BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

428 related articles for article (PubMed ID: 22645761)

  • 21. Design, synthesis, and biological evaluation of novel 2-ethyl-5-phenylthiazole-4-carboxamide derivatives as protein tyrosine phosphatase 1B inhibitors with improved cellular efficacy.
    Chen YT; Tang CL; Ma WP; Gao LX; Wei Y; Zhang W; Li JY; Li J; Nan FJ
    Eur J Med Chem; 2013 Nov; 69():399-412. PubMed ID: 24090912
    [TBL] [Abstract][Full Text] [Related]  

  • 22. 3-Phenylpropanoic acid-based phosphotyrosine (pTyr) mimetics: hit evolution to a novel orally active protein tyrosine phosphatase 1B (PTP1B) inhibitor.
    Tang YB; Liu JZ; Zhang SE; Du X; Nie F; Tian JY; Ye F; Huang K; Hu JP; Li Y; Xiao Z
    ChemMedChem; 2014 May; 9(5):918-21. PubMed ID: 24644278
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis and biological evaluation of 4,4-dimethyl lithocholic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B.
    He HB; Gao LX; Deng QF; Ma WP; Tang CL; Qiu WW; Tang J; Li JY; Li J; Yang F
    Bioorg Med Chem Lett; 2012 Dec; 22(23):7237-42. PubMed ID: 23067554
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Y-shaped bis-arylethenesulfonic acid esters: Potential potent and membrane permeable protein tyrosine phosphatase 1B inhibitors.
    Yang F; Xie F; Zhang Y; Xia Y; Liu W; Jiang F; Lam C; Qiao Y; Xie D; Li J; Fu L
    Bioorg Med Chem Lett; 2017 May; 27(10):2166-2170. PubMed ID: 28372909
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis and biological evaluation of oleanolic acid derivatives as PTP1B inhibitors.
    Liu QC; Guo TT; Zhang L; Yu Y; Wang P; Yang JF; Li YX
    Eur J Med Chem; 2013 May; 63():511-22. PubMed ID: 23531458
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Synthesis, biological evaluation and 3D-QSAR studies of imidazolidine-2,4-dione derivatives as novel protein tyrosine phosphatase 1B inhibitors.
    Wang MY; Jin YY; Wei HY; Zhang LS; Sun SX; Chen XB; Dong WL; Xu WR; Cheng XC; Wang RL
    Eur J Med Chem; 2015 Oct; 103():91-104. PubMed ID: 26342135
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Novel thiophene derivatives as PTP1B inhibitors with selectivity and cellular activity.
    Ye D; Zhang Y; Wang F; Zheng M; Zhang X; Luo X; Shen X; Jiang H; Liu H
    Bioorg Med Chem; 2010 Mar; 18(5):1773-82. PubMed ID: 20153651
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Design and synthesis of paracaseolide A analogues as selective protein tyrosine phosphatase 1B inhibitors.
    Yin JP; Tang CL; Gao LX; Ma WP; Li JY; Li Y; Li J; Nan FJ
    Org Biomol Chem; 2014 Jun; 12(21):3441-5. PubMed ID: 24752625
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Potent inhibition of protein tyrosine phosphatases by copper complexes with multi-benzimidazole derivatives.
    Li Y; Lu L; Zhu M; Wang Q; Yuan C; Xing S; Fu X; Mei Y
    Biometals; 2011 Dec; 24(6):993-1004. PubMed ID: 21618062
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Beta-C-glycosiduronic acids and beta-C-glycosyl compounds: new PTP1B inhibitors.
    Lin L; Shen Q; Chen GR; Xie J
    Bioorg Med Chem Lett; 2008 Dec; 18(24):6348-51. PubMed ID: 18993066
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mono- and disalicylic acid derivatives: PTP1B inhibitors as potential anti-obesity drugs.
    Shrestha S; Bhattarai BR; Lee KH; Cho H
    Bioorg Med Chem; 2007 Oct; 15(20):6535-48. PubMed ID: 17692525
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Pyrrolo[2,3-c]azepine derivatives: a new class of potent protein tyrosine phosphatase 1B inhibitors.
    Xie J; Tian J; Su L; Huang M; Zhu X; Ye F; Wan Y
    Bioorg Med Chem Lett; 2011 Jul; 21(14):4306-9. PubMed ID: 21696953
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Design, synthesis, and biological evaluation of 2-substituted ethenesulfonic acid ester derivatives as selective PTP1B inhibitors.
    Liu J; Deng X; Jin Y; Xu B; Liu W; Jiang F; Fu L
    Pharmazie; 2015 Jul; 70(7):446-51. PubMed ID: 26373204
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design, Synthesis and Biological Evaluation of Stilbene Derivatives as Novel Inhibitors of Protein Tyrosine Phosphatase 1B.
    He H; Ge Y; Dai H; Cui S; Ye F; Jin J; Shi Y
    Molecules; 2016 Dec; 21(12):. PubMed ID: 27999292
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B.
    Li XQ; Xu Q; Luo J; Wang LJ; Jiang B; Zhang RS; Shi DY
    Eur J Med Chem; 2017 Aug; 136():348-359. PubMed ID: 28511130
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Novel, potent, selective and cellular active ABC type PTP1B inhibitors containing (methanesulfonyl-phenyl-amino)-acetic acid methyl ester phosphotyrosine mimetic.
    Liu P; Du Y; Song L; Shen J; Li Q
    Bioorg Med Chem; 2015 Nov; 23(21):7079-88. PubMed ID: 26481657
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis of novel 3-aryl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene derivatives and their biological evaluation against protein tyrosine phosphatase 1B.
    Wang WL; Chen X; Gao LX; Sheng L; Li JY; Li J; Feng B
    Chem Biol Drug Des; 2015 Nov; 86(5):1161-7. PubMed ID: 25996453
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Design and synthesis of 2-substituted benzoxazoles as novel PTP1B inhibitors.
    Chandrasekharappa AP; Badiger SE; Dubey PK; Panigrahi SK; Manukonda SR
    Bioorg Med Chem Lett; 2013 May; 23(9):2579-84. PubMed ID: 23528300
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Design and synthesis of imidazolidine-2,4-dione derivatives as selective inhibitors by targeting protein tyrosine phosphatase-1B over T-cell protein tyrosine phosphatase.
    Ma Y; Sun SX; Cheng XC; Wang SQ; Dong WL; Wang RL; Xu WR
    Chem Biol Drug Des; 2013 Nov; 82(5):595-602. PubMed ID: 23848232
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Dinuclear copper complexes of organic claw: potent inhibition of protein tyrosine phosphatases.
    Ma L; Lu L; Zhu M; Wang Q; Gao F; Yuan C; Wu Y; Xing S; Fu X; Mei Y; Gao X
    J Inorg Biochem; 2011 Sep; 105(9):1138-47. PubMed ID: 21708098
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 22.