BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

408 related articles for article (PubMed ID: 22634579)

  • 1. Inactivation of PI3K/Akt signaling mediates proliferation inhibition and G2/M phase arrest induced by andrographolide in human glioblastoma cells.
    Li Y; Zhang P; Qiu F; Chen L; Miao C; Li J; Xiao W; Ma E
    Life Sci; 2012 Jun; 90(25-26):962-7. PubMed ID: 22634579
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitory effects of andrographolide on migration and invasion in human non-small cell lung cancer A549 cells via down-regulation of PI3K/Akt signaling pathway.
    Lee YC; Lin HH; Hsu CH; Wang CJ; Chiang TA; Chen JH
    Eur J Pharmacol; 2010 Apr; 632(1-3):23-32. PubMed ID: 20097193
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sinodielide A exerts thermosensitizing effects and induces apoptosis and G2/M cell cycle arrest in DU145 human prostate cancer cells via the Ras/Raf/MAPK and PI3K/Akt signaling pathways.
    Hatashita M; Taniguchi M; Baba K; Koshiba K; Sato T; Jujo Y; Suzuki R; Hayashi S
    Int J Mol Med; 2014 Feb; 33(2):406-14. PubMed ID: 24285252
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Andrographolide reduces proliferation and migration of lens epithelial cells by modulating PI3K/Akt pathway.
    Kayastha F; Madhu H; Vasavada A; Johar K
    Exp Eye Res; 2014 Nov; 128():23-6. PubMed ID: 25220506
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Andrographolide-induced pi class of glutathione S-transferase gene expression via PI3K/Akt pathway in rat primary hepatocytes.
    Lu CY; Li CC; Lii CK; Yao HT; Liu KL; Tsai CW; Chen HW
    Food Chem Toxicol; 2011 Jan; 49(1):281-9. PubMed ID: 21056613
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SRJ23, a new semisynthetic andrographolide derivative: in vitro growth inhibition and mechanisms of cell cycle arrest and apoptosis in prostate cancer cells.
    Wong HC; Wong CC; Sagineedu SR; Loke SC; Lajis NH; Stanslas J
    Cell Biol Toxicol; 2014 Oct; 30(5):269-88. PubMed ID: 25070834
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The novel synthesized 2-(3-(methylamino)phenyl)-6-(pyrrolidin-1-yl)quinolin-4-one (Smh-3) compound induces G2/M phase arrest and mitochondrial-dependent apoptotic cell death through inhibition of CDK1 and AKT activity in HL-60 human leukemia cells.
    Huang SM; Yang JS; Tsai SC; Chen MH; Hsu MH; Lin HY; Chou LC; Chinag JH; Lee KH; Huang LJ; Kuo SC
    Int J Oncol; 2011 May; 38(5):1357-64. PubMed ID: 21344160
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Andrographolide induces cell cycle arrest at G2/M phase and cell death in HepG2 cells via alteration of reactive oxygen species.
    Li J; Cheung HY; Zhang Z; Chan GK; Fong WF
    Eur J Pharmacol; 2007 Jul; 568(1-3):31-44. PubMed ID: 17512926
    [TBL] [Abstract][Full Text] [Related]  

  • 9. M(2)-A induces apoptosis and G(2)-M arrest via inhibiting PI3K/Akt pathway in HL60 cells.
    Wang J; Wu A; Xu Y; Liu J; Qian X
    Cancer Lett; 2009 Oct; 283(2):193-202. PubMed ID: 19435648
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Arsenic trioxide induces apoptosis and G2/M phase arrest by inducing Cbl to inhibit PI3K/Akt signaling and thereby regulate p53 activation.
    Li Y; Qu X; Qu J; Zhang Y; Liu J; Teng Y; Hu X; Hou K; Liu Y
    Cancer Lett; 2009 Nov; 284(2):208-15. PubMed ID: 19457607
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antiproliferative effect of sphingosylphosphorylcholine in thyroid FRO cancer cells mediated by cell cycle arrest in the G2/M phase.
    Afrasiabi E; Blom T; Balthasar S; Törnquist K
    Mol Cell Endocrinol; 2007 Aug; 274(1-2):43-52. PubMed ID: 17606321
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel imidazopyridine PI3K inhibitor with anticancer activity in non-small cell lung cancer cells.
    Lee H; Kim SJ; Jung KH; Son MK; Yan HH; Hong S; Hong SS
    Oncol Rep; 2013 Aug; 30(2):863-9. PubMed ID: 23708425
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways.
    Yang T; Yao S; Zhang X; Guo Y
    Drug Des Devel Ther; 2016; 10():1389-97. PubMed ID: 27114702
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Downregulation of uPA inhibits migration and PI3k/Akt signaling in glioblastoma cells.
    Chandrasekar N; Mohanam S; Gujrati M; Olivero WC; Dinh DH; Rao JS
    Oncogene; 2003 Jan; 22(3):392-400. PubMed ID: 12545160
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The dietary phytochemical 3,3'-diindolylmethane induces G2/M arrest and apoptosis in oral squamous cell carcinoma by modulating Akt-NF-κB, MAPK, and p53 signaling.
    Weng JR; Bai LY; Chiu CF; Wang YC; Tsai MH
    Chem Biol Interact; 2012 Feb; 195(3):224-30. PubMed ID: 22290291
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Induction of G2 /M phase arrest and apoptosis of MCF-7 cells by novel benzofuran lignan via suppressing cell cycle proteins].
    Yang H; Cai YC; Pang JY; Li YQ; Zeng ZL; Xu ZL; Xian LJ
    Yao Xue Xue Bao; 2008 Feb; 43(2):138-44. PubMed ID: 18507339
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Andrographolide suppresses endothelial cell apoptosis via activation of phosphatidyl inositol-3-kinase/Akt pathway.
    Chen JH; Hsiao G; Lee AR; Wu CC; Yen MH
    Biochem Pharmacol; 2004 Apr; 67(7):1337-45. PubMed ID: 15013849
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HS-116, a novel phosphatidylinositol 3-kinase inhibitor induces apoptosis and suppresses angiogenesis of hepatocellular carcinoma through inhibition of the PI3K/AKT/mTOR pathway.
    Jung KH; Choi MJ; Hong S; Lee H; Hong SW; Zheng HM; Lee HS; Hong S; Hong SS
    Cancer Lett; 2012 Mar; 316(2):187-95. PubMed ID: 22182943
    [TBL] [Abstract][Full Text] [Related]  

  • 19. beta-Sitosterol induces G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways.
    Moon DO; Kim MO; Choi YH; Kim GY
    Cancer Lett; 2008 Jun; 264(2):181-91. PubMed ID: 18314257
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal Medicine.
    Zhang FY; Hu Y; Que ZY; Wang P; Liu YH; Wang ZH; Xue YX
    Int J Mol Sci; 2015 Oct; 16(10):23823-48. PubMed ID: 26473829
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.