These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 22616003)

  • 1. Pretubulysin: from hypothetical biosynthetic intermediate to potential lead in tumor therapy.
    Herrmann J; Elnakady YA; Wiedmann RM; Ullrich A; Rohde M; Kazmaier U; Vollmar AM; Müller R
    PLoS One; 2012; 7(5):e37416. PubMed ID: 22616003
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Simplified pretubulysin derivatives and their biological effects on cancer cells.
    Kubisch R; von Gamm M; Braig S; Ullrich A; Burkhart JL; Colling L; Hermann J; Scherer O; Müller R; Werz O; Kazmaier U; Vollmar AM
    J Nat Prod; 2014 Mar; 77(3):536-42. PubMed ID: 24437936
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Anti-angiogenic effects of the tubulysin precursor pretubulysin and of simplified pretubulysin derivatives.
    Rath S; Liebl J; Fürst R; Ullrich A; Burkhart JL; Kazmaier U; Herrmann J; Müller R; Günther M; Schreiner L; Wagner E; Vollmar AM; Zahler S
    Br J Pharmacol; 2012 Nov; 167(5):1048-61. PubMed ID: 22595030
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pretubulysin, a potent and chemically accessible tubulysin precursor from Angiococcus disciformis.
    Ullrich A; Chai Y; Pistorius D; Elnakady YA; Herrmann JE; Weissman KJ; Kazmaier U; Müller R
    Angew Chem Int Ed Engl; 2009; 48(24):4422-5. PubMed ID: 19431172
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and antitumor activity evaluation of pretubulysin analogs.
    Xu X; Fan M; Qi J; Yao L
    Chem Biol Drug Des; 2021 Sep; 98(3):341-351. PubMed ID: 33930251
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pretubulysin: a new option for the treatment of metastatic cancer.
    Braig S; Wiedmann RM; Liebl J; Singer M; Kubisch R; Schreiner L; Abhari BA; Wagner E; Kazmaier U; Fulda S; Vollmar AM
    Cell Death Dis; 2014 Jan; 5(1):e1001. PubMed ID: 24434509
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biological evaluation of tubulysin A: a potential anticancer and antiangiogenic natural product.
    Kaur G; Hollingshead M; Holbeck S; Schauer-Vukasinović V; Camalier RF; Dömling A; Agarwal S
    Biochem J; 2006 Jun; 396(2):235-42. PubMed ID: 16489930
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The molecular pharmacology of symplostatin 1: a new antimitotic dolastatin 10 analog.
    Mooberry SL; Leal RM; Tinley TL; Luesch H; Moore RE; Corbett TH
    Int J Cancer; 2003 Apr; 104(4):512-21. PubMed ID: 12584751
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism of action of tubulysin, an antimitotic peptide from myxobacteria.
    Khalil MW; Sasse F; Lünsdorf H; Elnakady YA; Reichenbach H
    Chembiochem; 2006 Apr; 7(4):678-83. PubMed ID: 16491500
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pretubulysin derived probes as novel tools for monitoring the microtubule network via activity-based protein profiling and fluorescence microscopy.
    Eirich J; Burkhart JL; Ullrich A; Rudolf GC; Vollmar A; Zahler S; Kazmaier U; Sieber SA
    Mol Biosyst; 2012 Aug; 8(8):2067-75. PubMed ID: 22722320
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 3-(Iodoacetamido)-benzoylurea: a novel cancericidal tubulin ligand that inhibits microtubule polymerization, phosphorylates bcl-2, and induces apoptosis in tumor cells.
    Jiang JD; Davis AS; Middleton K; Ling YH; Perez-Soler R; Holland JF; Bekesi JG
    Cancer Res; 1998 Dec; 58(23):5389-95. PubMed ID: 9850070
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tubulysins, new cytostatic peptides from myxobacteria acting on microtubuli. Production, isolation, physico-chemical and biological properties.
    Sasse F; Steinmetz H; Heil J; Höfle G; Reichenbach H
    J Antibiot (Tokyo); 2000 Sep; 53(9):879-85. PubMed ID: 11099220
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Arsenic trioxide produces polymerization of microtubules and mitotic arrest before apoptosis in human tumor cell lines.
    Ling YH; Jiang JD; Holland JF; Perez-Soler R
    Mol Pharmacol; 2002 Sep; 62(3):529-38. PubMed ID: 12181429
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The tubulysin analogue KEMTUB10 induces apoptosis in breast cancer cells via p53, Bim and Bcl-2.
    Lamidi OF; Sani M; Lazzari P; Zanda M; Fleming IN
    J Cancer Res Clin Oncol; 2015 Sep; 141(9):1575-83. PubMed ID: 25633717
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of 23 natural tubulysins from Angiococcus disciformis An d48 and Cystobacter SBCb004.
    Chai Y; Pistorius D; Ullrich A; Weissman KJ; Kazmaier U; Müller R
    Chem Biol; 2010 Mar; 17(3):296-309. PubMed ID: 20338521
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and Evaluation of Biological Properties of 2-Amino-thiazole-4-carboxamides: Amide Linkage Analogues of Pretubulysin.
    Ouyang B; Wang L; Qi J; Fan M; Wang H; Yao L
    Biol Pharm Bull; 2020; 43(8):1154-1158. PubMed ID: 32741936
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A simplified synthesis of novel dictyostatin analogues with in vitro activity against epothilone B-resistant cells and antiangiogenic activity in zebrafish embryos.
    Vollmer LL; Jiménez M; Camarco DP; Zhu W; Daghestani HN; Balachandran R; Reese CE; Lazo JS; Hukriede NA; Curran DP; Day BW; Vogt A
    Mol Cancer Ther; 2011 Jun; 10(6):994-1006. PubMed ID: 21490306
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential effects of estrone and estrone-3-O-sulfamate derivatives on mitotic. Arrest, apoptosis, and microtubule assembly in human breast cancer cells.
    MacCarthy-Morrogh L; Townsend PA; Purohit A; Hejaz HAM ; Potter BVL ; Reed MJ; Packham G
    Cancer Res; 2000 Oct; 60(19):5441-50. PubMed ID: 11034086
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tubulin-based antimitotic mechanism of E7974, a novel analogue of the marine sponge natural product hemiasterlin.
    Kuznetsov G; TenDyke K; Towle MJ; Cheng H; Liu J; Marsh JP; Schiller SE; Spyvee MR; Yang H; Seletsky BM; Shaffer CJ; Marceau V; Yao Y; Suh EM; Campagna S; Fang FG; Kowalczyk JJ; Littlefield BA
    Mol Cancer Ther; 2009 Oct; 8(10):2852-60. PubMed ID: 19825803
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules.
    Kamath K; Okouneva T; Larson G; Panda D; Wilson L; Jordan MA
    Mol Cancer Ther; 2006 Sep; 5(9):2225-33. PubMed ID: 16985056
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.