These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

266 related articles for article (PubMed ID: 22666431)

  • 1. Retigeric acid B exhibits antitumor activity through suppression of nuclear factor-κB signaling in prostate cancer cells in vitro and in vivo.
    Liu YQ; Hu XY; Lu T; Cheng YN; Young CY; Yuan HQ; Lou HX
    PLoS One; 2012; 7(5):e38000. PubMed ID: 22666431
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.
    Yadav VR; Prasad S; Gupta SC; Sung B; Phatak SS; Zhang S; Aggarwal BB
    J Biol Chem; 2012 Jan; 287(1):245-256. PubMed ID: 22065587
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice.
    Shanmugam MK; Rajendran P; Li F; Nema T; Vali S; Abbasi T; Kapoor S; Sharma A; Kumar AP; Ho PC; Hui KM; Sethi G
    J Mol Med (Berl); 2011 Jul; 89(7):713-27. PubMed ID: 21465181
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes.
    Shukla S; Gupta S
    Clin Cancer Res; 2004 May; 10(9):3169-78. PubMed ID: 15131058
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting nuclear factor-kappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis.
    Sethi G; Ahn KS; Aggarwal BB
    Mol Cancer Res; 2008 Jun; 6(6):1059-70. PubMed ID: 18567808
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.
    Shishodia S; Sethi G; Konopleva M; Andreeff M; Aggarwal BB
    Clin Cancer Res; 2006 Mar; 12(6):1828-38. PubMed ID: 16551868
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Trichothecin induces cell death in NF-κB constitutively activated human cancer cells via inhibition of IKKβ phosphorylation.
    Su J; Zhao P; Kong L; Li X; Yan J; Zeng Y; Li Y
    PLoS One; 2013; 8(8):e71333. PubMed ID: 23936501
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1.
    Shishodia S; Majumdar S; Banerjee S; Aggarwal BB
    Cancer Res; 2003 Aug; 63(15):4375-83. PubMed ID: 12907607
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Acetyl-11-keto-beta-boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-kappa B and NF-kappa B-regulated gene expression.
    Takada Y; Ichikawa H; Badmaev V; Aggarwal BB
    J Immunol; 2006 Mar; 176(5):3127-40. PubMed ID: 16493072
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis.
    Kunnumakkara AB; Ichikawa H; Anand P; Mohankumar CJ; Hema PS; Nair MS; Aggarwal BB
    Mol Cancer Ther; 2008 Oct; 7(10):3306-17. PubMed ID: 18852134
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Betulinic acid suppresses carcinogen-induced NF-kappa B activation through inhibition of I kappa B alpha kinase and p65 phosphorylation: abrogation of cyclooxygenase-2 and matrix metalloprotease-9.
    Takada Y; Aggarwal BB
    J Immunol; 2003 Sep; 171(6):3278-86. PubMed ID: 12960358
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alpha-tomatine attenuation of in vivo growth of subcutaneous and orthotopic xenograft tumors of human prostate carcinoma PC-3 cells is accompanied by inactivation of nuclear factor-kappa B signaling.
    Lee ST; Wong PF; He H; Hooper JD; Mustafa MR
    PLoS One; 2013; 8(2):e57708. PubMed ID: 23437404
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation.
    Sung B; Pandey MK; Aggarwal BB
    Mol Pharmacol; 2007 Jun; 71(6):1703-14. PubMed ID: 17387141
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PMS1077 sensitizes TNF-α induced apoptosis in human prostate cancer cells by blocking NF-κB signaling pathway.
    Shi J; Chen J; Serradji N; Xu X; Zhou H; Ma Y; Sun Z; Jiang P; Du Y; Yang J; Dong C; Wang Q
    PLoS One; 2013; 8(4):e61132. PubMed ID: 23593410
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products.
    Ichikawa H; Takada Y; Murakami A; Aggarwal BB
    J Immunol; 2005 Jun; 174(11):7383-92. PubMed ID: 15905586
    [TBL] [Abstract][Full Text] [Related]  

  • 16. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products.
    Shishodia S; Gutierrez AM; Lotan R; Aggarwal BB
    Cancer Res; 2005 Oct; 65(20):9555-65. PubMed ID: 16230421
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis.
    Takada Y; Singh S; Aggarwal BB
    J Biol Chem; 2004 Apr; 279(15):15096-104. PubMed ID: 14711835
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Betulinic Acid-Mediated Apoptosis in Human Prostate Cancer Cells Involves p53 and Nuclear Factor-Kappa B (NF-κB) Pathways.
    Shankar E; Zhang A; Franco D; Gupta S
    Molecules; 2017 Feb; 22(2):. PubMed ID: 28208611
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of IkappaB kinase activity by acetyl-boswellic acids promotes apoptosis in androgen-independent PC-3 prostate cancer cells in vitro and in vivo.
    Syrovets T; Gschwend JE; Büchele B; Laumonnier Y; Zugmaier W; Genze F; Simmet T
    J Biol Chem; 2005 Feb; 280(7):6170-80. PubMed ID: 15576374
    [TBL] [Abstract][Full Text] [Related]  

  • 20. β-elemonic acid inhibits growth and triggers apoptosis in human castration-resistant prostate cancer cells through the suppression of JAK2/STAT3/MCL-1 and NF-ĸB signal pathways.
    Bao X; Zhu J; Ren C; Zhao A; Zhang M; Zhu Z; Lu X; Zhang Y; Li X; Sima X; Li J; Zhang Q; Ma B
    Chem Biol Interact; 2021 Jun; 342():109477. PubMed ID: 33878321
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.