306 related articles for article (PubMed ID: 22615413)
1. Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity.
Cowell IG; Sondka Z; Smith K; Lee KC; Manville CM; Sidorczuk-Lesthuruge M; Rance HA; Padget K; Jackson GH; Adachi N; Austin CA
Proc Natl Acad Sci U S A; 2012 Jun; 109(23):8989-94. PubMed ID: 22615413
[TBL] [Abstract][Full Text] [Related]
2. Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation.
Lovett BD; Lo Nigro L; Rappaport EF; Blair IA; Osheroff N; Zheng N; Megonigal MD; Williams WR; Nowell PC; Felix CA
Proc Natl Acad Sci U S A; 2001 Aug; 98(17):9802-7. PubMed ID: 11493704
[TBL] [Abstract][Full Text] [Related]
3. Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing.
Whitmarsh RJ; Saginario C; Zhuo Y; Hilgenfeld E; Rappaport EF; Megonigal MD; Carroll M; Liu M; Osheroff N; Cheung NK; Slater DJ; Ried T; Knutsen T; Blair IA; Felix CA
Oncogene; 2003 Nov; 22(52):8448-59. PubMed ID: 14627986
[TBL] [Abstract][Full Text] [Related]
4. The broken MLL gene is frequently located outside the inherent chromosome territory in human lymphoid cells treated with DNA topoisomerase II poison etoposide.
Glukhov SI; Rubtsov MA; Alexeyevsky DA; Alexeevski AV; Razin SV; Iarovaia OV
PLoS One; 2013; 8(9):e75871. PubMed ID: 24086652
[TBL] [Abstract][Full Text] [Related]
5. Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites.
Broeker PL; Super HG; Thirman MJ; Pomykala H; Yonebayashi Y; Tanabe S; Zeleznik-Le N; Rowley JD
Blood; 1996 Mar; 87(5):1912-22. PubMed ID: 8634439
[TBL] [Abstract][Full Text] [Related]
6. Molecular analysis of 13 cases of MLL/11q23 secondary acute leukemia and identification of topoisomerase II consensus-binding sequences near the chromosomal breakpoint of a secondary leukemia with the t(4;11).
Domer PH; Head DR; Renganathan N; Raimondi SC; Yang E; Atlas M
Leukemia; 1995 Aug; 9(8):1305-12. PubMed ID: 7643617
[TBL] [Abstract][Full Text] [Related]
7. Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints.
Lovett BD; Strumberg D; Blair IA; Pang S; Burden DA; Megonigal MD; Rappaport EF; Rebbeck TR; Osheroff N; Pommier YG; Felix CA
Biochemistry; 2001 Feb; 40(5):1159-70. PubMed ID: 11170441
[TBL] [Abstract][Full Text] [Related]
8. An in vivo topoisomerase II cleavage site and a DNase I hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region.
Strissel PL; Strick R; Rowley JD; Zeleznik-Le NJ
Blood; 1998 Nov; 92(10):3793-803. PubMed ID: 9808573
[TBL] [Abstract][Full Text] [Related]
9. Nucleotide-resolution mapping of topoisomerase-mediated and apoptotic DNA strand scissions at or near an MLL translocation hotspot.
Mirault ME; Boucher P; Tremblay A
Am J Hum Genet; 2006 Nov; 79(5):779-91. PubMed ID: 17033956
[TBL] [Abstract][Full Text] [Related]
10. Therapy-related acute myeloid leukemia-like MLL rearrangements are induced by etoposide in primary human CD34+ cells and remain stable after clonal expansion.
Libura J; Slater DJ; Felix CA; Richardson C
Blood; 2005 Mar; 105(5):2124-31. PubMed ID: 15528316
[TBL] [Abstract][Full Text] [Related]
11. Recurrent Translocations in Topoisomerase Inhibitor-Related Leukemia Are Determined by the Features of DNA Breaks Rather Than by the Proximity of the Translocating Genes.
Lomov NA; Viushkov VS; Ulianov SV; Gavrilov AA; Alexeyevsky DA; Artemov AV; Razin SV; Rubtsov MA
Int J Mol Sci; 2022 Aug; 23(17):. PubMed ID: 36077220
[TBL] [Abstract][Full Text] [Related]
12. Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: new insights and new questions.
Sung PA; Libura J; Richardson C
DNA Repair (Amst); 2006 Sep; 5(9-10):1109-18. PubMed ID: 16809075
[TBL] [Abstract][Full Text] [Related]
13. Secondary leukemias induced by topoisomerase-targeted drugs.
Felix CA
Biochim Biophys Acta; 1998 Oct; 1400(1-3):233-55. PubMed ID: 9748598
[TBL] [Abstract][Full Text] [Related]
14. Chromatin structural elements and chromosomal translocations in leukemia.
Zhang Y; Rowley JD
DNA Repair (Amst); 2006 Sep; 5(9-10):1282-97. PubMed ID: 16893685
[TBL] [Abstract][Full Text] [Related]
15. All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders.
Rowley JD; Reshmi S; Sobulo O; Musvee T; Anastasi J; Raimondi S; Schneider NR; Barredo JC; Cantu ES; Schlegelberger B; Behm F; Doggett NA; Borrow J; Zeleznik-Le N
Blood; 1997 Jul; 90(2):535-41. PubMed ID: 9226152
[TBL] [Abstract][Full Text] [Related]
16. Identification of complex genomic breakpoint junctions in the t(9;11) MLL-AF9 fusion gene in acute leukemia.
Super HG; Strissel PL; Sobulo OM; Burian D; Reshmi SC; Roe B; Zeleznik-Le NJ; Diaz MO; Rowley JD
Genes Chromosomes Cancer; 1997 Oct; 20(2):185-95. PubMed ID: 9331569
[TBL] [Abstract][Full Text] [Related]
17. Bioflavonoids promote stable translocations between MLL-AF9 breakpoint cluster regions independent of normal chromosomal context: Model system to screen environmental risks.
Bariar B; Vestal CG; Deem B; Goodenow D; Ughetta M; Engledove RW; Sahyouni M; Richardson C
Environ Mol Mutagen; 2019 Mar; 60(2):154-167. PubMed ID: 30387535
[TBL] [Abstract][Full Text] [Related]
18. MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisomerase II cleavage site.
Slater DJ; Hilgenfeld E; Rappaport EF; Shah N; Meek RG; Williams WR; Lovett BD; Osheroff N; Autar RS; Ried T; Felix CA
Oncogene; 2002 Jul; 21(30):4706-14. PubMed ID: 12096348
[TBL] [Abstract][Full Text] [Related]
19. Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: almost identical MLL breakpoints in therapy-related AML after treatment without etoposides.
Langer T; Metzler M; Reinhardt D; Viehmann S; Borkhardt A; Reichel M; Stanulla M; Schrappe M; Creutzig U; Ritter J; Leis T; Jacobs U; Harbott J; Beck JD; Rascher W; Repp R
Genes Chromosomes Cancer; 2003 Apr; 36(4):393-401. PubMed ID: 12619163
[TBL] [Abstract][Full Text] [Related]
20. DNA topoisomerase II in therapy-related acute promyelocytic leukemia.
Mistry AR; Felix CA; Whitmarsh RJ; Mason A; Reiter A; Cassinat B; Parry A; Walz C; Wiemels JL; Segal MR; Adès L; Blair IA; Osheroff N; Peniket AJ; Lafage-Pochitaloff M; Cross NC; Chomienne C; Solomon E; Fenaux P; Grimwade D
N Engl J Med; 2005 Apr; 352(15):1529-38. PubMed ID: 15829534
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
