BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

932 related articles for article (PubMed ID: 22641383)

  • 1. Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.
    Yokosuka T; Takamatsu M; Kobayashi-Imanishi W; Hashimoto-Tane A; Azuma M; Saito T
    J Exp Med; 2012 Jun; 209(6):1201-17. PubMed ID: 22641383
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PD-L2 suppresses T cell signaling via coinhibitory microcluster formation and SHP2 phosphatase recruitment.
    Takehara T; Wakamatsu E; Machiyama H; Nishi W; Emoto K; Azuma M; Soejima K; Fukunaga K; Yokosuka T
    Commun Biol; 2021 May; 4(1):581. PubMed ID: 33990697
    [TBL] [Abstract][Full Text] [Related]  

  • 3. T cell-specific constitutive active SHP2 enhances T cell memory formation and reduces T cell activation.
    Cammann C; Israel N; Frentzel S; Jeron A; Topfstedt E; Schüler T; Simeoni L; Zenker M; Fehling HJ; Schraven B; Bruder D; Seifert U
    Front Immunol; 2022; 13():958616. PubMed ID: 35983034
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PD-1 suppresses TCR-CD8 cooperativity during T-cell antigen recognition.
    Li K; Yuan Z; Lyu J; Ahn E; Davis SJ; Ahmed R; Zhu C
    Nat Commun; 2021 May; 12(1):2746. PubMed ID: 33980853
    [TBL] [Abstract][Full Text] [Related]  

  • 5. T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition.
    Hui E; Cheung J; Zhu J; Su X; Taylor MJ; Wallweber HA; Sasmal DK; Huang J; Kim JM; Mellman I; Vale RD
    Science; 2017 Mar; 355(6332):1428-1433. PubMed ID: 28280247
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Analysis of the role of negative T cell costimulatory pathways in CD4 and CD8 T cell-mediated alloimmune responses in vivo.
    Ito T; Ueno T; Clarkson MR; Yuan X; Jurewicz MM; Yagita H; Azuma M; Sharpe AH; Auchincloss H; Sayegh MH; Najafian N
    J Immunol; 2005 Jun; 174(11):6648-56. PubMed ID: 15905503
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SHP-1 phosphatase activity counteracts increased T cell receptor affinity.
    Hebeisen M; Baitsch L; Presotto D; Baumgaertner P; Romero P; Michielin O; Speiser DE; Rufer N
    J Clin Invest; 2013 Mar; 123(3):1044-56. PubMed ID: 23391724
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2.
    Xu X; Hou B; Fulzele A; Masubuchi T; Zhao Y; Wu Z; Hu Y; Jiang Y; Ma Y; Wang H; Bennett EJ; Fu G; Hui E
    J Cell Biol; 2020 Jun; 219(6):. PubMed ID: 32437509
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evaluation of therapeutic PD-1 antibodies by an advanced single-molecule imaging system detecting human PD-1 microclusters.
    Nishi W; Wakamatsu E; Machiyama H; Matsushima R; Saito K; Yoshida Y; Nishikawa T; Takehara T; Toyota H; Furuhata M; Nishijima H; Takeuchi A; Azuma M; Suzuki M; Yokosuka T
    Nat Commun; 2023 Jun; 14(1):3157. PubMed ID: 37280233
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Programmed death-1 (PD-1):PD-ligand 1 interactions inhibit TCR-mediated positive selection of thymocytes.
    Keir ME; Latchman YE; Freeman GJ; Sharpe AH
    J Immunol; 2005 Dec; 175(11):7372-9. PubMed ID: 16301644
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.
    Tewalt EF; Cohen JN; Rouhani SJ; Guidi CJ; Qiao H; Fahl SP; Conaway MR; Bender TP; Tung KS; Vella AT; Adler AJ; Chen L; Engelhard VH
    Blood; 2012 Dec; 120(24):4772-82. PubMed ID: 22993390
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transforming growth factor beta orchestrates PD-L1 enrichment in tumor-derived exosomes and mediates CD8 T-cell dysfunction regulating early phosphorylation of TCR signalome in breast cancer.
    Chatterjee S; Chatterjee A; Jana S; Dey S; Roy H; Das MK; Alam J; Adhikary A; Chowdhury A; Biswas A; Manna D; Bhattacharyya A
    Carcinogenesis; 2021 Feb; 42(1):38-47. PubMed ID: 32832992
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A quantitative assessment of costimulation and phosphatase activity on microclusters in early T cell signaling.
    Witsenburg JJ; Glauner H; Müller JP; Groenewoud JM; Roth G; Böhmer FD; Adjobo-Hermans MJ; Brock R
    PLoS One; 2013; 8(10):e79277. PubMed ID: 24205378
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular Dynamics of Co-signal Molecules in T-Cell Activation.
    Saito T
    Adv Exp Med Biol; 2019; 1189():135-152. PubMed ID: 31758533
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression regulation and function of PD-1 and PD-L1 in T lymphoma cells.
    Liu MY; Klement JD; Langan CJ; van Riggelen J; Liu K
    Cell Immunol; 2021 Aug; 366():104397. PubMed ID: 34157461
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Blockage of immune checkpoint molecules increases T-cell priming potential of dendritic cell vaccine.
    Hassannia H; Ghasemi Chaleshtari M; Atyabi F; Nosouhian M; Masjedi A; Hojjat-Farsangi M; Namdar A; Azizi G; Mohammadi H; Ghalamfarsa G; Sabz G; Hasanzadeh S; Yousefi M; Jadidi-Niaragh F
    Immunology; 2020 Jan; 159(1):75-87. PubMed ID: 31587253
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2.
    Carter L; Fouser LA; Jussif J; Fitz L; Deng B; Wood CR; Collins M; Honjo T; Freeman GJ; Carreno BM
    Eur J Immunol; 2002 Mar; 32(3):634-43. PubMed ID: 11857337
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Effects of soluble programmed death ligand 1 on regulating the proliferation of T lymphocytes and its mechanism].
    Zhao J; Pan X; Xing Y; Lu M; Chen Y; Shi M
    Zhonghua Yi Xue Za Zhi; 2015 Feb; 95(6):449-52. PubMed ID: 25916783
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular mechanism of SHP2 activation by PD-1 stimulation.
    Marasco M; Berteotti A; Weyershaeuser J; Thorausch N; Sikorska J; Krausze J; Brandt HJ; Kirkpatrick J; Rios P; Schamel WW; Köhn M; Carlomagno T
    Sci Adv; 2020 Jan; 6(5):eaay4458. PubMed ID: 32064351
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Src-homology domain 2-bearing protein tyrosine phosphatase-1 inhibits antigen receptor-induced apoptosis of activated peripheral T cells.
    Zhang J; Somani AK; Watt S; Mills GB; Siminovitch KA
    J Immunol; 1999 Jun; 162(11):6359-67. PubMed ID: 10352248
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 47.