BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

310 related articles for article (PubMed ID: 22635276)

  • 1. Sumoylation of MDC1 is important for proper DNA damage response.
    Luo K; Zhang H; Wang L; Yuan J; Lou Z
    EMBO J; 2012 Jun; 31(13):3008-19. PubMed ID: 22635276
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ataxin-3 consolidates the MDC1-dependent DNA double-strand break response by counteracting the SUMO-targeted ubiquitin ligase RNF4.
    Pfeiffer A; Luijsterburg MS; Acs K; Wiegant WW; Helfricht A; Herzog LK; Minoia M; Böttcher C; Salomons FA; van Attikum H; Dantuma NP
    EMBO J; 2017 Apr; 36(8):1066-1083. PubMed ID: 28275011
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair.
    Galanty Y; Belotserkovskaya R; Coates J; Jackson SP
    Genes Dev; 2012 Jun; 26(11):1179-95. PubMed ID: 22661229
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage.
    Yin Y; Seifert A; Chua JS; Maure JF; Golebiowski F; Hay RT
    Genes Dev; 2012 Jun; 26(11):1196-208. PubMed ID: 22661230
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RNF4 is required for DNA double-strand break repair in vivo.
    Vyas R; Kumar R; Clermont F; Helfricht A; Kalev P; Sotiropoulou P; Hendriks IA; Radaelli E; Hochepied T; Blanpain C; Sablina A; van Attikum H; Olsen JV; Jochemsen AG; Vertegaal AC; Marine JC
    Cell Death Differ; 2013 Mar; 20(3):490-502. PubMed ID: 23197296
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA damage-induced sumoylation of Sp1 induces its interaction with RNF4 and degradation in S phase to remove 53BP1 from DSBs and permit HR.
    Swift ML; Azizkhan-Clifford J
    DNA Repair (Amst); 2022 Mar; 111():103289. PubMed ID: 35124373
    [TBL] [Abstract][Full Text] [Related]  

  • 7. System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modified Target Proteins and Acceptor Lysines Relevant for Genome Stability.
    Xiao Z; Chang JG; Hendriks IA; Sigurðsson JO; Olsen JV; Vertegaal AC
    Mol Cell Proteomics; 2015 May; 14(5):1419-34. PubMed ID: 25755297
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The direct interaction between 53BP1 and MDC1 is required for the recruitment of 53BP1 to sites of damage.
    Eliezer Y; Argaman L; Rhie A; Doherty AJ; Goldberg M
    J Biol Chem; 2009 Jan; 284(1):426-435. PubMed ID: 18986980
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response.
    Marteijn JA; Bekker-Jensen S; Mailand N; Lans H; Schwertman P; Gourdin AM; Dantuma NP; Lukas J; Vermeulen W
    J Cell Biol; 2009 Sep; 186(6):835-47. PubMed ID: 19797077
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MDC1 is a mediator of the mammalian DNA damage checkpoint.
    Stewart GS; Wang B; Bignell CR; Taylor AM; Elledge SJ
    Nature; 2003 Feb; 421(6926):961-6. PubMed ID: 12607005
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recruitment of proteins to DNA double-strand breaks: MDC1 directly recruits RAP80.
    Strauss C; Goldberg M
    Cell Cycle; 2011 Sep; 10(17):2850-7. PubMed ID: 21857162
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites.
    Pei H; Zhang L; Luo K; Qin Y; Chesi M; Fei F; Bergsagel PL; Wang L; You Z; Lou Z
    Nature; 2011 Feb; 470(7332):124-8. PubMed ID: 21293379
    [TBL] [Abstract][Full Text] [Related]  

  • 13. JMJD1C demethylates MDC1 to regulate the RNF8 and BRCA1-mediated chromatin response to DNA breaks.
    Watanabe S; Watanabe K; Akimov V; Bartkova J; Blagoev B; Lukas J; Bartek J
    Nat Struct Mol Biol; 2013 Dec; 20(12):1425-33. PubMed ID: 24240613
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Recruitment kinetics of DNA repair proteins Mdc1 and Rad52 but not 53BP1 depend on damage complexity.
    Hable V; Drexler GA; Brüning T; Burgdorf C; Greubel C; Derer A; Seel J; Strickfaden H; Cremer T; Friedl AA; Dollinger G
    PLoS One; 2012; 7(7):e41943. PubMed ID: 22860035
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MDC1 is ubiquitylated on its tandem BRCT domain and directly binds RAP80 in a UBC13-dependent manner.
    Strauss C; Halevy T; Macarov M; Argaman L; Goldberg M
    DNA Repair (Amst); 2011 Aug; 10(8):806-14. PubMed ID: 21622030
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Disassembly of MDC1 foci is controlled by ubiquitin-proteasome-dependent degradation.
    Shi W; Ma Z; Willers H; Akhtar K; Scott SP; Zhang J; Powell S; Zhang J
    J Biol Chem; 2008 Nov; 283(46):31608-16. PubMed ID: 18757370
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Three-dimensional imaging reveals the spatial separation of γH2AX-MDC1-53BP1 and RNF8-RNF168-BRCA1-A complexes at ionizing radiation-induced foci.
    Mok MT; Henderson BR
    Radiother Oncol; 2012 Jun; 103(3):415-20. PubMed ID: 22633816
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci.
    Mok MT; Henderson BR
    Int J Biochem Cell Biol; 2012 Sep; 44(9):1398-409. PubMed ID: 22677490
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.
    Kumar R; González-Prieto R; Xiao Z; Verlaan-de Vries M; Vertegaal ACO
    Nat Commun; 2017 Nov; 8(1):1809. PubMed ID: 29180619
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 53BP1 and MDC1 foci formation in HT-1080 cells for low- and high-LET microbeam irradiations.
    Mosconi M; Giesen U; Langner F; Mielke C; Dalla Rosa I; Dirks WG
    Radiat Environ Biophys; 2011 Aug; 50(3):345-52. PubMed ID: 21559952
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.