BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 22673163)

  • 1. Activated O2(•−) and H2O2 mediated cell survival in SU11274-treated non-small-cell lung cancer A549 cells via c-Met-PI3K-Akt and c-Met-Grb2/SOS-Ras-p38 pathways.
    Liu Y; Shi QF; Ye YC; Tashiro S; Onodera S; Ikejima T
    J Pharmacol Sci; 2012; 119(2):150-9. PubMed ID: 22673163
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of ERK-p53 and ERK-mediated phosphorylation of Bcl-2 are involved in autophagic cell death induced by the c-Met inhibitor SU11274 in human lung cancer A549 cells.
    Liu Y; Yang Y; Ye YC; Shi QF; Chai K; Tashiro S; Onodera S; Ikejima T
    J Pharmacol Sci; 2012; 118(4):423-32. PubMed ID: 22466960
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interruption of mitochondrial complex IV activity and cytochrome c expression activated O₂·⁻-mediated cell survival in silibinin-treated human melanoma A375-S2 cells via IGF-1R-PI3K-Akt and IGF-1R-PLC γ-PKC pathways.
    Jiang YY; Huang H; Wang HJ; Wu D; Yang R; Tashiro S; Onodera S; Ikejima T
    Eur J Pharmacol; 2011 Oct; 668(1-2):78-87. PubMed ID: 21703257
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells.
    Jagadeeswaran R; Jagadeeswaran S; Bindokas VP; Salgia R
    Am J Physiol Lung Cell Mol Physiol; 2007 Jun; 292(6):L1488-94. PubMed ID: 17322284
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reactive oxygen species H2O2 and •OH, but not O2•(-) promote oridonin-induced phagocytosis of apoptotic cells by human histocytic lymphoma U937 cells.
    Zang L; He H; Xu Q; Yu Y; Zheng N; Liu W; Hayashi T; Tashiro S; Onodera S; Ikejima T
    Int Immunopharmacol; 2013 Feb; 15(2):414-23. PubMed ID: 23352441
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells.
    Wang F; Li H; Yan XG; Zhou ZW; Yi ZG; He ZX; Pan ST; Yang YX; Wang ZZ; Zhang X; Yang T; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():575-601. PubMed ID: 25632225
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells.
    Nagappan A; Lee WS; Yun JW; Lu JN; Chang SH; Jeong JH; Kim GS; Jung JM; Hong SC
    PLoS One; 2017; 12(3):e0174591. PubMed ID: 28355296
    [TBL] [Abstract][Full Text] [Related]  

  • 9. c-Met is a potentially new therapeutic target for treatment of human melanoma.
    Puri N; Ahmed S; Janamanchi V; Tretiakova M; Zumba O; Krausz T; Jagadeeswaran R; Salgia R
    Clin Cancer Res; 2007 Apr; 13(7):2246-53. PubMed ID: 17404109
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
    Pan ST; Qin Y; Zhou ZW; He ZX; Zhang X; Yang T; Yang YX; Wang D; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1601-26. PubMed ID: 25834400
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Silibinin activated p53 and induced autophagic death in human fibrosarcoma HT1080 cells via reactive oxygen species-p38 and c-Jun N-terminal kinase pathways.
    Duan WJ; Li QS; Xia MY; Tashiro S; Onodera S; Ikejima T
    Biol Pharm Bull; 2011; 34(1):47-53. PubMed ID: 21212516
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Opposite effects of Ha-Ras and Ki-Ras on radiation-induced apoptosis via differential activation of PI3K/Akt and Rac/p38 mitogen-activated protein kinase signaling pathways.
    Choi JA; Park MT; Kang CM; Um HD; Bae S; Lee KH; Kim TH; Kim JH; Cho CK; Lee YS; Chung HY; Lee SJ
    Oncogene; 2004 Jan; 23(1):9-20. PubMed ID: 14712206
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation, and motility of lung endothelial cells.
    Usatyuk PV; Fu P; Mohan V; Epshtein Y; Jacobson JR; Gomez-Cambronero J; Wary KK; Bindokas V; Dudek SM; Salgia R; Garcia JG; Natarajan V
    J Biol Chem; 2014 May; 289(19):13476-91. PubMed ID: 24634221
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer.
    Ma PC; Jagadeeswaran R; Jagadeesh S; Tretiakova MS; Nallasura V; Fox EA; Hansen M; Schaefer E; Naoki K; Lader A; Richards W; Sugarbaker D; Husain AN; Christensen JG; Salgia R
    Cancer Res; 2005 Feb; 65(4):1479-88. PubMed ID: 15735036
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Preferential binding of Grb2 or phosphatidylinositol 3-kinase to the met receptor has opposite effects on HGF-induced myoblast proliferation.
    Leshem Y; Gitelman I; Ponzetto C; Halevy O
    Exp Cell Res; 2002 Apr; 274(2):288-98. PubMed ID: 11900489
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inactivated Sendai virus induces apoptosis and autophagy via the PI3K/Akt/mTOR/p70S6K pathway in human non-small cell lung cancer cells.
    Zhang Q; Zhu H; Xu X; Li L; Tan H; Cai X
    Biochem Biophys Res Commun; 2015 Sep; 465(1):64-70. PubMed ID: 26235873
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential role of hydrogen peroxide in UV-induced signal transduction.
    Ding M; Li J; Leonard SS; Shi X; Costa M; Castranova V; Vallyathan V; Huang C
    Mol Cell Biochem; 2002; 234-235(1-2):81-90. PubMed ID: 12162463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of c-Met with the specific small molecule tyrosine kinase inhibitor SU11274 decreases growth and metastasis formation of experimental human melanoma.
    Kenessey I; Keszthelyi M; Krámer Z; Berta J; Adám A; Dobos J; Mildner M; Flachner B; Cseh S; Barna G; Szokol B; Orfi L; Kéri G; Döme B; Klepetko W; Tímár J; Tóvári J
    Curr Cancer Drug Targets; 2010 May; 10(3):332-42. PubMed ID: 20370683
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oxyresveratrol activates parallel apoptotic and autophagic cell death pathways in neuroblastoma cells.
    Rahman MA; Bishayee K; Sadra A; Huh SO
    Biochim Biophys Acta Gen Subj; 2017 Feb; 1861(2):23-36. PubMed ID: 27815218
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Involvement of c-Met- and phosphatidylinositol 3-kinase dependent pathways in arsenite-induced downregulation of catalase in hepatoma cells.
    Kim S; Lee SH; Kang S; Lee L; Park JD; Ryu DY
    Biol Pharm Bull; 2011; 34(11):1748-52. PubMed ID: 22040890
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.