These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 22677490)

  • 1. The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci.
    Mok MT; Henderson BR
    Int J Biochem Cell Biol; 2012 Sep; 44(9):1398-409. PubMed ID: 22677490
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Downregulation of MDC1 and 53BP1 by short hairpin RNA enhances radiosensitivity in laryngeal carcinoma cells.
    Gou Q; Xie Y; Liu L; Xie K; Wu Y; Wang Q; Wang Z; Li P
    Oncol Rep; 2015 Jul; 34(1):251-7. PubMed ID: 25976740
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Three-dimensional imaging reveals the spatial separation of γH2AX-MDC1-53BP1 and RNF8-RNF168-BRCA1-A complexes at ionizing radiation-induced foci.
    Mok MT; Henderson BR
    Radiother Oncol; 2012 Jun; 103(3):415-20. PubMed ID: 22633816
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours.
    Bartkova J; Horejsí Z; Sehested M; Nesland JM; Rajpert-De Meyts E; Skakkebaek NE; Stucki M; Jackson S; Lukas J; Bartek J
    Oncogene; 2007 Nov; 26(53):7414-22. PubMed ID: 17546051
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage.
    Mochan TA; Venere M; DiTullio RA; Halazonetis TD
    Cancer Res; 2003 Dec; 63(24):8586-91. PubMed ID: 14695167
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The direct interaction between 53BP1 and MDC1 is required for the recruitment of 53BP1 to sites of damage.
    Eliezer Y; Argaman L; Rhie A; Doherty AJ; Goldberg M
    J Biol Chem; 2009 Jan; 284(1):426-435. PubMed ID: 18986980
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1.
    Bekker-Jensen S; Lukas C; Melander F; Bartek J; Lukas J
    J Cell Biol; 2005 Jul; 170(2):201-11. PubMed ID: 16009723
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutations in the TP53 gene affected recruitment of 53BP1 protein to DNA lesions, but level of 53BP1 was stable after γ-irradiation that depleted MDC1 protein in specific TP53 mutants.
    Suchánková J; Legartová S; Ručková E; Vojtěšek B; Kozubek S; Bártová E
    Histochem Cell Biol; 2017 Sep; 148(3):239-255. PubMed ID: 28397142
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A comparison of BRCA1 nuclear localization with 14 DNA damage response proteins and domains: identification of specific differences between BRCA1 and 53BP1 at DNA damage-induced foci.
    Mok MT; Henderson BR
    Cell Signal; 2010 Jan; 22(1):47-56. PubMed ID: 19766185
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 53BP1 and MDC1 foci formation in HT-1080 cells for low- and high-LET microbeam irradiations.
    Mosconi M; Giesen U; Langner F; Mielke C; Dalla Rosa I; Dirks WG
    Radiat Environ Biophys; 2011 Aug; 50(3):345-52. PubMed ID: 21559952
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recruitment kinetics of DNA repair proteins Mdc1 and Rad52 but not 53BP1 depend on damage complexity.
    Hable V; Drexler GA; Brüning T; Burgdorf C; Greubel C; Derer A; Seel J; Strickfaden H; Cremer T; Friedl AA; Dollinger G
    PLoS One; 2012; 7(7):e41943. PubMed ID: 22860035
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors.
    Xu X; Stern DF
    FASEB J; 2003 Oct; 17(13):1842-8. PubMed ID: 14519663
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NFBD1/Mdc1 mediates ATR-dependent DNA damage response.
    Peng A; Chen PL
    Cancer Res; 2005 Feb; 65(4):1158-63. PubMed ID: 15734998
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage.
    Peng A; Chen PL
    J Biol Chem; 2003 Mar; 278(11):8873-6. PubMed ID: 12551934
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway.
    Wilson KA; Stern DF
    Cell Cycle; 2008 Nov; 7(22):3584-94. PubMed ID: 19001859
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differences in DNA double strand breaks repair in male germ cell types: lessons learned from a differential expression of Mdc1 and 53BP1.
    Ahmed EA; van der Vaart A; Barten A; Kal HB; Chen J; Lou Z; Minter-Dykhouse K; Bartkova J; Bartek J; de Boer P; de Rooij DG
    DNA Repair (Amst); 2007 Sep; 6(9):1243-54. PubMed ID: 17376750
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Recruitment of proteins to DNA double-strand breaks: MDC1 directly recruits RAP80.
    Strauss C; Goldberg M
    Cell Cycle; 2011 Sep; 10(17):2850-7. PubMed ID: 21857162
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Knockdown of Minichromosome Maintenance Proteins Inhibits Foci Forming of Mediator of DNA-Damage Checkpoint 1 in Response to DNA Damage in Human Esophageal Squamous Cell Carcinoma TE-1 Cells.
    Yu J; Wang R; Wu J; Dang Z; Zhang Q; Li B
    Biochemistry (Mosc); 2016 Oct; 81(10):1221-1228. PubMed ID: 27908247
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Expression of DNA damage checkpoint mediator 1 and p53-binding protein 1 in human esophageal cancer cell lines TE-1, TE-13, and Eca109].
    Liu ZK; Zhu SC; Wang YX
    Nan Fang Yi Ke Da Xue Xue Bao; 2007 Sep; 27(9):1314-7. PubMed ID: 17884766
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sumoylation of MDC1 is important for proper DNA damage response.
    Luo K; Zhang H; Wang L; Yuan J; Lou Z
    EMBO J; 2012 Jun; 31(13):3008-19. PubMed ID: 22635276
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.