267 related articles for article (PubMed ID: 22665065)
1. Opposing functions of Fbxw7 in keratinocyte growth, differentiation and skin tumorigenesis mediated through negative regulation of c-Myc and Notch.
Ishikawa Y; Hosogane M; Okuyama R; Aoyama S; Onoyama I; Nakayama KI; Nakayama K
Oncogene; 2013 Apr; 32(15):1921-32. PubMed ID: 22665065
[TBL] [Abstract][Full Text] [Related]
2. Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation.
Fujii Y; Yada M; Nishiyama M; Kamura T; Takahashi H; Tsunematsu R; Susaki E; Nakagawa T; Matsumoto A; Nakayama KI
Cancer Sci; 2006 Aug; 97(8):729-36. PubMed ID: 16863506
[TBL] [Abstract][Full Text] [Related]
3. Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis.
Onoyama I; Tsunematsu R; Matsumoto A; Kimura T; de Alborán IM; Nakayama K; Nakayama KI
J Exp Med; 2007 Nov; 204(12):2875-88. PubMed ID: 17984302
[TBL] [Abstract][Full Text] [Related]
4. Recombinant human adenovirus-p53 injection induced apoptosis in hepatocellular carcinoma cell lines mediated by p53-Fbxw7 pathway, which controls c-Myc and cyclin E.
Tu K; Zheng X; Zhou Z; Li C; Zhang J; Gao J; Yao Y; Liu Q
PLoS One; 2013; 8(7):e68574. PubMed ID: 23840897
[TBL] [Abstract][Full Text] [Related]
5. The Fbxw7/hCdc4 tumor suppressor in human cancer.
Tan Y; Sangfelt O; Spruck C
Cancer Lett; 2008 Nov; 271(1):1-12. PubMed ID: 18541364
[TBL] [Abstract][Full Text] [Related]
6. Fbxw7 controls angiogenesis by regulating endothelial Notch activity.
Izumi N; Helker C; Ehling M; Behrens A; Herzog W; Adams RH
PLoS One; 2012; 7(7):e41116. PubMed ID: 22848434
[TBL] [Abstract][Full Text] [Related]
7. Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver.
Onoyama I; Suzuki A; Matsumoto A; Tomita K; Katagiri H; Oike Y; Nakayama K; Nakayama KI
J Clin Invest; 2011 Jan; 121(1):342-54. PubMed ID: 21123947
[TBL] [Abstract][Full Text] [Related]
8. Increased efficiency in the generation of induced pluripotent stem cells by Fbxw7 ablation.
Okita Y; Matsumoto A; Yumimoto K; Isoshita R; Nakayama KI
Genes Cells; 2012 Sep; 17(9):768-77. PubMed ID: 22897623
[TBL] [Abstract][Full Text] [Related]
9. Tumor suppressor activities of the Fbw7 E3 ubiquitin ligase receptor.
Fuchs SY
Cancer Biol Ther; 2005 May; 4(5):506-8. PubMed ID: 15908780
[TBL] [Abstract][Full Text] [Related]
10. Complex regulation of cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts.
Masuda K; Ishikawa Y; Onoyama I; Unno M; de Alborán IM; Nakayama KI; Nakayama K
Oncogene; 2010 Mar; 29(12):1798-809. PubMed ID: 20023701
[TBL] [Abstract][Full Text] [Related]
11. FBXW7/hCDC4 is a general tumor suppressor in human cancer.
Akhoondi S; Sun D; von der Lehr N; Apostolidou S; Klotz K; Maljukova A; Cepeda D; Fiegl H; Dafou D; Marth C; Mueller-Holzner E; Corcoran M; Dagnell M; Nejad SZ; Nayer BN; Zali MR; Hansson J; Egyhazi S; Petersson F; Sangfelt P; Nordgren H; Grander D; Reed SI; Widschwendter M; Sangfelt O; Spruck C
Cancer Res; 2007 Oct; 67(19):9006-12. PubMed ID: 17909001
[TBL] [Abstract][Full Text] [Related]
12. MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7.
Xu Y; Sengupta T; Kukreja L; Minella AC
J Biol Chem; 2010 Nov; 285(45):34439-46. PubMed ID: 20826802
[TBL] [Abstract][Full Text] [Related]
13. Fbxw7-dependent degradation of Notch is required for control of "stemness" and neuronal-glial differentiation in neural stem cells.
Matsumoto A; Onoyama I; Sunabori T; Kageyama R; Okano H; Nakayama KI
J Biol Chem; 2011 Apr; 286(15):13754-64. PubMed ID: 21349854
[TBL] [Abstract][Full Text] [Related]
14. MYC is a critical target of FBXW7.
Sato M; Rodriguez-Barrueco R; Yu J; Do C; Silva JM; Gautier J
Oncotarget; 2015 Feb; 6(5):3292-305. PubMed ID: 25669969
[TBL] [Abstract][Full Text] [Related]
15. F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.
Sancho R; Jandke A; Davis H; Diefenbacher ME; Tomlinson I; Behrens A
Gastroenterology; 2010 Sep; 139(3):929-41. PubMed ID: 20638938
[TBL] [Abstract][Full Text] [Related]
16. Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase.
Isobe T; Hattori T; Kitagawa K; Uchida C; Kotake Y; Kosugi I; Oda T; Kitagawa M
J Biol Chem; 2009 Oct; 284(41):27766-27779. PubMed ID: 19679664
[TBL] [Abstract][Full Text] [Related]
17. A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
Welcker M; Orian A; Grim JE; Eisenman RN; Clurman BE
Curr Biol; 2004 Oct; 14(20):1852-7. PubMed ID: 15498494
[TBL] [Abstract][Full Text] [Related]
18. FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.
Babaei-Jadidi R; Li N; Saadeddin A; Spencer-Dene B; Jandke A; Muhammad B; Ibrahim EE; Muraleedharan R; Abuzinadah M; Davis H; Lewis A; Watson S; Behrens A; Tomlinson I; Nateri AS
J Exp Med; 2011 Feb; 208(2):295-312. PubMed ID: 21282377
[TBL] [Abstract][Full Text] [Related]
19. Copy number loss of FBXW7 is related to gene expression and poor prognosis in esophageal squamous cell carcinoma.
Yokobori T; Mimori K; Iwatsuki M; Ishii H; Tanaka F; Sato T; Toh H; Sudo T; Iwaya T; Tanaka Y; Onoyama I; Kuwano H; Nakayama KI; Mori M
Int J Oncol; 2012 Jul; 41(1):253-9. PubMed ID: 22576686
[TBL] [Abstract][Full Text] [Related]
20. [Function and mechanism of tumor suppressor gene FBW7 in tumorigenesis].
Huang HJ; Zheng F; Xu FP; Liu YH; Zhuang HG
Zhonghua Bing Li Xue Za Zhi; 2013 Mar; 42(3):214-6. PubMed ID: 23769449
[No Abstract] [Full Text] [Related]
[Next] [New Search]