BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 22679499)

  • 1. Mammalian glutaminase Gls2 gene encodes two functional alternative transcripts by a surrogate promoter usage mechanism.
    Martín-Rufián M; Tosina M; Campos-Sandoval JA; Manzanares E; Lobo C; Segura JA; Alonso FJ; Matés JM; Márquez J
    PLoS One; 2012; 7(6):e38380. PubMed ID: 22679499
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Epigenetic silencing of glutaminase 2 in human liver and colon cancers.
    Zhang J; Wang C; Chen M; Cao J; Zhong Y; Chen L; Shen HM; Xia D
    BMC Cancer; 2013 Dec; 13():601. PubMed ID: 24330717
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural organization of the human complexin 2 gene (CPLX2) and aspects of its functional activity.
    Raevskaya NM; Dergunova LV; Vladychenskaya IP; Stavchansky VV; Oborina MV; Poltaraus AB; Limborska SA
    Gene; 2005 Oct; 359():127-37. PubMed ID: 16162394
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transcription factor GATA3 expression is induced by GLS2 overexpression in a glioblastoma cell line but is GLS2-independent in patient-derived glioblastoma.
    Majewska E; Rola R; Barczewska M; Marquez J; Albrecht J; Szeliga M
    J Physiol Pharmacol; 2017 Apr; 68(2):209-214. PubMed ID: 28614770
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells.
    Lee YZ; Yang CW; Chang HY; Hsu HY; Chen IS; Chang HS; Lee CH; Lee JC; Kumar CR; Qiu YQ; Chao YS; Lee SJ
    Oncotarget; 2014 Aug; 5(15):6087-101. PubMed ID: 25026281
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PPARα Downregulates Hepatic Glutaminase Expression in Mice Fed Diets with Different Protein:Carbohydrate Ratios.
    Velázquez-Villegas LA; Charabati T; Contreras AV; Alemán G; Torres N; Tovar AR
    J Nutr; 2016 Sep; 146(9):1634-40. PubMed ID: 27466601
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genomic organization and transcriptional analysis of the human l-glutaminase gene.
    Pérez-Gómez C; Matés JM; Gómez-Fabre PM; del Castillo-Olivares A; Alonso FJ; Márquez J
    Biochem J; 2003 Mar; 370(Pt 3):771-84. PubMed ID: 12444921
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Silencing of GLS and overexpression of GLS2 genes cooperate in decreasing the proliferation and viability of glioblastoma cells.
    Szeliga M; Bogacińska-Karaś M; Różycka A; Hilgier W; Marquez J; Albrecht J
    Tumour Biol; 2014 Mar; 35(3):1855-62. PubMed ID: 24096582
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nuclear localization of L-type glutaminase in mammalian brain.
    Olalla L; Gutiérrez A; Campos JA; Khan ZU; Alonso FJ; Segura JA; Márquez J; Aledo JC
    J Biol Chem; 2002 Oct; 277(41):38939-44. PubMed ID: 12163477
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure and activation mechanism of the human liver-type glutaminase GLS2.
    Ferreira IM; Quesñay JEN; Bastos AC; Rodrigues CT; Vollmar M; Krojer T; Strain-Damerell C; Burgess-Brown NA; von Delft F; Yue WW; Dias SM; Ambrosio AL
    Biochimie; 2021 Jun; 185():96-104. PubMed ID: 33746066
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression of Gls and Gls2 glutaminase isoforms in astrocytes.
    Cardona C; Sánchez-Mejías E; Dávila JC; Martín-Rufián M; Campos-Sandoval JA; Vitorica J; Alonso FJ; Matés JM; Segura JA; Norenberg MD; Rama Rao KV; Jayakumar AR; Gutiérrez A; Márquez J
    Glia; 2015 Mar; 63(3):365-82. PubMed ID: 25297978
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer.
    Lukey MJ; Cluntun AA; Katt WP; Lin MJ; Druso JE; Ramachandran S; Erickson JW; Le HH; Wang ZE; Blank B; Greene KS; Cerione RA
    Cell Rep; 2019 Oct; 29(1):76-88.e7. PubMed ID: 31577957
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Downregulation of GLS2 in glioblastoma cells is related to DNA hypermethylation but not to the p53 status.
    Szeliga M; Bogacińska-Karaś M; Kuźmicz K; Rola R; Albrecht J
    Mol Carcinog; 2016 Sep; 55(9):1309-16. PubMed ID: 26258493
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2.
    Xiao D; Ren P; Su H; Yue M; Xiu R; Hu Y; Liu H; Qing G
    Oncotarget; 2015 Dec; 6(38):40655-66. PubMed ID: 26528759
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p63 regulates glutaminase 2 expression.
    Giacobbe A; Bongiorno-Borbone L; Bernassola F; Terrinoni A; Markert EK; Levine AJ; Feng Z; Agostini M; Zolla L; Agrò AF; Notterman DA; Melino G; Peschiaroli A
    Cell Cycle; 2013 May; 12(9):1395-405. PubMed ID: 23574722
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Opposing roles of glutaminase isoforms in determining glioblastoma cell phenotype.
    Szeliga M; Albrecht J
    Neurochem Int; 2015 Sep; 88():6-9. PubMed ID: 25529918
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Long non-coding RNA UCA1 promotes glutamine metabolism by targeting miR-16 in human bladder cancer.
    Li HJ; Li X; Pang H; Pan JJ; Xie XJ; Chen W
    Jpn J Clin Oncol; 2015 Nov; 45(11):1055-63. PubMed ID: 26373319
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, Synthesis, and Evaluation of Thiazolidine-2,4-dione Derivatives as a Novel Class of Glutaminase Inhibitors.
    Yeh TK; Kuo CC; Lee YZ; Ke YY; Chu KF; Hsu HY; Chang HY; Liu YW; Song JS; Yang CW; Lin LM; Sun M; Wu SH; Kuo PC; Shih C; Chen CT; Tsou LK; Lee SJ
    J Med Chem; 2017 Jul; 60(13):5599-5612. PubMed ID: 28609101
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species.
    Suzuki S; Tanaka T; Poyurovsky MV; Nagano H; Mayama T; Ohkubo S; Lokshin M; Hosokawa H; Nakayama T; Suzuki Y; Sugano S; Sato E; Nagao T; Yokote K; Tatsuno I; Prives C
    Proc Natl Acad Sci U S A; 2010 Apr; 107(16):7461-6. PubMed ID: 20351271
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lack of expression of the liver-type glutaminase (LGA) mRNA in human malignant gliomas.
    Szeliga M; Sidoryk M; Matyja E; Kowalczyk P; Albrecht J
    Neurosci Lett; 2005 Feb; 374(3):171-3. PubMed ID: 15663956
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.