BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 22651090)

  • 1. Redox properties of the disulfide bond of human Cu,Zn superoxide dismutase and the effects of human glutaredoxin 1.
    Bouldin SD; Darch MA; Hart PJ; Outten CE
    Biochem J; 2012 Aug; 446(1):59-67. PubMed ID: 22651090
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cellular Redox Systems Impact the Aggregation of Cu,Zn Superoxide Dismutase Linked to Familial Amyotrophic Lateral Sclerosis.
    Álvarez-Zaldiernas C; Lu J; Zheng Y; Yang H; Blasi J; Solsona C; Holmgren A
    J Biol Chem; 2016 Aug; 291(33):17197-208. PubMed ID: 27261461
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The involvement of GSH in the activation of human Sod1 linked to FALS in chronologically aged yeast cells.
    Brasil AA; Belati A; Mannarino SC; Panek AD; Eleutherio EC; Pereira MD
    FEMS Yeast Res; 2013 Aug; 13(5):433-40. PubMed ID: 23496883
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Disulfide Bond, but Not Zinc or Dimerization, Controls Initiation and Seeded Growth in Amyotrophic Lateral Sclerosis-linked Cu,Zn Superoxide Dismutase (SOD1) Fibrillation.
    Chattopadhyay M; Nwadibia E; Strong CD; Gralla EB; Valentine JS; Whitelegge JP
    J Biol Chem; 2015 Dec; 290(51):30624-36. PubMed ID: 26511321
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Altered thiol chemistry in human amyotrophic lateral sclerosis-linked mutants of superoxide dismutase 1.
    Solsona C; Kahn TB; Badilla CL; Álvarez-Zaldiernas C; Blasi J; Fernandez JM; Alegre-Cebollada J
    J Biol Chem; 2014 Sep; 289(39):26722-26732. PubMed ID: 25096579
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The effects of glutaredoxin and copper activation pathways on the disulfide and stability of Cu,Zn superoxide dismutase.
    Carroll MC; Outten CE; Proescher JB; Rosenfeld L; Watson WH; Whitson LJ; Hart PJ; Jensen LT; Cizewski Culotta V
    J Biol Chem; 2006 Sep; 281(39):28648-56. PubMed ID: 16880213
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Disulfide-reduced ALS variants of Cu, Zn superoxide dismutase exhibit increased populations of unfolded species.
    Kayatekin C; Zitzewitz JA; Matthews CR
    J Mol Biol; 2010 Apr; 398(2):320-31. PubMed ID: 20184893
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Amyotrophic lateral sclerosis mutations have the greatest destabilizing effect on the apo- and reduced form of SOD1, leading to unfolding and oxidative aggregation.
    Furukawa Y; O'Halloran TV
    J Biol Chem; 2005 Apr; 280(17):17266-74. PubMed ID: 15691826
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
    Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modulation of mutant superoxide dismutase 1 aggregation by co-expression of wild-type enzyme.
    Prudencio M; Durazo A; Whitelegge JP; Borchelt DR
    J Neurochem; 2009 Feb; 108(4):1009-18. PubMed ID: 19077113
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Folding of Cu, Zn superoxide dismutase and familial amyotrophic lateral sclerosis.
    Khare SD; Ding F; Dokholyan NV
    J Mol Biol; 2003 Nov; 334(3):515-25. PubMed ID: 14623191
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase.
    Sea K; Sohn SH; Durazo A; Sheng Y; Shaw BF; Cao X; Taylor AB; Whitson LJ; Holloway SP; Hart PJ; Cabelli DE; Gralla EB; Valentine JS
    J Biol Chem; 2015 Jan; 290(4):2405-18. PubMed ID: 25433341
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Loss of metal ions, disulfide reduction and mutations related to familial ALS promote formation of amyloid-like aggregates from superoxide dismutase.
    Oztug Durer ZA; Cohlberg JA; Dinh P; Padua S; Ehrenclou K; Downes S; Tan JK; Nakano Y; Bowman CJ; Hoskins JL; Kwon C; Mason AZ; Rodriguez JA; Doucette PA; Shaw BF; Valentine JS
    PLoS One; 2009; 4(3):e5004. PubMed ID: 19325915
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human superoxide dismutase 1 (hSOD1) maturation through interaction with human copper chaperone for SOD1 (hCCS).
    Banci L; Bertini I; Cantini F; Kozyreva T; Massagni C; Palumaa P; Rubino JT; Zovo K
    Proc Natl Acad Sci U S A; 2012 Aug; 109(34):13555-60. PubMed ID: 22869735
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The unusually stable quaternary structure of human Cu,Zn-superoxide dismutase 1 is controlled by both metal occupancy and disulfide status.
    Arnesano F; Banci L; Bertini I; Martinelli M; Furukawa Y; O'Halloran TV
    J Biol Chem; 2004 Nov; 279(46):47998-8003. PubMed ID: 15326189
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice.
    Furukawa Y; Fu R; Deng HX; Siddique T; O'Halloran TV
    Proc Natl Acad Sci U S A; 2006 May; 103(18):7148-53. PubMed ID: 16636274
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glutaredoxin 2 prevents aggregation of mutant SOD1 in mitochondria and abolishes its toxicity.
    Ferri A; Fiorenzo P; Nencini M; Cozzolino M; Pesaresi MG; Valle C; Sepe S; Moreno S; Carrì MT
    Hum Mol Genet; 2010 Nov; 19(22):4529-42. PubMed ID: 20829229
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conformational Disorder of the Most Immature Cu, Zn-Superoxide Dismutase Leading to Amyotrophic Lateral Sclerosis.
    Furukawa Y; Anzai I; Akiyama S; Imai M; Cruz FJ; Saio T; Nagasawa K; Nomura T; Ishimori K
    J Biol Chem; 2016 Feb; 291(8):4144-55. PubMed ID: 26694608
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutant superoxide dismutase aggregates from human spinal cord transmit amyotrophic lateral sclerosis.
    Ekhtiari Bidhendi E; Bergh J; Zetterström P; Forsberg K; Pakkenberg B; Andersen PM; Marklund SL; Brännström T
    Acta Neuropathol; 2018 Dec; 136(6):939-953. PubMed ID: 30284034
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanical probes of SOD1 predict systematic trends in metal and dimer affinity of ALS-associated mutants.
    Das A; Plotkin SS
    J Mol Biol; 2013 Mar; 425(5):850-74. PubMed ID: 23291526
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.