BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 22651685)

  • 21. Optimization of the assembly efficiency for lidamycin chromophore bound to its apoprotein: a case study using orthogonal array.
    Zhong GS; Guo XF; Zhang SH; Zhen YS
    Biomed Environ Sci; 2011 Dec; 24(6):602-7. PubMed ID: 22365395
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Genetically engineered endostatin-lidamycin fusion proteins effectively inhibit tumor growth and metastasis.
    Jiang WG; Lu XA; Shang BY; Fu Y; Zhang SH; Zhou D; Li L; Li Y; Luo Y; Zhen YS
    BMC Cancer; 2013 Oct; 13():479. PubMed ID: 24128285
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A Macropinocytosis-Intensifying Albumin Domain-Based scFv Antibody and Its Conjugate Directed against K-Ras Mutant Pancreatic Cancer.
    Wang X; Sheng W; Wang Y; Li L; Li Y; Zhang S; Liu X; Chen S; Zhen Y
    Mol Pharm; 2018 Jun; 15(6):2403-2412. PubMed ID: 29757658
    [TBL] [Abstract][Full Text] [Related]  

  • 24. MMP-2/9-oriented combinations enhance antitumor efficacy of EGFR/HER2-targeting fusion proteins and gemcitabine.
    Qin Y; Liu XJ; Li L; Liu XJ; Li Y; Gao RJ; Shao RG; Zhen YS
    Oncol Rep; 2014 Jul; 32(1):121-30. PubMed ID: 24807584
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A novel enediyne-integrated antibody-drug conjugate shows promising antitumor efficacy against CD30
    Wang R; Li L; Zhang S; Li Y; Wang X; Miao Q; Zhen Y
    Mol Oncol; 2018 Mar; 12(3):339-355. PubMed ID: 29316337
    [TBL] [Abstract][Full Text] [Related]  

  • 26. An enediyne-energized single-domain antibody-containing fusion protein shows potent antitumor activity.
    Miao QF; Liu XY; Shang BY; Ouyang ZG; Zhen YS
    Anticancer Drugs; 2007 Feb; 18(2):127-37. PubMed ID: 17159599
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A recombinant scFv antibody-based fusion protein that targets EGFR associated with IMPDH2 downregulation and its drug conjugate show therapeutic efficacy against esophageal cancer.
    He S; Zhao C; Tao H; Sheng W; Gao R; Liu X; Zhen Y
    Drug Deliv; 2022 Dec; 29(1):1243-1256. PubMed ID: 35416106
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Enediyne-activated, EGFR-targeted human β-defensin 1 has therapeutic efficacy against non-small cell lung carcinoma.
    Liu WJ; Zhu KL; Xu J; Wang JL; Zhu H
    Lab Invest; 2018 Dec; 98(12):1538-1548. PubMed ID: 30206309
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Antitumor efficacy of lidamycin on hepatoma and active moiety of its molecule.
    Huang YH; Shang BY; Zhen YS
    World J Gastroenterol; 2005 Jul; 11(26):3980-4. PubMed ID: 15996019
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Small antibody fusion proteins with complementarity-determining regions and lidamycin for tumor targeting therapy.
    Zhong GS; Wu MN; Guo XF; Xu ZS; Zhang SH; Zhen YS
    Oncol Lett; 2013 Apr; 5(4):1183-1188. PubMed ID: 23599760
    [TBL] [Abstract][Full Text] [Related]  

  • 31. An arginine-rich cell penetrating peptide contained anti-gelatinase scFv-LDM fusion protein shows potent antitumor efficacy in pancreatic cancer.
    Zhong G; Xu Z; Yang R; Zhang S; Li L; Wu M; Liu H; Zhen Y
    J Cancer; 2018; 9(4):674-682. PubMed ID: 29556325
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Construction of a genetically engineered chimeric apoprotein consisting of sequences derived from lidamycin and neocarzinostatin.
    Jiang W; Shang B; Li L; Zhang S; Zhen Y
    Anticancer Drugs; 2016 Jan; 27(1):24-8. PubMed ID: 26457548
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Recombinant EGFR/MMP-2 bi-targeted fusion protein markedly binding to non-small-cell lung carcinoma and exerting potent therapeutic efficacy.
    Xu J; Du Y; Liu XJ; Zhu BY; Zhang SH; Li L; Li Y; Wang XF; Shan CK; Wang RQ; Zhen YS
    Pharmacol Res; 2017 Dec; 126():66-76. PubMed ID: 28392461
    [TBL] [Abstract][Full Text] [Related]  

  • 34. [Lidamycin inhibits the proliferation of HERG K+ channel highly expressing cancer cells and shows synergy with anticancer drugs].
    Shang BY; Shang Y; Zhen YS; Chen SZ
    Yao Xue Xue Bao; 2011 Nov; 46(11):1321-5. PubMed ID: 22260022
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers.
    Zhou DD; Zhai XT; Zhang LW; Xie ZH; Wang Y; Zhen YS; Gao RJ; Miao QF
    NPJ Precis Oncol; 2024 Apr; 8(1):94. PubMed ID: 38654141
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The Recombinant and Reconstituted Novel Albumin-Lidamycin Conjugate Shows Lasting Tumor Imaging and Intensively Enhanced Therapeutic Efficacy.
    Li L; Hu L; Zhao CY; Zhang SH; Wang R; Li Y; Shao RG; Zhen YS
    Bioconjug Chem; 2018 Sep; 29(9):3104-3112. PubMed ID: 30105903
    [TBL] [Abstract][Full Text] [Related]  

  • 37. EGFR-targeting, β-defensin-tailored fusion protein exhibits high therapeutic efficacy against EGFR-expressed human carcinoma via mitochondria-mediated apoptosis.
    Liu WJ; Liu XJ; Xu J; Li L; Li Y; Zhang SH; Wang JL; Miao QF; Zhen YS
    Acta Pharmacol Sin; 2018 Nov; 39(11):1777-1786. PubMed ID: 30013033
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Binding capability of the enediyne-associated apoprotein to human tumors and constitution of a ligand oligopeptide-integrated protein.
    Cai L; Chen H; Miao Q; Wu S; Shang Y; Zhen Y
    J Biotechnol; 2009 Oct; 144(2):142-50. PubMed ID: 19737585
    [TBL] [Abstract][Full Text] [Related]  

  • 39. An engineered TIMP2-based and enediyne-integrated fusion protein for targeting MMP-14 shows potent antitumor efficacy.
    Xu J; Liu XJ; Li L; Zhang SH; Li Y; Gao RJ; Zhen YS
    Oncotarget; 2015 Sep; 6(28):26322-34. PubMed ID: 26314845
    [TBL] [Abstract][Full Text] [Related]  

  • 40. [Binding capability of lidamycin apoprotein to human breast cancer detected by tissue microarrays].
    Cai L; Gao RJ; Guo XZ; Li Y; Zhen YS
    Yao Xue Xue Bao; 2010 May; 45(5):582-8. PubMed ID: 20931759
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.