential imaging agents for estrogen-receptor-positive breast tumors.
    VanBrocklin HF; Carlson KE; Katzenellenbogen JA; Welch MJ
    J Med Chem; 1993 May; 36(11):1619-29. PubMed ID: 7684451
    [TBL] [Abstract][Full Text] [Related]  

  • 37. 18F-labeled difluoroestradiols: preparation and preclinical evaluation as estrogen receptor-binding radiopharmaceuticals.
    Seimbille Y; Rousseau J; Bénard F; Morin C; Ali H; Avvakumov G; Hammond GL; van Lier JE
    Steroids; 2002 Aug; 67(9):765-75. PubMed ID: 12123788
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Estrogen receptor subtype-selective ligands: asymmetric synthesis and biological evaluation of cis- and trans-5,11-dialkyl- 5,6,11, 12-tetrahydrochrysenes.
    Meyers MJ; Sun J; Carlson KE; Katzenellenbogen BS; Katzenellenbogen JA
    J Med Chem; 1999 Jul; 42(13):2456-68. PubMed ID: 10395487
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Design, synthesis, and estrogenic activity of a novel estrogen receptor modulator--a hybrid structure of 17beta-estradiol and vitamin E in hippocampal neurons.
    Zhao L; Jin C; Mao Z; Gopinathan MB; Rehder K; Brinton RD
    J Med Chem; 2007 Sep; 50(18):4471-81. PubMed ID: 17696335
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis, antitumor activity and structure-activity studies of novel pyridoxine-based bioisosteric analogs of estradiol.
    Pugachev MV; Pavelyev RS; Nguyen TNT; Gabbasova RR; Bulatov TM; Iksanova AG; Aljondi B; Bondar OV; Grishaev DY; Yamaleeva ZR; Kataeva ON; Nikishova TV; Balakin KV; Shtyrlin YG
    Bioorg Med Chem; 2021 Jan; 30():115957. PubMed ID: 33373820
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.