258 related articles for article (PubMed ID: 22653441)
1. Group I and II mammalian PAKs have different modes of activation by Cdc42.
Baskaran Y; Ng YW; Selamat W; Ling FT; Manser E
EMBO Rep; 2012 Jun; 13(7):653-9. PubMed ID: 22653441
[TBL] [Abstract][Full Text] [Related]
2. CDC42 binds PAK4 via an extended GTPase-effector interface.
Ha BH; Boggon TJ
Proc Natl Acad Sci U S A; 2018 Jan; 115(3):531-536. PubMed ID: 29295922
[TBL] [Abstract][Full Text] [Related]
3. NMR binding and crystal structure reveal that intrinsically-unstructured regulatory domain auto-inhibits PAK4 by a mechanism different from that of PAK1.
Wang W; Lim L; Baskaran Y; Manser E; Song J
Biochem Biophys Res Commun; 2013 Aug; 438(1):169-74. PubMed ID: 23876315
[TBL] [Abstract][Full Text] [Related]
4. Solution structures and biophysical analysis of full-length group A PAKs reveal they are monomeric and auto-inhibited in
Sorrell FJ; Kilian LM; Elkins JM
Biochem J; 2019 Apr; 476(7):1037-1051. PubMed ID: 30858169
[TBL] [Abstract][Full Text] [Related]
5. PAK5 is auto-activated by a central domain that promotes kinase oligomerization.
Tabanifar B; Zhao Z; Manser E
Biochem J; 2016 Jun; 473(12):1777-89. PubMed ID: 27095851
[TBL] [Abstract][Full Text] [Related]
6. The subcellular localization of type I p21-activated kinases is controlled by the disordered variable region and polybasic sequences.
Sun X; Su VL; Calderwood DA
J Biol Chem; 2019 Sep; 294(39):14319-14332. PubMed ID: 31391252
[TBL] [Abstract][Full Text] [Related]
7. Identification of an autoinhibitory domain of p21-activated protein kinase 5.
Ching YP; Leong VY; Wong CM; Kung HF
J Biol Chem; 2003 Sep; 278(36):33621-4. PubMed ID: 12860998
[TBL] [Abstract][Full Text] [Related]
8. PAK is regulated by PI3K, PIX, CDC42, and PP2Calpha and mediates focal adhesion turnover in the hyperosmotic stress-induced p38 pathway.
Chan PM; Lim L; Manser E
J Biol Chem; 2008 Sep; 283(36):24949-61. PubMed ID: 18586681
[TBL] [Abstract][Full Text] [Related]
9. Evidence for a novel mechanism of the PAK1 interaction with the Rho-GTPases Cdc42 and Rac.
Shin YJ; Kim EH; Roy A; Kim JH
PLoS One; 2013; 8(8):e71495. PubMed ID: 23936510
[TBL] [Abstract][Full Text] [Related]
10. Signaling, Regulation, and Specificity of the Type II p21-activated Kinases.
Ha BH; Morse EM; Turk BE; Boggon TJ
J Biol Chem; 2015 May; 290(21):12975-83. PubMed ID: 25855792
[TBL] [Abstract][Full Text] [Related]
11. P21 activated kinases: structure, regulation, and functions.
Rane CK; Minden A
Small GTPases; 2014; 5():. PubMed ID: 24658305
[TBL] [Abstract][Full Text] [Related]
12. Specificity profiling of Pak kinases allows identification of novel phosphorylation sites.
Rennefahrt UE; Deacon SW; Parker SA; Devarajan K; Beeser A; Chernoff J; Knapp S; Turk BE; Peterson JR
J Biol Chem; 2007 May; 282(21):15667-78. PubMed ID: 17392278
[TBL] [Abstract][Full Text] [Related]
13. Cdc42 regulates apical junction formation in human bronchial epithelial cells through PAK4 and Par6B.
Wallace SW; Durgan J; Jin D; Hall A
Mol Biol Cell; 2010 Sep; 21(17):2996-3006. PubMed ID: 20631255
[TBL] [Abstract][Full Text] [Related]
14. Regulation of the interaction of Pak2 with Cdc42 via autophosphorylation of serine 141.
Jung JH; Traugh JA
J Biol Chem; 2005 Dec; 280(48):40025-31. PubMed ID: 16204230
[TBL] [Abstract][Full Text] [Related]
15. Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate.
Ha BH; Davis MJ; Chen C; Lou HJ; Gao J; Zhang R; Krauthammer M; Halaban R; Schlessinger J; Turk BE; Boggon TJ
Proc Natl Acad Sci U S A; 2012 Oct; 109(40):16107-12. PubMed ID: 22988085
[TBL] [Abstract][Full Text] [Related]
16. Phosphorylation-dependent activity-based conformational changes in P21-activated kinase family members and screening of novel ATP competitive inhibitors.
Gul M; Fakhar M; Najumuddin ; Rashid S
PLoS One; 2019; 14(11):e0225132. PubMed ID: 31738805
[TBL] [Abstract][Full Text] [Related]
17. Involvement of Rac/Cdc42/PAK pathway in cytoskeletal rearrangements.
Szczepanowska J
Acta Biochim Pol; 2009; 56(2):225-34. PubMed ID: 19513348
[TBL] [Abstract][Full Text] [Related]
18. The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity.
Selamat W; Tay PL; Baskaran Y; Manser E
PLoS One; 2015; 10(6):e0129634. PubMed ID: 26068882
[TBL] [Abstract][Full Text] [Related]
19. Synapsin I is phosphorylated at Ser603 by p21-activated kinases (PAKs) in vitro and in PC12 cells stimulated with bradykinin.
Sakurada K; Kato H; Nagumo H; Hiraoka H; Furuya K; Ikuhara T; Yamakita Y; Fukunaga K; Miyamoto E; Matsumura F; Matsuo YI; Naito Y; Sasaki Y
J Biol Chem; 2002 Nov; 277(47):45473-9. PubMed ID: 12237306
[TBL] [Abstract][Full Text] [Related]
20. Dissecting activation of the PAK1 kinase at protrusions in living cells.
Parrini MC; Camonis J; Matsuda M; de Gunzburg J
J Biol Chem; 2009 Sep; 284(36):24133-43. PubMed ID: 19574218
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
