274 related articles for article (PubMed ID: 22621786)
1. Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636.
Sbrissa D; Ikonomov OC; Filios C; Delvecchio K; Shisheva A
Am J Physiol Cell Physiol; 2012 Aug; 303(4):C436-46. PubMed ID: 22621786
[TBL] [Abstract][Full Text] [Related]
2. YM201636, an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, halts glucose entry by insulin in adipocytes.
Ikonomov OC; Sbrissa D; Shisheva A
Biochem Biophys Res Commun; 2009 May; 382(3):566-70. PubMed ID: 19289105
[TBL] [Abstract][Full Text] [Related]
3. Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency.
Compton LM; Ikonomov OC; Sbrissa D; Garg P; Shisheva A
Am J Physiol Cell Physiol; 2016 Sep; 311(3):C366-77. PubMed ID: 27335171
[TBL] [Abstract][Full Text] [Related]
4. Role for a novel signaling intermediate, phosphatidylinositol 5-phosphate, in insulin-regulated F-actin stress fiber breakdown and GLUT4 translocation.
Sbrissa D; Ikonomov OC; Strakova J; Shisheva A
Endocrinology; 2004 Nov; 145(11):4853-65. PubMed ID: 15284192
[TBL] [Abstract][Full Text] [Related]
5. Apilimod, a candidate anticancer therapeutic, arrests not only PtdIns(3,5)P2 but also PtdIns5P synthesis by PIKfyve and induces bafilomycin A1-reversible aberrant endomembrane dilation.
Sbrissa D; Naisan G; Ikonomov OC; Shisheva A
PLoS One; 2018; 13(9):e0204532. PubMed ID: 30240452
[TBL] [Abstract][Full Text] [Related]
6. Plentiful PtdIns5P from scanty PtdIns(3,5)P2 or from ample PtdIns? PIKfyve-dependent models: Evidence and speculation (response to: DOI 10.1002/bies.201300012).
Shisheva A; Sbrissa D; Ikonomov O
Bioessays; 2015 Mar; 37(3):267-77. PubMed ID: 25404370
[TBL] [Abstract][Full Text] [Related]
7. ArPIKfyve-PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytes.
Ikonomov OC; Sbrissa D; Dondapati R; Shisheva A
Exp Cell Res; 2007 Jul; 313(11):2404-16. PubMed ID: 17475247
[TBL] [Abstract][Full Text] [Related]
8. PIP5K1C phosphoinositide kinase deficiency distinguishes PIKFYVE-dependent cancer cells from non-malignant cells.
Roy A; Chakraborty AR; Nomanbhoy T; DePamphilis ML
Autophagy; 2023 Sep; 19(9):2464-2484. PubMed ID: 36803256
[TBL] [Abstract][Full Text] [Related]
9. The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- mice.
Ikonomov OC; Sbrissa D; Delvecchio K; Xie Y; Jin JP; Rappolee D; Shisheva A
J Biol Chem; 2011 Apr; 286(15):13404-13. PubMed ID: 21349843
[TBL] [Abstract][Full Text] [Related]
10. PIKfyve inhibitor cytotoxicity requires AKT suppression and excessive cytoplasmic vacuolation.
Ikonomov OC; Altankov G; Sbrissa D; Shisheva A
Toxicol Appl Pharmacol; 2018 Oct; 356():151-158. PubMed ID: 30098992
[TBL] [Abstract][Full Text] [Related]
11. A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding.
Jefferies HB; Cooke FT; Jat P; Boucheron C; Koizumi T; Hayakawa M; Kaizawa H; Ohishi T; Workman P; Waterfield MD; Parker PJ
EMBO Rep; 2008 Feb; 9(2):164-70. PubMed ID: 18188180
[TBL] [Abstract][Full Text] [Related]
12. Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells.
Sbrissa D; Ikonomov OC; Deeb R; Shisheva A
J Biol Chem; 2002 Dec; 277(49):47276-84. PubMed ID: 12270933
[TBL] [Abstract][Full Text] [Related]
13. Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3,5-P2 production for endomembrane integrity.
Ikonomov OC; Sbrissa D; Mlak K; Kanzaki M; Pessin J; Shisheva A
J Biol Chem; 2002 Mar; 277(11):9206-11. PubMed ID: 11714711
[TBL] [Abstract][Full Text] [Related]
14. Essential roles of PIKfyve and PTEN on phagosomal phosphatidylinositol 3-phosphate dynamics.
Hazeki K; Nigorikawa K; Takaba Y; Segawa T; Nukuda A; Masuda A; Ishikawa Y; Kubota K; Takasuga S; Hazeki O
FEBS Lett; 2012 Nov; 586(22):4010-5. PubMed ID: 23068606
[TBL] [Abstract][Full Text] [Related]
15. Small molecule PIKfyve inhibitors as cancer therapeutics: Translational promises and limitations.
Ikonomov OC; Sbrissa D; Shisheva A
Toxicol Appl Pharmacol; 2019 Nov; 383():114771. PubMed ID: 31628917
[TBL] [Abstract][Full Text] [Related]
16. Acquisition of unprecedented phosphatidylinositol 3,5-bisphosphate rise in hyperosmotically stressed 3T3-L1 adipocytes, mediated by ArPIKfyve-PIKfyve pathway.
Sbrissa D; Shisheva A
J Biol Chem; 2005 Mar; 280(9):7883-9. PubMed ID: 15546865
[TBL] [Abstract][Full Text] [Related]
17. Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration.
Oppelt A; Lobert VH; Haglund K; Mackey AM; Rameh LE; Liestøl K; Schink KO; Pedersen NM; Wenzel EM; Haugsten EM; Brech A; Rusten TE; Stenmark H; Wesche J
EMBO Rep; 2013 Jan; 14(1):57-64. PubMed ID: 23154468
[TBL] [Abstract][Full Text] [Related]
18. PIKfyve-Dependent Phosphoinositide Dynamics in Megakaryocyte/Platelet Granule Integrity and Platelet Functions.
Caux M; Mansour R; Xuereb JM; Chicanne G; Viaud J; Vauclard A; Boal F; Payrastre B; Tronchère H; Severin S
Arterioscler Thromb Vasc Biol; 2022 Aug; 42(8):987-1004. PubMed ID: 35708031
[TBL] [Abstract][Full Text] [Related]
19. Requirement for PIKfyve enzymatic activity in acute and long-term insulin cellular effects.
Ikonomov OC; Sbrissa D; Mlak K; Shisheva A
Endocrinology; 2002 Dec; 143(12):4742-54. PubMed ID: 12446602
[TBL] [Abstract][Full Text] [Related]
20. The Lipid Kinase PIKfyve Coordinates the Neutrophil Immune Response through the Activation of the Rac GTPase.
Dayam RM; Sun CX; Choy CH; Mancuso G; Glogauer M; Botelho RJ
J Immunol; 2017 Sep; 199(6):2096-2105. PubMed ID: 28779020
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
