341 related articles for article (PubMed ID: 22673503)
1. Mdm2 and MdmX partner to regulate p53.
Wang X; Jiang X
FEBS Lett; 2012 May; 586(10):1390-6. PubMed ID: 22673503
[TBL] [Abstract][Full Text] [Related]
2. p53 regulation: teamwork between RING domains of Mdm2 and MdmX.
Wang X
Cell Cycle; 2011 Dec; 10(24):4225-9. PubMed ID: 22134240
[TBL] [Abstract][Full Text] [Related]
3. MdmX protein is essential for Mdm2 protein-mediated p53 polyubiquitination.
Wang X; Wang J; Jiang X
J Biol Chem; 2011 Jul; 286(27):23725-34. PubMed ID: 21572037
[TBL] [Abstract][Full Text] [Related]
4. Regulation of Mdm2 protein stability and the p53 response by NEDD4-1 E3 ligase.
Xu C; Fan CD; Wang X
Oncogene; 2015 Jan; 34(3):281-9. PubMed ID: 24413081
[TBL] [Abstract][Full Text] [Related]
5. MDMX Recruits UbcH5c to Facilitate MDM2 E3 Ligase Activity and Subsequent p53 Degradation
Yang J; Jin A; Han J; Chen X; Zheng J; Zhang Y
Cancer Res; 2021 Feb; 81(4):898-909. PubMed ID: 33277368
[TBL] [Abstract][Full Text] [Related]
6. Inactivation of the MDM2 RING domain enhances p53 transcriptional activity in mice.
Tian H; Tackmann NR; Jin A; Zheng J; Zhang Y
J Biol Chem; 2017 Dec; 292(52):21614-21622. PubMed ID: 29123033
[TBL] [Abstract][Full Text] [Related]
7. Interplay between MDM2, MDMX, Pirh2 and COP1: the negative regulators of p53.
Wang L; He G; Zhang P; Wang X; Jiang M; Yu L
Mol Biol Rep; 2011 Jan; 38(1):229-36. PubMed ID: 20333547
[TBL] [Abstract][Full Text] [Related]
8. Functional analysis and consequences of Mdm2 E3 ligase inhibition in human tumor cells.
Wade M; Li YC; Matani AS; Braun SM; Milanesi F; Rodewald LW; Wahl GM
Oncogene; 2012 Nov; 31(45):4789-97. PubMed ID: 22266850
[TBL] [Abstract][Full Text] [Related]
9. Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells.
Wu W; Xu C; Ling X; Fan C; Buckley BP; Chernov MV; Ellis L; Li F; Muñoz IG; Wang X
Cell Death Dis; 2015 Dec; 6(12):e2035. PubMed ID: 26720344
[TBL] [Abstract][Full Text] [Related]
10. Overexpression of Mdm2 and MdmX fusion proteins alters p53 mediated transactivation, ubiquitination, and degradation.
Ghosh M; Huang K; Berberich SJ
Biochemistry; 2003 Mar; 42(8):2291-9. PubMed ID: 12600196
[TBL] [Abstract][Full Text] [Related]
11. A site-directed mutagenesis study of the MdmX RING domain.
Egorova O; Mis M; Sheng Y
Biochem Biophys Res Commun; 2014 May; 447(4):696-701. PubMed ID: 24755078
[TBL] [Abstract][Full Text] [Related]
12. Critical contribution of the MDM2 acidic domain to p53 ubiquitination.
Kawai H; Wiederschain D; Yuan ZM
Mol Cell Biol; 2003 Jul; 23(14):4939-47. PubMed ID: 12832479
[TBL] [Abstract][Full Text] [Related]
13. Regulation of p53: a collaboration between Mdm2 and Mdmx.
Pei D; Zhang Y; Zheng J
Oncotarget; 2012 Mar; 3(3):228-35. PubMed ID: 22410433
[TBL] [Abstract][Full Text] [Related]
14. RING domain-mediated interaction is a requirement for MDM2's E3 ligase activity.
Kawai H; Lopez-Pajares V; Kim MM; Wiederschain D; Yuan ZM
Cancer Res; 2007 Jul; 67(13):6026-30. PubMed ID: 17616658
[TBL] [Abstract][Full Text] [Related]
15. MDMX is essential for the regulation of p53 protein levels in the absence of a functional MDM2 C-terminal tail.
Sanford JD; Yang J; Han J; Tollini LA; Jin A; Zhang Y
BMC Mol Cell Biol; 2021 Sep; 22(1):46. PubMed ID: 34551723
[TBL] [Abstract][Full Text] [Related]
16. Smad ubiquitylation regulatory factor 1/2 (Smurf1/2) promotes p53 degradation by stabilizing the E3 ligase MDM2.
Nie J; Xie P; Liu L; Xing G; Chang Z; Yin Y; Tian C; He F; Zhang L
J Biol Chem; 2010 Jul; 285(30):22818-30. PubMed ID: 20484049
[TBL] [Abstract][Full Text] [Related]
17. Mdm2 and MdmX RING Domains Play Distinct Roles in the Regulation of p53 Responses: A Comparative Study of Mdm2 and MdmX RING Domains in U2OS Cells.
Egorova O; Lau HH; McGraphery K; Sheng Y
Int J Mol Sci; 2020 Feb; 21(4):. PubMed ID: 32075226
[TBL] [Abstract][Full Text] [Related]
18. Effects of MdmX on Mdm2-mediated downregulation of pRB.
Uchida C; Miwa S; Isobe T; Kitagawa K; Hattori T; Oda T; Yasuda H; Kitagawa M
FEBS Lett; 2006 Mar; 580(7):1753-8. PubMed ID: 16510145
[TBL] [Abstract][Full Text] [Related]
19. Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase.
Okamoto K; Taya Y; Nakagama H
FEBS Lett; 2009 Sep; 583(17):2710-4. PubMed ID: 19619542
[TBL] [Abstract][Full Text] [Related]
20. ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation.
Meulmeester E; Pereg Y; Shiloh Y; Jochemsen AG
Cell Cycle; 2005 Sep; 4(9):1166-70. PubMed ID: 16082221
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
