These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 22674575)

  • 1. Cdc37/Hsp90 protein complex disruption triggers an autophagic clearance cascade for TDP-43 protein.
    Jinwal UK; Abisambra JF; Zhang J; Dharia S; O'Leary JC; Patel T; Braswell K; Jani T; Gestwicki JE; Dickey CA
    J Biol Chem; 2012 Jul; 287(29):24814-20. PubMed ID: 22674575
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Hsp90 kinase co-chaperone Cdc37 regulates tau stability and phosphorylation dynamics.
    Jinwal UK; Trotter JH; Abisambra JF; Koren J; Lawson LY; Vestal GD; O'Leary JC; Johnson AG; Jin Y; Jones JR; Li Q; Weeber EJ; Dickey CA
    J Biol Chem; 2011 May; 286(19):16976-83. PubMed ID: 21367866
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of celastrol to inhibit hsp90 and cdc37 interaction.
    Zhang T; Li Y; Yu Y; Zou P; Jiang Y; Sun D
    J Biol Chem; 2009 Dec; 284(51):35381-9. PubMed ID: 19858214
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Canonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complex.
    Erazo T; Moreno A; Ruiz-Babot G; Rodríguez-Asiain A; Morrice NA; Espadamala J; Bayascas JR; Gómez N; Lizcano JM
    Mol Cell Biol; 2013 Apr; 33(8):1671-86. PubMed ID: 23428871
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hsp90·Cdc37 Complexes with Protein Kinases Form Cooperatively with Multiple Distinct Interaction Sites.
    Eckl JM; Scherr MJ; Freiburger L; Daake MA; Sattler M; Richter K
    J Biol Chem; 2015 Dec; 290(52):30843-54. PubMed ID: 26511315
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Specific regulation of noncanonical p38alpha activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte.
    Ota A; Zhang J; Ping P; Han J; Wang Y
    Circ Res; 2010 Apr; 106(8):1404-12. PubMed ID: 20299663
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Serine/Threonine Kinase Unc-51-like Kinase-1 (Ulk1) Phosphorylates the Co-chaperone Cell Division Cycle Protein 37 (Cdc37) and Thereby Disrupts the Stability of Cdc37 Client Proteins.
    Li R; Yuan F; Fu W; Zhang L; Zhang N; Wang Y; Ma K; Li X; Wang L; Zhu WG; Zhao Y
    J Biol Chem; 2017 Feb; 292(7):2830-2841. PubMed ID: 28073914
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Split Renilla luciferase protein fragment-assisted complementation (SRL-PFAC) to characterize Hsp90-Cdc37 complex and identify critical residues in protein/protein interactions.
    Jiang Y; Bernard D; Yu Y; Xie Y; Zhang T; Li Y; Burnett JP; Fu X; Wang S; Sun D
    J Biol Chem; 2010 Jul; 285(27):21023-36. PubMed ID: 20413594
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The human Cdc37.Hsp90 complex studied by heteronuclear NMR spectroscopy.
    Sreeramulu S; Jonker HR; Langer T; Richter C; Lancaster CR; Schwalbe H
    J Biol Chem; 2009 Feb; 284(6):3885-96. PubMed ID: 19073599
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting CDC37: an alternative, kinase-directed strategy for disruption of oncogenic chaperoning.
    Smith JR; Workman P
    Cell Cycle; 2009 Feb; 8(3):362-72. PubMed ID: 19177013
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The chaperones Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail.
    Gould CM; Kannan N; Taylor SS; Newton AC
    J Biol Chem; 2009 Feb; 284(8):4921-35. PubMed ID: 19091746
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression and purification of recombinant NRL-Hsp90α and Cdc37-CRL proteins for in vitro Hsp90/Cdc37 inhibitors screening.
    He J; Niu X; Hu C; Zhang H; Guo Y; Ge Y; Wang G; Jiang Y
    Protein Expr Purif; 2013 Nov; 92(1):119-27. PubMed ID: 24056254
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Signal responsiveness of IkappaB kinases is determined by Cdc37-assisted transient interaction with Hsp90.
    Hinz M; Broemer M; Arslan SC; Otto A; Mueller EC; Dettmer R; Scheidereit C
    J Biol Chem; 2007 Nov; 282(44):32311-9. PubMed ID: 17728246
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The driver of malignancy in KG-1a leukemic cells, FGFR1OP2-FGFR1, encodes an HSP90 addicted oncoprotein.
    Jin Y; Zhen Y; Haugsten EM; Wiedlocha A
    Cell Signal; 2011 Nov; 23(11):1758-66. PubMed ID: 21745565
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cdc37/Hsp90 protein-mediated regulation of IRE1α protein activity in endoplasmic reticulum stress response and insulin synthesis in INS-1 cells.
    Ota A; Wang Y
    J Biol Chem; 2012 Feb; 287(9):6266-74. PubMed ID: 22199355
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of Novel Celastrol Derivatives as Hsp90-Cdc37 Interaction Disruptors with Antitumor Activity.
    Li N; Xu M; Wang B; Shi Z; Zhao Z; Tang Y; Wang X; Sun J; Chen L
    J Med Chem; 2019 Dec; 62(23):10798-10815. PubMed ID: 31725288
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and bioevaluation of inhibitors targeting HSP90-CDC37 protein-protein interaction based on a hydrophobic core.
    Zhang Q; Wu X; Zhou J; Zhang L; Xu X; Zhang L; You Q; Wang L
    Eur J Med Chem; 2021 Jan; 210():112959. PubMed ID: 33109397
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Apigenin inhibits proliferation and induces apoptosis in human multiple myeloma cells through targeting the trinity of CK2, Cdc37 and Hsp90.
    Zhao M; Ma J; Zhu HY; Zhang XH; Du ZY; Xu YJ; Yu XD
    Mol Cancer; 2011 Aug; 10():104. PubMed ID: 21871133
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1.
    Gaude H; Aznar N; Delay A; Bres A; Buchet-Poyau K; Caillat C; Vigouroux A; Rogon C; Woods A; Vanacker JM; Höhfeld J; Perret C; Meyer P; Billaud M; Forcet C
    Oncogene; 2012 Mar; 31(12):1582-91. PubMed ID: 21860411
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The CDC37-HSP90 chaperone complex co-translationally degrades the nascent kinase-dead mutant of HIPK2.
    Müller JP; Klempnauer KH
    FEBS Lett; 2021 Jun; 595(11):1559-1568. PubMed ID: 33786814
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.