BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

379 related articles for article (PubMed ID: 2260966)

  • 1. A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens.
    Veldscholte J; Ris-Stalpers C; Kuiper GG; Jenster G; Berrevoets C; Claassen E; van Rooij HC; Trapman J; Brinkmann AO; Mulder E
    Biochem Biophys Res Commun; 1990 Dec; 173(2):534-40. PubMed ID: 2260966
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The androgen receptor in LNCaP cells contains a mutation in the ligand binding domain which affects steroid binding characteristics and response to antiandrogens.
    Veldscholte J; Berrevoets CA; Ris-Stalpers C; Kuiper GG; Jenster G; Trapman J; Brinkmann AO; Mulder E
    J Steroid Biochem Mol Biol; 1992 Mar; 41(3-8):665-9. PubMed ID: 1562539
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Anti-androgens and the mutated androgen receptor of LNCaP cells: differential effects on binding affinity, heat-shock protein interaction, and transcription activation.
    Veldscholte J; Berrevoets CA; Brinkmann AO; Grootegoed JA; Mulder E
    Biochemistry; 1992 Mar; 31(8):2393-9. PubMed ID: 1540595
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unusual specificity of the androgen receptor in the human prostate tumor cell line LNCaP: high affinity for progestagenic and estrogenic steroids.
    Veldscholte J; Voorhorst-Ogink MM; Bolt-de Vries J; van Rooij HC; Trapman J; Mulder E
    Biochim Biophys Acta; 1990 Apr; 1052(1):187-94. PubMed ID: 2322591
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hormonal regulation of prostate-specific antigen (PSA) glycoprotein in the human prostatic adenocarcinoma cell line, LNCaP.
    Montgomery BT; Young CY; Bilhartz DL; Andrews PE; Prescott JL; Thompson NF; Tindall DJ
    Prostate; 1992; 21(1):63-73. PubMed ID: 1379363
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pregnenolone stimulates LNCaP prostate cancer cell growth via the mutated androgen receptor.
    Grigoryev DN; Long BJ; Njar VC; Brodie AH
    J Steroid Biochem Mol Biol; 2000 Dec; 75(1):1-10. PubMed ID: 11179903
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone.
    Culig Z; Hobisch A; Cronauer MV; Cato AC; Hittmair A; Radmayr C; Eberle J; Bartsch G; Klocker H
    Mol Endocrinol; 1993 Dec; 7(12):1541-50. PubMed ID: 8145761
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression and function of normal and LNCaP androgen receptors in androgen-insensitive human prostatic cancer cells. Altered hormone and antihormone specificity in gene transactivation.
    Kokontis J; Ito K; Hiipakka RA; Liao S
    Receptor; 1991; 1(4):271-9. PubMed ID: 1668832
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Androgens stimulate fatty acid synthase in the human prostate cancer cell line LNCaP.
    Swinnen JV; Esquenet M; Goossens K; Heyns W; Verhoeven G
    Cancer Res; 1997 Mar; 57(6):1086-90. PubMed ID: 9067276
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of growth of LNCaP human prostate tumor cells by growth factors and steroid hormones.
    Schuurmans AL; Bolt J; Veldscholte J; Mulder E
    J Steroid Biochem Mol Biol; 1991; 40(1-3):193-7. PubMed ID: 1958520
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of steroid glucuronosyltransferase activities and transcripts by androgen in the human prostatic cancer LNCaP cell line.
    Guillemette C; Hum DW; BĂ©langer A
    Endocrinology; 1996 Jul; 137(7):2872-9. PubMed ID: 8770908
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The androgen receptor: functional structure and expression in transplanted human prostate tumors and prostate tumor cell lines.
    Trapman J; Ris-Stalpers C; van der Korput JA; Kuiper GG; Faber PW; Romijn JC; Mulder E; Brinkmann AO
    J Steroid Biochem Mol Biol; 1990 Dec; 37(6):837-42. PubMed ID: 2285596
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of FGF8 expression by the androgen receptor in human prostate cancer.
    Gnanapragasam VJ; Robson CN; Neal DE; Leung HY
    Oncogene; 2002 Aug; 21(33):5069-80. PubMed ID: 12140757
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Threonine on amino acid position 868 in the human androgen receptor is essential for androgen binding specificity and functional activity.
    Ris-Stalpers C; Verleun-Mooijman MC; Trapman J; Brinkmann AO
    Biochem Biophys Res Commun; 1993 Oct; 196(1):173-80. PubMed ID: 8216289
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Androgen receptor-mediated growth and epidermal growth factor receptor induction in the human prostate cell line LNCaP.
    Schuurmans AL; Bolt J; Mulder E
    Urol Int; 1989; 44(2):71-6. PubMed ID: 2728128
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dehydroepiandrosterone activates mutant androgen receptors expressed in the androgen-dependent human prostate cancer xenograft CWR22 and LNCaP cells.
    Tan J; Sharief Y; Hamil KG; Gregory CW; Zang DY; Sar M; Gumerlock PH; deVere White RW; Pretlow TG; Harris SE; Wilson EM; Mohler JL; French FS
    Mol Endocrinol; 1997 Apr; 11(4):450-9. PubMed ID: 9092797
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The promoter of the prostate-specific antigen gene contains a functional androgen responsive element.
    Riegman PH; Vlietstra RJ; van der Korput JA; Brinkmann AO; Trapman J
    Mol Endocrinol; 1991 Dec; 5(12):1921-30. PubMed ID: 1724287
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Frequent detection of codon 877 mutation in the androgen receptor gene in advanced prostate cancers.
    Gaddipati JP; McLeod DG; Heidenberg HB; Sesterhenn IA; Finger MJ; Moul JW; Srivastava S
    Cancer Res; 1994 Jun; 54(11):2861-4. PubMed ID: 8187068
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of two mutant androgen receptors from human prostatic carcinoma by adrenal androgens and metabolic derivatives of testosterone.
    Culig Z; Stober J; Gast A; Peterziel H; Hobisch A; Radmayr C; Hittmair A; Bartsch G; Cato AC; Klocker H
    Cancer Detect Prev; 1996; 20(1):68-75. PubMed ID: 8907206
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Androgens, antiandrogens and androgen receptor abnormalities.
    Kuil CW; Brinkmann AO
    Eur Urol; 1996; 29 Suppl 2():78-82. PubMed ID: 8717468
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.