BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 22665058)

  • 1. Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation.
    Radulescu S; Ridgway RA; Cordero J; Athineos D; Salgueiro P; Poulsom R; Neumann J; Jung A; Patel S; Woodgett J; Barker N; Pritchard DM; Oien K; Sansom OJ
    Oncogene; 2013 Apr; 32(16):2048-57. PubMed ID: 22665058
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Region-specific Wnt signaling responses promote gastric polyp formation in patients with familial adenomatous polyposis.
    McGowan KP; Delgado E; Keeley TM; Hibdon ES; Turgeon DK; Stoffel EM; Samuelson LC
    JCI Insight; 2023 Nov; 8(24):. PubMed ID: 37943618
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oncogenic KRAS is not necessary for Wnt signalling activation in APC-associated FAP adenomas.
    Obrador-Hevia A; Chin SF; González S; Rees J; Vilardell F; Greenson JK; Cordero D; Moreno V; Caldas C; Capellá G
    J Pathol; 2010 May; 221(1):57-67. PubMed ID: 20196079
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alteration in the Wnt/β-catenin signaling pathway in gastric neoplasias of fundic gland (chief cell predominant) type.
    Hidaka Y; Mitomi H; Saito T; Takahashi M; Lee SY; Matsumoto K; Yao T; Watanabe S
    Hum Pathol; 2013 Nov; 44(11):2438-48. PubMed ID: 24011952
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Severe polyposis in Apc(1322T) mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5.
    Lewis A; Segditsas S; Deheragoda M; Pollard P; Jeffery R; Nye E; Lockstone H; Davis H; Clark S; Stamp G; Poulsom R; Wright N; Tomlinson I
    Gut; 2010 Dec; 59(12):1680-6. PubMed ID: 20926645
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activated macrophages promote Wnt signalling through tumour necrosis factor-alpha in gastric tumour cells.
    Oguma K; Oshima H; Aoki M; Uchio R; Naka K; Nakamura S; Hirao A; Saya H; Taketo MM; Oshima M
    EMBO J; 2008 Jun; 27(12):1671-81. PubMed ID: 18511911
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis.
    Gaspar C; Franken P; Molenaar L; Breukel C; van der Valk M; Smits R; Fodde R
    PLoS Genet; 2009 Jul; 5(7):e1000547. PubMed ID: 19578404
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of gastric tumors in Apc(Min/+) mice by the activation of the beta-catenin/Tcf signaling pathway.
    Tomita H; Yamada Y; Oyama T; Hata K; Hirose Y; Hara A; Kunisada T; Sugiyama Y; Adachi Y; Linhart H; Mori H
    Cancer Res; 2007 May; 67(9):4079-87. PubMed ID: 17483318
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The effect of a germline mutation in the APC gene on β-catenin in human embryonic stem cells.
    Yedid N; Kalma Y; Malcov M; Amit A; Kariv R; Caspi M; Rosin-Arbesfeld R; Ben-Yosef D
    BMC Cancer; 2016 Dec; 16(1):952. PubMed ID: 28010732
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypermethylation of adenomatous polyposis coli gene promoter is associated with novel Wnt signaling pathway in gastric adenomas.
    Wang ZK; Liu J; Liu C; Wang FY; Chen CY; Zhang XH
    J Gastroenterol Hepatol; 2012 Oct; 27(10):1629-34. PubMed ID: 22741528
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation.
    Yang K; Popova NV; Yang WC; Lozonschi I; Tadesse S; Kent S; Bancroft L; Matise I; Cormier RT; Scherer SJ; Edelmann W; Lipkin M; Augenlicht L; Velcich A
    Cancer Res; 2008 Sep; 68(18):7313-22. PubMed ID: 18794118
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparison of dysplastic fundic gland polyps in patients with and without familial adenomatous polyposis.
    Straub SF; Drage MG; Gonzalez RS
    Histopathology; 2018 Jun; 72(7):1172-1179. PubMed ID: 29436014
    [TBL] [Abstract][Full Text] [Related]  

  • 13. different Roles for the axin interactions with the SAMP versus the second twenty amino acid repeat of adenomatous polyposis coli.
    Schneikert J; Ruppert JG; Behrens J; Wenzel EM
    PLoS One; 2014; 9(4):e94413. PubMed ID: 24722208
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MicroRNA-1229 overexpression promotes cell proliferation and tumorigenicity and activates Wnt/β-catenin signaling in breast cancer.
    Tan Z; Zheng H; Liu X; Zhang W; Zhu J; Wu G; Cao L; Song J; Wu S; Song L; Li J
    Oncotarget; 2016 Apr; 7(17):24076-87. PubMed ID: 26992223
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reduced level of smoothened suppresses intestinal tumorigenesis by down-regulation of Wnt signaling.
    Arimura S; Matsunaga A; Kitamura T; Aoki K; Aoki M; Taketo MM
    Gastroenterology; 2009 Aug; 137(2):629-38. PubMed ID: 19427313
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling.
    Zhang J; Cao H; Zhang B; Cao H; Xu X; Ruan H; Yi T; Tan L; Qu R; Song G; Wang B; Hu T
    J Cell Mol Med; 2013 Nov; 17(11):1484-93. PubMed ID: 24015932
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nuclear beta-catenin expression and Wnt signalling: in defence of the dogma.
    Fodde R; Tomlinson I
    J Pathol; 2010 Jul; 221(3):239-41. PubMed ID: 20527017
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Impact of Helicobacter pylori infection and mucosal atrophy on gastric lesions in patients with familial adenomatous polyposis.
    Nakamura S; Matsumoto T; Kobori Y; Iida M
    Gut; 2002 Oct; 51(4):485-9. PubMed ID: 12235068
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis.
    Ghaleb AM; McConnell BB; Nandan MO; Katz JP; Kaestner KH; Yang VW
    Cancer Res; 2007 Aug; 67(15):7147-54. PubMed ID: 17671182
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cross-species comparison of human and mouse intestinal polyps reveals conserved mechanisms in adenomatous polyposis coli (APC)-driven tumorigenesis.
    Gaspar C; Cardoso J; Franken P; Molenaar L; Morreau H; Möslein G; Sampson J; Boer JM; de Menezes RX; Fodde R
    Am J Pathol; 2008 May; 172(5):1363-80. PubMed ID: 18403596
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.