These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 22615293)

  • 1. An integrated approach for identification and target validation of antifungal compounds active against Erg11p.
    Hoepfner D; Karkare S; Helliwell SB; Pfeifer M; Trunzer M; De Bonnechose S; Zimmerlin A; Tao J; Richie D; Hofmann A; Reinker S; Frederiksen M; Movva NR; Porter JA; Ryder NS; Parker CN
    Antimicrob Agents Chemother; 2012 Aug; 56(8):4233-40. PubMed ID: 22615293
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus.
    Parker JE; Merkamm M; Manning NJ; Pompon D; Kelly SL; Kelly DE
    Antimicrob Agents Chemother; 2008 Oct; 52(10):3597-603. PubMed ID: 18694951
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A newly identified amino acid substitution T123I in the 14α-demethylase (Erg11p) of Candida albicans confers azole resistance.
    Wu Y; Gao N; Li C; Gao J; Ying C
    FEMS Yeast Res; 2017 May; 17(3):. PubMed ID: 28334124
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Aspergillus fumigatus Damage Resistance Protein Family Coordinately Regulates Ergosterol Biosynthesis and Azole Susceptibility.
    Song J; Zhai P; Zhang Y; Zhang C; Sang H; Han G; Keller NP; Lu L
    mBio; 2016 Feb; 7(1):e01919-15. PubMed ID: 26908577
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Impact of Homologous Resistance Mutations from Pathogenic Yeast on Saccharomyces cerevisiae Lanosterol 14α-Demethylase.
    Sagatova AA; Keniya MV; Tyndall JDA; Monk BC
    Antimicrob Agents Chemother; 2018 Mar; 62(3):. PubMed ID: 29263059
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activity of Isavuconazole and Other Azoles against Candida Clinical Isolates and Yeast Model Systems with Known Azole Resistance Mechanisms.
    Sanglard D; Coste AT
    Antimicrob Agents Chemother; 2016 Jan; 60(1):229-38. PubMed ID: 26482310
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amino acid substitutions in Erg11p of azole-resistant Candida glabrata: Possible effective substitutions and homology modelling.
    Nabili M; Abdollahi Gohar A; Badali H; Mohammadi R; Moazeni M
    J Glob Antimicrob Resist; 2016 Jun; 5():42-6. PubMed ID: 27436465
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Surface-active fungicidal D-peptide inhibitors of the plasma membrane proton pump that block azole resistance.
    Monk BC; Niimi K; Lin S; Knight A; Kardos TB; Cannon RD; Parshot R; King A; Lun D; Harding DR
    Antimicrob Agents Chemother; 2005 Jan; 49(1):57-70. PubMed ID: 15616276
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular modelling of lanosterol 14 alpha-demethylase (CYP51) from Saccharomyces cerevisiae via homology with CYP102, a unique bacterial cytochrome P450 isoform: quantitative structure-activity relationships (QSARs) within two related series of antifungal azole derivatives.
    Lewis DF; Wiseman A; Tarbit MH
    J Enzyme Inhib; 1999; 14(3):175-92. PubMed ID: 10445042
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Use of a yeast-based membrane protein expression technology to overexpress drug resistance efflux pumps.
    Lamping E; Cannon RD
    Methods Mol Biol; 2010; 666():219-50. PubMed ID: 20717788
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Vacuolar Sequestration of Azoles, a Novel Strategy of Azole Antifungal Resistance Conserved across Pathogenic and Nonpathogenic Yeast.
    Khandelwal NK; Wasi M; Nair R; Gupta M; Kumar M; Mondal AK; Gaur NA; Prasad R
    Antimicrob Agents Chemother; 2019 Mar; 63(3):. PubMed ID: 30642932
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei.
    Lamping E; Ranchod A; Nakamura K; Tyndall JD; Niimi K; Holmes AR; Niimi M; Cannon RD
    Antimicrob Agents Chemother; 2009 Feb; 53(2):354-69. PubMed ID: 19015352
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification and evaluation of novel acetolactate synthase inhibitors as antifungal agents.
    Richie DL; Thompson KV; Studer C; Prindle VC; Aust T; Riedl R; Estoppey D; Tao J; Sexton JA; Zabawa T; Drumm J; Cotesta S; Eichenberger J; Schuierer S; Hartmann N; Movva NR; Tallarico JA; Ryder NS; Hoepfner D
    Antimicrob Agents Chemother; 2013 May; 57(5):2272-80. PubMed ID: 23478965
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Relationship between antifungal resistance of fluconazole resistant Candida albicans and mutations in ERG11 gene.
    Feng LJ; Wan Z; Wang XH; Li RY; Liu W
    Chin Med J (Engl); 2010 Mar; 123(5):544-8. PubMed ID: 20367978
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of iron homeostasis mediated by the heme-binding protein Dap1 (damage resistance protein 1) via the P450 protein Erg11/Cyp51.
    Craven RJ; Mallory JC; Hand RA
    J Biol Chem; 2007 Dec; 282(50):36543-51. PubMed ID: 17954932
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Azole resistance in Candida spp].
    Kakeya H; Miyazaki T; Miyazaki Y; Kohno S
    Nihon Ishinkin Gakkai Zasshi; 2003; 44(2):87-92. PubMed ID: 12748589
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modulation of the antifungal activity of new medicinal plant extracts active on Candida glabrata by the major transporters and regulators of the pleiotropic drug-resistance network in Saccharomyces cerevisiae.
    Kolaczkowski M; Kolaczkowska A; Stermitz FR
    Microb Drug Resist; 2009 Mar; 15(1):11-7. PubMed ID: 19216644
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Improved model of lanosterol 14alpha-demethylase by ligand-supported homology modeling: validation by virtual screening and azole optimization.
    Sheng C; Wang W; Che X; Dong G; Wang S; Ji H; Miao Z; Yao J; Zhang W
    ChemMedChem; 2010 Mar; 5(3):390-7. PubMed ID: 20157915
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Limited
    Healey KR; Kordalewska M; Jiménez Ortigosa C; Singh A; Berrío I; Chowdhary A; Perlin DS
    Antimicrob Agents Chemother; 2018 Oct; 62(10):. PubMed ID: 30082281
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Facultative sterol uptake in an ergosterol-deficient clinical isolate of Candida glabrata harboring a missense mutation in ERG11 and exhibiting cross-resistance to azoles and amphotericin B.
    Hull CM; Parker JE; Bader O; Weig M; Gross U; Warrilow AG; Kelly DE; Kelly SL
    Antimicrob Agents Chemother; 2012 Aug; 56(8):4223-32. PubMed ID: 22615281
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.