82 related articles for article (PubMed ID: 22648632)
1. Synthesis of conformationally constrained benzoylureas as BH3-mimetics.
Brady RM; Hatzis E; Connor T; Street IP; Baell JB; Lessene G
Org Biomol Chem; 2012 Jul; 10(27):5230-7. PubMed ID: 22648632
[TBL] [Abstract][Full Text] [Related]
2. Structure and function of benzoylurea-derived alpha-helix mimetics targeting the Bcl-x(L)/Bak binding interface.
Rodriguez JM; Ross NT; Katt WP; Dhar D; Lee GI; Hamilton AD
ChemMedChem; 2009 Apr; 4(4):649-56. PubMed ID: 19330783
[TBL] [Abstract][Full Text] [Related]
3. Terphenyl-Based Bak BH3 alpha-helical proteomimetics as low-molecular-weight antagonists of Bcl-xL.
Yin H; Lee GI; Sedey KA; Kutzki O; Park HS; Orner BP; Ernst JT; Wang HG; Sebti SM; Hamilton AD
J Am Chem Soc; 2005 Jul; 127(29):10191-6. PubMed ID: 16028929
[TBL] [Abstract][Full Text] [Related]
4. Benzoylureas as removable cis amide inducers: synthesis of cyclic amides via ring closing metathesis (RCM).
Brady RM; Khakham Y; Lessene G; Baell JB
Org Biomol Chem; 2011 Feb; 9(3):656-8. PubMed ID: 21088766
[TBL] [Abstract][Full Text] [Related]
5. Targeting anti-apoptotic Bcl2 proteins with scyllatoxin-based BH3 domain mimetics.
Harris MM; Coon Z; Alqaeisoom N; Swords B; Holub JM
Org Biomol Chem; 2016 Jan; 14(2):440-446. PubMed ID: 26563651
[TBL] [Abstract][Full Text] [Related]
6. Piercing the armor of hepatobiliary cancer: Bcl-2 homology domain 3 (BH3) mimetics and cell death.
Mott JL; Gores GJ
Hepatology; 2007 Sep; 46(3):906-11. PubMed ID: 17654739
[No Abstract] [Full Text] [Related]
7. Role of single disulfide linkages in the folding and activity of scyllatoxin-based BH3 domain mimetics.
Arachchige D; Margaret Harris M; Coon Z; Carlsen J; Holub JM
J Pept Sci; 2017 May; 23(5):367-373. PubMed ID: 28326661
[TBL] [Abstract][Full Text] [Related]
8. Structure-based design of potent, conformationally constrained Smac mimetics.
Sun H; Nikolovska-Coleska Z; Yang CY; Xu L; Liu M; Tomita Y; Pan H; Yoshioka Y; Krajewski K; Roller PP; Wang S
J Am Chem Soc; 2004 Dec; 126(51):16686-7. PubMed ID: 15612682
[TBL] [Abstract][Full Text] [Related]
9. Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site.
Sun H; Nikolovska-Coleska Z; Yang CY; Xu L; Tomita Y; Krajewski K; Roller PP; Wang S
J Med Chem; 2004 Aug; 47(17):4147-50. PubMed ID: 15293984
[TBL] [Abstract][Full Text] [Related]
10. Synthesis of pyridazine-based scaffolds as alpha-helix mimetics.
Volonterio A; Moisan L; Rebek J
Org Lett; 2007 Sep; 9(19):3733-6. PubMed ID: 17711290
[TBL] [Abstract][Full Text] [Related]
11. Terephthalamide derivatives as mimetics of helical peptides: disruption of the Bcl-x(L)/Bak interaction.
Yin H; Lee GI; Sedey KA; Rodriguez JM; Wang HG; Sebti SM; Hamilton AD
J Am Chem Soc; 2005 Apr; 127(15):5463-8. PubMed ID: 15826183
[TBL] [Abstract][Full Text] [Related]
12. Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands.
Kvansakul M; Yang H; Fairlie WD; Czabotar PE; Fischer SF; Perugini MA; Huang DC; Colman PM
Cell Death Differ; 2008 Oct; 15(10):1564-71. PubMed ID: 18551131
[TBL] [Abstract][Full Text] [Related]
13. Amphiphilic α-helix mimetics based on a benzoylurea scaffold.
Thompson S; Hamilton AD
Org Biomol Chem; 2012 Aug; 10(30):5780-2. PubMed ID: 22532001
[TBL] [Abstract][Full Text] [Related]
14. De-novo designed library of benzoylureas as inhibitors of BCL-XL: synthesis, structural and biochemical characterization.
Brady RM; Vom A; Roy MJ; Toovey N; Smith BJ; Moss RM; Hatzis E; Huang DC; Parisot JP; Yang H; Street IP; Colman PM; Czabotar PE; Baell JB; Lessene G
J Med Chem; 2014 Feb; 57(4):1323-43. PubMed ID: 24456288
[TBL] [Abstract][Full Text] [Related]
15. A highly efficient type I β-turn mimetic simulating an Asx-Pro-turn-like structure.
Pinsker A; Einsiedel J; Härterich S; Waibel R; Gmeiner P
Org Lett; 2011 Jul; 13(13):3502-5. PubMed ID: 21657240
[TBL] [Abstract][Full Text] [Related]
16. Beta-hairpin peptidomimetics: design, structures and biological activities.
Robinson JA
Acc Chem Res; 2008 Oct; 41(10):1278-88. PubMed ID: 18412373
[TBL] [Abstract][Full Text] [Related]
17. Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1.
Day CL; Smits C; Fan FC; Lee EF; Fairlie WD; Hinds MG
J Mol Biol; 2008 Jul; 380(5):958-71. PubMed ID: 18589438
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and solid state conformation of phenylalanine mimetics constrained in a proline-like conformation.
Gardiner J; Abell AD
Org Biomol Chem; 2004 Aug; 2(16):2365-70. PubMed ID: 15305220
[TBL] [Abstract][Full Text] [Related]
19. Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics.
Oishi S; Karki RG; Kang SU; Wang X; Worthy KM; Bindu LK; Nicklaus MC; Fisher RJ; Burke TR
J Med Chem; 2005 Feb; 48(3):764-72. PubMed ID: 15689160
[TBL] [Abstract][Full Text] [Related]
20. Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitors.
Yap JL; Cao X; Vanommeslaeghe K; Jung KY; Peddaboina C; Wilder PT; Nan A; MacKerell AD; Smythe WR; Fletcher S
Org Biomol Chem; 2012 Apr; 10(15):2928-33. PubMed ID: 22395339
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
