177 related articles for article (PubMed ID: 22678811)
1. A novel long-acting human growth hormone fusion protein (VRS-317): enhanced in vivo potency and half-life.
Cleland JL; Geething NC; Moore JA; Rogers BC; Spink BJ; Wang CW; Alters SE; Stemmer WP; Schellenberger V
J Pharm Sci; 2012 Aug; 101(8):2744-54. PubMed ID: 22678811
[TBL] [Abstract][Full Text] [Related]
2. A long-acting human growth hormone with delayed clearance (VRS-317): results of a double-blind, placebo-controlled, single ascending dose study in growth hormone-deficient adults.
Yuen KC; Conway GS; Popovic V; Merriam GR; Bailey T; Hamrahian AH; Biller BM; Kipnes M; Moore JA; Humphriss E; Bright GM; Cleland JL
J Clin Endocrinol Metab; 2013 Jun; 98(6):2595-603. PubMed ID: 23585663
[TBL] [Abstract][Full Text] [Related]
3. Pharmacokinetics, Pharmacodynamics, and Efficacy of a Novel Long-Acting Human Growth Hormone: Fc Fusion Protein.
Kim SJ; Kwak HH; Cho SY; Sohn YB; Park SW; Huh R; Kim J; Ko AR; Jin DK
Mol Pharm; 2015 Oct; 12(10):3759-65. PubMed ID: 26370910
[TBL] [Abstract][Full Text] [Related]
4. In Vitro and in Vivo Characterization of MOD-4023, a Long-Acting Carboxy-Terminal Peptide (CTP)-Modified Human Growth Hormone.
Hershkovitz O; Bar-Ilan A; Guy R; Felikman Y; Moschcovich L; Hwa V; Rosenfeld RG; Fima E; Hart G
Mol Pharm; 2016 Feb; 13(2):631-9. PubMed ID: 26713839
[TBL] [Abstract][Full Text] [Related]
5. Human growth hormone expressed in tobacco cells as an arabinogalactan-protein fusion glycoprotein has a prolonged serum life.
Xu J; Okada S; Tan L; Goodrum KJ; Kopchick JJ; Kieliszewski MJ
Transgenic Res; 2010 Oct; 19(5):849-67. PubMed ID: 20135224
[TBL] [Abstract][Full Text] [Related]
6. Albutropin: a growth hormone-albumin fusion with improved pharmacokinetics and pharmacodynamics in rats and monkeys.
Osborn BL; Sekut L; Corcoran M; Poortman C; Sturm B; Chen G; Mather D; Lin HL; Parry TJ
Eur J Pharmacol; 2002 Dec; 456(1-3):149-58. PubMed ID: 12450581
[TBL] [Abstract][Full Text] [Related]
7. Impact of experimental blockade of peripheral growth hormone (GH) receptors on the kinetics of endogenous and exogenous GH removal in healthy women and men.
Veldhuis JD; Bidlingmaier M; Anderson SM; Evans WS; Wu Z; Strasburger CJ
J Clin Endocrinol Metab; 2002 Dec; 87(12):5737-45. PubMed ID: 12466380
[TBL] [Abstract][Full Text] [Related]
8. Recombinant human growth hormone (GH)-binding protein enhances the growth-promoting activity of human GH in the rat.
Clark RG; Mortensen DL; Carlsson LM; Spencer SA; McKay P; Mulkerrin M; Moore J; Cunningham BC
Endocrinology; 1996 Oct; 137(10):4308-15. PubMed ID: 8828490
[TBL] [Abstract][Full Text] [Related]
9. Development of a sustained-release recombinant human growth hormone formulation.
Kwak HH; Shim WS; Choi MK; Son MK; Kim YJ; Yang HC; Kim TH; Lee GI; Kim BM; Kang SH; Shim CK
J Control Release; 2009 Jul; 137(2):160-5. PubMed ID: 19332090
[TBL] [Abstract][Full Text] [Related]
10. Equivalent potency and pharmacokinetics of recombinant human growth hormones with or without an N-terminal methionine.
Moore JA; Rudman CG; MacLachlan NJ; Fuller GB; Burnett B; Frane JW
Endocrinology; 1988 Jun; 122(6):2920-6. PubMed ID: 3371267
[TBL] [Abstract][Full Text] [Related]
11. A Superlong-Acting Growth Hormone-Polypeptide Fusion for Growth Hormone Deficiency Treatment.
Yang Z; Yao Q; Gong L; Zhang F; Sun J; Sun Y; Gao W
Adv Healthc Mater; 2024 Feb; 13(5):e2302507. PubMed ID: 38030143
[TBL] [Abstract][Full Text] [Related]
12. Sensitivity to exogenous GH and reversibility of the reduced IGF-I gene expression in aging rats.
Velasco B; Cacicedo L; Melian E; Fernández-Vázquez G; Sánchez-Franco F
Eur J Endocrinol; 2001 Jul; 145(1):73-85. PubMed ID: 11415855
[TBL] [Abstract][Full Text] [Related]
13. A novel sustained-release formulation of recombinant human growth hormone and its pharmacokinetic, pharmacodynamic and safety profiles.
Wei Y; Wang Y; Kang A; Wang W; Ho SV; Gao J; Ma G; Su Z
Mol Pharm; 2012 Jul; 9(7):2039-48. PubMed ID: 22663348
[TBL] [Abstract][Full Text] [Related]
14. A pharmacokinetic/pharmacodynamic model for recombinant human growth hormone effects on induction of insulin-like growth factor I in monkeys.
Sun YN; Lee HJ; Almon RR; Jusko WJ
J Pharmacol Exp Ther; 1999 Jun; 289(3):1523-32. PubMed ID: 10336548
[TBL] [Abstract][Full Text] [Related]
15. Comparative pharmacokinetics and pharmacodynamics of a PEGylated recombinant human growth hormone and daily recombinant human growth hormone in growth hormone-deficient children.
Hou L; Chen ZH; Liu D; Cheng YG; Luo XP
Drug Des Devel Ther; 2016; 10():13-21. PubMed ID: 26719670
[TBL] [Abstract][Full Text] [Related]
16. Nonclinical pharmacokinetic and pharmacodynamic characterisation of somapacitan: A reversible non-covalent albumin-binding growth hormone.
Thygesen P; Andersen HS; Behrens C; Fels JJ; Nørskov-Lauritsen L; Rischel C; Johansen NL
Growth Horm IGF Res; 2017 Aug; 35():8-16. PubMed ID: 28595133
[TBL] [Abstract][Full Text] [Related]
17. Abuse of recombinant human growth hormone: studies in two different dog models.
Rigamonti AE; Scanniffio D; Bonomo SM; Cella SG; Sartorio A; Müller EE
Neuroendocrinology; 2004; 79(5):237-46. PubMed ID: 15218318
[TBL] [Abstract][Full Text] [Related]
18. Pharmacokinetic/pharmacodynamic (PK/PD) differentiation of native and PEGylated recombinant human growth hormone (rhGH and PEG-rhGH) in the rat model of osteoarthritis.
Nemirovskiy O; Zheng YJ; Tung D; Korniski B; Settle S; Skepner A; Yates M; Aggarwal P; Sunyer T; Aguiar DJ
Xenobiotica; 2010 Aug; 40(8):586-92. PubMed ID: 20509748
[TBL] [Abstract][Full Text] [Related]
19. Improving the pharmacokinetics/pharmacodynamics of prolactin, GH, and their antagonists by fusion to a synthetic albumin-binding peptide.
Langenheim JF; Chen WY
J Endocrinol; 2009 Dec; 203(3):375-87. PubMed ID: 19770179
[TBL] [Abstract][Full Text] [Related]
20. Novel assays based on human growth hormone receptor as alternatives to the rat weight gain bioassay for recombinant human growth hormone.
Roswall EC; Mukku VR; Chen AB; Hoff EH; Chu H; McKay PA; Olson KC; Battersby JE; Gehant RL; Meunier A; Garnick RL
Biologicals; 1996 Mar; 24(1):25-39. PubMed ID: 8733599
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
