BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 22628302)

  • 1. Oleic acid is a key cytotoxic component of HAMLET-like complexes.
    Permyakov SE; Knyazeva EL; Khasanova LM; Fadeev RS; Zhadan AP; Roche-Hakansson H; Håkansson AP; Akatov VS; Permyakov EA
    Biol Chem; 2012 Jan; 393(1-2):85-92. PubMed ID: 22628302
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel method for preparation of HAMLET-like protein complexes.
    Permyakov SE; Knyazeva EL; Leonteva MV; Fadeev RS; Chekanov AV; Zhadan AP; Håkansson AP; Akatov VS; Permyakov EA
    Biochimie; 2011 Sep; 93(9):1495-501. PubMed ID: 21596091
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural characterization of more potent alternatives to HAMLET, a tumoricidal complex of α-lactalbumin and oleic acid.
    Nemashkalova EL; Kazakov AS; Khasanova LM; Permyakov EA; Permyakov SE
    Biochemistry; 2013 Sep; 52(36):6286-99. PubMed ID: 23947814
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Who is Mr. HAMLET? Interaction of human alpha-lactalbumin with monomeric oleic acid.
    Knyazeva EL; Grishchenko VM; Fadeev RS; Akatov VS; Permyakov SE; Permyakov EA
    Biochemistry; 2008 Dec; 47(49):13127-37. PubMed ID: 19006329
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure and stability analysis of cytotoxic complex of camel α-lactalbumin and unsaturated fatty acids produced at high temperature.
    Atri MS; Saboury AA; Moosavi-Movahedi AA; Goliaei B; Sefidbakht Y; Alijanvand HH; Sharifzadeh A; Niasari-Naslaji A
    J Biomol Struct Dyn; 2011 Jun; 28(6):919-28. PubMed ID: 21469752
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bovine lactoferrin binds oleic acid to form an anti-tumor complex similar to HAMLET.
    Fang B; Zhang M; Tian M; Jiang L; Guo HY; Ren FZ
    Biochim Biophys Acta; 2014 Apr; 1841(4):535-43. PubMed ID: 24368211
    [TBL] [Abstract][Full Text] [Related]  

  • 7. alpha-Lactalbumin species variation, HAMLET formation, and tumor cell death.
    Pettersson J; Mossberg AK; Svanborg C
    Biochem Biophys Res Commun; 2006 Jun; 345(1):260-70. PubMed ID: 16678133
    [TBL] [Abstract][Full Text] [Related]  

  • 8. alpha-Lactalbumin, engineered to be nonnative and inactive, kills tumor cells when in complex with oleic acid: a new biological function resulting from partial unfolding.
    Pettersson-Kastberg J; Mossberg AK; Trulsson M; Yong YJ; Min S; Lim Y; O'Brien JE; Svanborg C; Mok KH
    J Mol Biol; 2009 Dec; 394(5):994-1010. PubMed ID: 19766653
    [TBL] [Abstract][Full Text] [Related]  

  • 9. α-Lactalbumin forms with oleic acid a high molecular weight complex displaying cytotoxic activity.
    Spolaore B; Pinato O; Canton M; Zambonin M; Polverino de Laureto P; Fontana A
    Biochemistry; 2010 Oct; 49(39):8658-67. PubMed ID: 20804154
    [TBL] [Abstract][Full Text] [Related]  

  • 10. α-Lactalbumin:Oleic Acid Complex Spontaneously Delivers Oleic Acid to Artificial and Erythrocyte Membranes.
    Wen H; Strømland Ø; Halskau Ø
    J Mol Biol; 2015 Sep; 427(19):3177-87. PubMed ID: 26297199
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heat-treatment method for producing fatty acid-bound alpha-lactalbumin that induces tumor cell death.
    Kamijima T; Ohmura A; Sato T; Akimoto K; Itabashi M; Mizuguchi M; Kamiya M; Kikukawa T; Aizawa T; Takahashi M; Kawano K; Demura M
    Biochem Biophys Res Commun; 2008 Nov; 376(1):211-4. PubMed ID: 18774773
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytotoxicity of bovine α-lactalbumin: oleic acid complexes correlates with the disruption of lipid membranes.
    Wen H; Glomm WR; Halskau O
    Biochim Biophys Acta; 2013 Nov; 1828(11):2691-9. PubMed ID: 23916586
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lipids as tumoricidal components of human α-lactalbumin made lethal to tumor cells (HAMLET): unique and shared effects on signaling and death.
    Ho JC; Storm P; Rydström A; Bowen B; Alsin F; Sullivan L; Ambite I; Mok KH; Northen T; Svanborg C
    J Biol Chem; 2013 Jun; 288(24):17460-71. PubMed ID: 23629662
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Electrostatic interactions play an essential role in the binding of oleic acid with α-lactalbumin in the HAMLET-like complex: a study using charge-specific chemical modifications.
    Xie Y; Min S; Harte NP; Kirk H; O'Brien JE; Voorheis HP; Svanborg C; Hun Mok K
    Proteins; 2013 Jan; 81(1):1-17. PubMed ID: 22777854
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular mechanisms of the cytotoxicity of human α-lactalbumin made lethal to tumor cells (HAMLET) and other protein-oleic acid complexes.
    Nakamura T; Aizawa T; Kariya R; Okada S; Demura M; Kawano K; Makabe K; Kuwajima K
    J Biol Chem; 2013 May; 288(20):14408-14416. PubMed ID: 23580643
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A molecular complex of bovine milk protein and oleic acid selectively kills cancer cells in vitro and inhibits tumour growth in an orthotopic rat bladder tumour model.
    Xiao Z; Mak A; Koch K; Moore RB
    BJU Int; 2013 Jul; 112(2):E201-10. PubMed ID: 23356235
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alpha-lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells).
    Svensson M; Fast J; Mossberg AK; Düringer C; Gustafsson L; Hallgren O; Brooks CL; Berliner L; Linse S; Svanborg C
    Protein Sci; 2003 Dec; 12(12):2794-804. PubMed ID: 14627739
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Behaviour of oleic acid-depleted bovine alpha-lactalbumin made LEthal to tumor cells (BAMLET).
    Hoque M; Gupta J; Rabbani G; Khan RH; Saleemuddin M
    Mol Biosyst; 2016 May; 12(6):1871-80. PubMed ID: 27109252
    [TBL] [Abstract][Full Text] [Related]  

  • 19. No need to be HAMLET or BAMLET to interact with histones: binding of monomeric alpha-lactalbumin to histones and basic poly-amino acids.
    Permyakov SE; Pershikova IV; Khokhlova TI; Uversky VN; Permyakov EA
    Biochemistry; 2004 May; 43(19):5575-82. PubMed ID: 15134431
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Divergent Anticancer Activity of Free and Formulated Camel Milk α-Lactalbumin.
    Uversky VN; El-Fakharany EM; Abu-Serie MM; Almehdar HA; Redwan EM
    Cancer Invest; 2017 Oct; 35(9):610-623. PubMed ID: 28949782
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.