BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 22634226)

  • 1. Intermittent PTH (1-34) injection rescues the retarded skeletal development and postnatal lethality of mice mimicking human achondroplasia and thanatophoric dysplasia.
    Xie Y; Su N; Jin M; Qi H; Yang J; Li C; Du X; Luo F; Chen B; Shen Y; Huang H; Xian CJ; Deng C; Chen L
    Hum Mol Genet; 2012 Sep; 21(18):3941-55. PubMed ID: 22634226
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PTH has the potential to rescue disturbed bone growth in achondroplasia.
    Ueda K; Yamanaka Y; Harada D; Yamagami E; Tanaka H; Seino Y
    Bone; 2007 Jul; 41(1):13-8. PubMed ID: 17466614
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Statin treatment rescues FGFR3 skeletal dysplasia phenotypes.
    Yamashita A; Morioka M; Kishi H; Kimura T; Yahara Y; Okada M; Fujita K; Sawai H; Ikegawa S; Tsumaki N
    Nature; 2014 Sep; 513(7519):507-11. PubMed ID: 25231866
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia.
    Naski MC; Wang Q; Xu J; Ornitz DM
    Nat Genet; 1996 Jun; 13(2):233-7. PubMed ID: 8640234
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HDAC6 deficiency or inhibition blocks FGFR3 accumulation and improves bone growth in a model of achondroplasia.
    Ota S; Zhou ZQ; Romero MP; Yang G; Hurlin PJ
    Hum Mol Genet; 2016 Oct; 25(19):4227-4243. PubMed ID: 27506979
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PTHrP rescues ATDC5 cells from apoptosis induced by FGF receptor 3 mutation.
    Yamanaka Y; Tanaka H; Koike M; Nishimura R; Seino Y
    J Bone Miner Res; 2003 Aug; 18(8):1395-403. PubMed ID: 12929929
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Meclozine promotes longitudinal skeletal growth in transgenic mice with achondroplasia carrying a gain-of-function mutation in the FGFR3 gene.
    Matsushita M; Hasegawa S; Kitoh H; Mori K; Ohkawara B; Yasoda A; Masuda A; Ishiguro N; Ohno K
    Endocrinology; 2015 Feb; 156(2):548-54. PubMed ID: 25456072
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FGFR3 promotes synchondrosis closure and fusion of ossification centers through the MAPK pathway.
    Matsushita T; Wilcox WR; Chan YY; Kawanami A; Bükülmez H; Balmes G; Krejci P; Mekikian PB; Otani K; Yamaura I; Warman ML; Givol D; Murakami S
    Hum Mol Genet; 2009 Jan; 18(2):227-40. PubMed ID: 18923003
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PTH 1-34 Ameliorates the Osteopenia and Delayed Healing of Stabilized Tibia Fracture in Mice with Achondroplasia Resulting from Gain-Of-Function Mutation of FGFR3.
    Chen H; Sun X; Yin L; Chen S; Zhu Y; Huang J; Jiang W; Chen B; Zhang R; Chen L; Nie M; Xie Y; Deng Z
    Int J Biol Sci; 2017; 13(10):1254-1265. PubMed ID: 29104492
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Clinical dosage of meclozine promotes longitudinal bone growth, bone volume, and trabecular bone quality in transgenic mice with achondroplasia.
    Matsushita M; Esaki R; Mishima K; Ishiguro N; Ohno K; Kitoh H
    Sci Rep; 2017 Aug; 7(1):7371. PubMed ID: 28785080
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel FGFR3-binding peptide inhibits FGFR3 signaling and reverses the lethal phenotype of mice mimicking human thanatophoric dysplasia.
    Jin M; Yu Y; Qi H; Xie Y; Su N; Wang X; Tan Q; Luo F; Zhu Y; Wang Q; Du X; Xian CJ; Liu P; Huang H; Shen Y; Deng CX; Chen D; Chen L
    Hum Mol Genet; 2012 Dec; 21(26):5443-55. PubMed ID: 23014564
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Maternal administration of meclozine for the treatment of foramen magnum stenosis in transgenic mice with achondroplasia.
    Matsushita M; Mishima K; Esaki R; Ishiguro N; Ohno K; Kitoh H
    J Neurosurg Pediatr; 2017 Jan; 19(1):91-95. PubMed ID: 27767902
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Common mutations in the fibroblast growth factor receptor 3 (FGFR 3) gene account for achondroplasia, hypochondroplasia, and thanatophoric dwarfism.
    Bonaventure J; Rousseau F; Legeai-Mallet L; Le Merrer M; Munnich A; Maroteaux P
    Am J Med Genet; 1996 May; 63(1):148-54. PubMed ID: 8723101
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Knock-in human FGFR3 achondroplasia mutation as a mouse model for human skeletal dysplasia.
    Lee YC; Song IW; Pai YJ; Chen SD; Chen YT
    Sci Rep; 2017 Feb; 7():43220. PubMed ID: 28230213
    [TBL] [Abstract][Full Text] [Related]  

  • 15. FGFR3 mutation causes abnormal membranous ossification in achondroplasia.
    Di Rocco F; Biosse Duplan M; Heuzé Y; Kaci N; Komla-Ebri D; Munnich A; Mugniery E; Benoist-Lasselin C; Legeai-Mallet L
    Hum Mol Genet; 2014 Jun; 23(11):2914-25. PubMed ID: 24419316
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular basis for the treatment of achondroplasia.
    Yamanaka Y; Ueda K; Seino Y; Tanaka H
    Horm Res; 2003; 60 Suppl 3():60-4. PubMed ID: 14671399
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Ser(365)-->Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia.
    Chen L; Li C; Qiao W; Xu X; Deng C
    Hum Mol Genet; 2001 Mar; 10(5):457-65. PubMed ID: 11181569
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutations causing achondroplasia and thanatophoric dysplasia alter bFGF-induced calcium signals in human diploid fibroblasts.
    Nguyen HB; Estacion M; Gargus JJ
    Hum Mol Genet; 1997 May; 6(5):681-8. PubMed ID: 9158142
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.
    Martin L; Kaci N; Estibals V; Goudin N; Garfa-Traore M; Benoist-Lasselin C; Dambroise E; Legeai-Mallet L
    Hum Mol Genet; 2018 Jan; 27(1):1-13. PubMed ID: 29040558
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Delayed bone age due to a dual effect of FGFR3 mutation in Achondroplasia.
    Pannier S; Mugniery E; Jonquoy A; Benoist-Lasselin C; Odent T; Jais JP; Munnich A; Legeai-Mallet L
    Bone; 2010 Nov; 47(5):905-15. PubMed ID: 20673820
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.