BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 22621930)

  • 1. Identification of residues that confer sugar selectivity to UDP-glycosyltransferase 3A (UGT3A) enzymes.
    Meech R; Rogers A; Zhuang L; Lewis BC; Miners JO; Mackenzie PI
    J Biol Chem; 2012 Jul; 287(29):24122-30. PubMed ID: 22621930
    [TBL] [Abstract][Full Text] [Related]  

  • 2. UDP-Glycosyltransferase 3A Metabolism of Polycyclic Aromatic Hydrocarbons: Potential Importance in Aerodigestive Tract Tissues.
    Vergara AG; Watson CJW; Chen G; Lazarus P
    Drug Metab Dispos; 2020 Mar; 48(3):160-168. PubMed ID: 31836608
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The novel UDP glycosyltransferase 3A2: cloning, catalytic properties, and tissue distribution.
    MacKenzie PI; Rogers A; Elliot DJ; Chau N; Hulin JA; Miners JO; Meech R
    Mol Pharmacol; 2011 Mar; 79(3):472-8. PubMed ID: 21088224
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of UDP glycosyltransferase 3A1 as a UDP N-acetylglucosaminyltransferase.
    Mackenzie PI; Rogers A; Treloar J; Jorgensen BR; Miners JO; Meech R
    J Biol Chem; 2008 Dec; 283(52):36205-10. PubMed ID: 18981171
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insights into the UDP-sugar selectivities of human UDP-glycosyltransferases (UGT): a molecular modeling perspective.
    Nair PC; Meech R; Mackenzie PI; McKinnon RA; Miners JO
    Drug Metab Rev; 2015 Aug; 47(3):335-45. PubMed ID: 26289097
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Catalytic key amino acids and UDP-sugar donor specificity of a plant glucuronosyltransferase, UGT94B1: molecular modeling substantiated by site-specific mutagenesis and biochemical analyses.
    Osmani SA; Bak S; Imberty A; Olsen CE; Møller BL
    Plant Physiol; 2008 Nov; 148(3):1295-308. PubMed ID: 18829982
    [TBL] [Abstract][Full Text] [Related]  

  • 7. UGT3A: novel UDP-glycosyltransferases of the UGT superfamily.
    Meech R; Mackenzie PI
    Drug Metab Rev; 2010 Feb; 42(1):45-54. PubMed ID: 19814657
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular characterization of UDP-glucuronosyltransferases 3A and 8A in cynomolgus macaques.
    Uno Y; Yamazaki H
    Drug Metab Pharmacokinet; 2020 Aug; 35(4):397-400. PubMed ID: 32646660
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Arginine-259 of UGT2B7 Confers UDP-Sugar Selectivity.
    Nair PC; Chau N; McKinnon RA; Miners JO
    Mol Pharmacol; 2020 Dec; 98(6):710-718. PubMed ID: 33008919
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Kinetic basis for the donor nucleotide-sugar specificity of beta1, 4-N-acetylglucosaminyltransferase III.
    Ikeda Y; Koyota S; Ihara H; Yamaguchi Y; Korekane H; Tsuda T; Sasai K; Taniguchi N
    J Biochem; 2000 Oct; 128(4):609-19. PubMed ID: 11011143
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of a residue responsible for UDP-sugar donor selectivity of a dihydroxybenzoic acid glycosyltransferase from Arabidopsis natural accessions.
    Chen HY; Li X
    Plant J; 2017 Jan; 89(2):195-203. PubMed ID: 27411741
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses.
    Thorsøe KS; Bak S; Olsen CE; Imberty A; Breton C; Lindberg Møller B
    Plant Physiol; 2005 Oct; 139(2):664-73. PubMed ID: 16169969
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Engineering flavonoid glycosyltransferases for enhanced catalytic efficiency and extended sugar-donor selectivity.
    Kim HS; Kim BG; Sung S; Kim M; Mok H; Chong Y; Ahn JH
    Planta; 2013 Oct; 238(4):683-93. PubMed ID: 23801300
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparison of human poly-N-acetyl-lactosamine synthase structure with GT-A fold glycosyltransferases supports a modular assembly of catalytic subsites.
    Kadirvelraj R; Yang JY; Kim HW; Sanders JH; Moremen KW; Wood ZA
    J Biol Chem; 2021; 296():100110. PubMed ID: 33229435
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Broaden the sugar donor selectivity of blackberry glycosyltransferase UGT78H2 through residual substitutions.
    Chen Q; Liu X; Hu Y; Wang Y; Sun B; Chen T; Luo Y; Zhang Y; Li M; Liu Z; Wang X; Tang H
    Int J Biol Macromol; 2021 Jan; 166():277-287. PubMed ID: 33129904
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enhanced activity of Withania somnifera family-1 glycosyltransferase (UGT73A16) via mutagenesis.
    Singh S; Patel KA; Sonawane PD; Vishwakarma RK; Khan BM
    World J Microbiol Biotechnol; 2018 Sep; 34(10):150. PubMed ID: 30255239
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Photoaffinity labeling studies of the human recombinant UDP-glucuronosyltransferase, UGT1*6, with 5-azido-UDP-glucuronic acid.
    Battaglia E; Nowell S; Drake RR; Magdalou J; Fournel-Gigleux S; Senay C; Radominska A
    Drug Metab Dispos; 1997 Apr; 25(4):406-11. PubMed ID: 9107538
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural and functional analysis of Campylobacter jejuni PseG: a udp-sugar hydrolase from the pseudaminic acid biosynthetic pathway.
    Rangarajan ES; Proteau A; Cui Q; Logan SM; Potetinova Z; Whitfield D; Purisima EO; Cygler M; Matte A; Sulea T; Schoenhofen IC
    J Biol Chem; 2009 Jul; 284(31):20989-1000. PubMed ID: 19483088
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alteration of human UDP-glucuronosyltransferase UGT2B17 regio-specificity by a single amino acid substitution.
    Dubois SG; Beaulieu M; Lévesque E; Hum DW; Bélanger A
    J Mol Biol; 1999 May; 289(1):29-39. PubMed ID: 10339403
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The donor substrate specificity of the human beta 1,3-glucuronosyltransferase I toward UDP-glucuronic acid is determined by two crucial histidine and arginine residues.
    Ouzzine M; Gulberti S; Levoin N; Netter P; Magdalou J; Fournel-Gigleux S
    J Biol Chem; 2002 Jul; 277(28):25439-45. PubMed ID: 11986319
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.