BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 22659875)

  • 1. AMP-activated protein kinase undergoes nucleotide-dependent conformational changes.
    Chen L; Wang J; Zhang YY; Yan SF; Neumann D; Schlattner U; Wang ZX; Wu JW
    Nat Struct Mol Biol; 2012 Jun; 19(7):716-8. PubMed ID: 22659875
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular Mechanism of Nucleotide-Dependent Allosteric Regulation in AMP-Activated Protein Kinase.
    Ahalawat N; Murarka RK
    J Phys Chem B; 2017 Apr; 121(14):2919-2930. PubMed ID: 28345916
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensing.
    Gu X; Yan Y; Novick SJ; Kovach A; Goswami D; Ke J; Tan MHE; Wang L; Li X; de Waal PW; Webb MR; Griffin PR; Xu HE; Melcher K
    J Biol Chem; 2017 Jul; 292(30):12653-12666. PubMed ID: 28615457
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure and Physiological Regulation of AMPK.
    Yan Y; Zhou XE; Xu HE; Melcher K
    Int J Mol Sci; 2018 Nov; 19(11):. PubMed ID: 30423971
    [TBL] [Abstract][Full Text] [Related]  

  • 5. AMPK functions as an adenylate charge-regulated protein kinase.
    Oakhill JS; Scott JW; Kemp BE
    Trends Endocrinol Metab; 2012 Mar; 23(3):125-32. PubMed ID: 22284532
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseases.
    Rana S; Blowers EC; Natarajan A
    J Med Chem; 2015 Jan; 58(1):2-29. PubMed ID: 25122135
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural and biochemical insights into the allosteric activation mechanism of AMP-activated protein kinase.
    Li J; Li S; Wang F; Xin F
    Chem Biol Drug Des; 2017 May; 89(5):663-669. PubMed ID: 27809416
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators.
    Rajamohan F; Reyes AR; Frisbie RK; Hoth LR; Sahasrabudhe P; Magyar R; Landro JA; Withka JM; Caspers NL; Calabrese MF; Ward J; Kurumbail RG
    Biochem J; 2016 Mar; 473(5):581-92. PubMed ID: 26635351
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural basis of AMPK regulation by adenine nucleotides and glycogen.
    Li X; Wang L; Zhou XE; Ke J; de Waal PW; Gu X; Tan MH; Wang D; Wu D; Xu HE; Melcher K
    Cell Res; 2015 Jan; 25(1):50-66. PubMed ID: 25412657
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of AMP-activated protein kinase revealed by hydrogen/deuterium exchange mass spectrometry.
    Landgraf RR; Goswami D; Rajamohan F; Harris MS; Calabrese MF; Hoth LR; Magyar R; Pascal BD; Chalmers MJ; Busby SA; Kurumbail RG; Griffin PR
    Structure; 2013 Nov; 21(11):1942-53. PubMed ID: 24076403
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AMPK: Sensing Glucose as well as Cellular Energy Status.
    Lin SC; Hardie DG
    Cell Metab; 2018 Feb; 27(2):299-313. PubMed ID: 29153408
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states.
    Yan Y; Zhou XE; Novick SJ; Shaw SJ; Li Y; Brunzelle JS; Hitoshi Y; Griffin PR; Xu HE; Melcher K
    J Biol Chem; 2019 Jan; 294(3):953-967. PubMed ID: 30478170
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intact Cell Assays to Monitor AMPK and Determine the Contribution of the AMP-Binding or ADaM Sites to Activation.
    Hawley SA; Fyffe FA; Russell FM; Gowans GJ; Grahame Hardie D
    Methods Mol Biol; 2018; 1732():239-253. PubMed ID: 29480480
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Allosteric Modulation of AMPK Enzymatic Activity: In Vitro Characterization.
    Ward J; Reyes AR; Kurumbail RG
    Methods Enzymol; 2017; 587():481-509. PubMed ID: 28253974
    [TBL] [Abstract][Full Text] [Related]  

  • 15. AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer.
    Hardie DG
    Biochem Soc Trans; 2011 Jan; 39(1):1-13. PubMed ID: 21265739
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK).
    Gu X; Bridges MD; Yan Y; de Waal PW; Zhou XE; Suino-Powell KM; Xu HE; Hubbell WL; Melcher K
    J Biol Chem; 2018 Nov; 293(44):16994-17007. PubMed ID: 30206123
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural insights into the architecture and allostery of full-length AMP-activated protein kinase.
    Zhu L; Chen L; Zhou XM; Zhang YY; Zhang YJ; Zhao J; Ji SR; Wu JW; Wu Y
    Structure; 2011 Apr; 19(4):515-22. PubMed ID: 21481774
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms.
    Ross FA; Jensen TE; Hardie DG
    Biochem J; 2016 Jan; 473(2):189-99. PubMed ID: 26542978
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthetic energy sensor AMPfret deciphers adenylate-dependent AMPK activation mechanism.
    Pelosse M; Cottet-Rousselle C; Bidan CM; Dupont A; Gupta K; Berger I; Schlattner U
    Nat Commun; 2019 Mar; 10(1):1038. PubMed ID: 30833561
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural insight into the autoinhibition mechanism of AMP-activated protein kinase.
    Chen L; Jiao ZH; Zheng LS; Zhang YY; Xie ST; Wang ZX; Wu JW
    Nature; 2009 Jun; 459(7250):1146-9. PubMed ID: 19474788
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.