BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 22681552)

  • 1. Glycoengineering approach to half-life extension of recombinant biotherapeutics.
    Chen C; Constantinou A; Chester KA; Vyas B; Canis K; Haslam SM; Dell A; Epenetos AA; Deonarain MP
    Bioconjug Chem; 2012 Aug; 23(8):1524-33. PubMed ID: 22681552
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Site-specific polysialylation of an antitumor single-chain Fv fragment.
    Constantinou A; Epenetos AA; Hreczuk-Hirst D; Jain S; Wright M; Chester KA; Deonarain MP
    Bioconjug Chem; 2009 May; 20(5):924-31. PubMed ID: 19402707
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Half-life extension of a single-chain diabody by fusion to domain B of staphylococcal protein A.
    Unverdorben F; Färber-Schwarz A; Richter F; Hutt M; Kontermann RE
    Protein Eng Des Sel; 2012 Feb; 25(2):81-8. PubMed ID: 22238430
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fusion of a recombinant antibody fragment with a homo-amino-acid polymer: effects on biophysical properties and prolonged plasma half-life.
    Schlapschy M; Theobald I; Mack H; Schottelius M; Wester HJ; Skerra A
    Protein Eng Des Sel; 2007 Jun; 20(6):273-84. PubMed ID: 17595342
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Highly efficient production of anti-HER2 scFv antibody variant for targeting breast cancer cells.
    Sommaruga S; Lombardi A; Salvadè A; Mazzucchelli S; Corsi F; Galeffi P; Tortora P; Prosperi D
    Appl Microbiol Biotechnol; 2011 Aug; 91(3):613-21. PubMed ID: 21538107
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An anti-TNFR1 scFv-HSA fusion protein as selective antagonist of TNF action.
    Berger V; Richter F; Zettlitz K; Unverdorben F; Scheurich P; Herrmann A; Pfizenmaier K; Kontermann RE
    Protein Eng Des Sel; 2013 Oct; 26(10):581-7. PubMed ID: 24006371
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Site-specific, covalent labeling of recombinant antibody fragments via fusion to an engineered version of 6-O-alkylguanine DNA alkyltransferase.
    Kampmeier F; Ribbert M; Nachreiner T; Dembski S; Beaufils F; Brecht A; Barth S
    Bioconjug Chem; 2009 May; 20(5):1010-5. PubMed ID: 19388673
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Construction, expression and characterization of the engineered antibody against tumor surface antigen, p185(c-erbB-2).
    Cheng LS; Liu AP; Yang JH; Dong YQ; Li LW; Wang J; Wang CC; Liu J
    Cell Res; 2003 Feb; 13(1):35-48. PubMed ID: 12643348
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The effects of affinity and valency of an albumin-binding domain (ABD) on the half-life of a single-chain diabody-ABD fusion protein.
    Hopp J; Hornig N; Zettlitz KA; Schwarz A; Fuss N; Müller D; Kontermann RE
    Protein Eng Des Sel; 2010 Nov; 23(11):827-34. PubMed ID: 20817756
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The IgM CH2 domain as covalently linked homodimerization module for the generation of fusion proteins with dual specificity.
    Seifert O; Plappert A; Heidel N; Fellermeier S; Messerschmidt SK; Richter F; Kontermann RE
    Protein Eng Des Sel; 2012 Oct; 25(10):603-12. PubMed ID: 22988132
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel bispecific tetravalent antibody fusion protein to target costimulatory activity for T-cell activation to tumor cells overexpressing ErbB2/HER2.
    Biburger M; Weth R; Wels WS
    J Mol Biol; 2005 Mar; 346(5):1299-311. PubMed ID: 15713482
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Construction and expression of human anti-HER2 scFv-9R fusion protein and identification of its activity].
    Jiang K; Chen R; Wang LF; Ma Q; Meng YL; Yang AG; Ma BA; Qiu XC
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2011 Nov; 27(11):1201-3. PubMed ID: 22078448
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antitumor effects of an engineered and energized fusion protein consisting of an anti-CD20 scFv fragment and lidamycin.
    Fang H; Miao Q; Zhang S; Cheng X; Xiong D; Zhen Y
    Sci China Life Sci; 2011 Mar; 54(3):255-62. PubMed ID: 21416325
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Preclinical screening of anti-HER2 nanobodies for molecular imaging of breast cancer.
    Vaneycken I; Devoogdt N; Van Gassen N; Vincke C; Xavier C; Wernery U; Muyldermans S; Lahoutte T; Caveliers V
    FASEB J; 2011 Jul; 25(7):2433-46. PubMed ID: 21478264
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fc engineering: serum half-life modulation through FcRn binding.
    Olafsen T
    Methods Mol Biol; 2012; 907():537-56. PubMed ID: 22907373
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Integration of PEGylation and refolding for renaturation of recombinant proteins from insoluble aggregates produced in bacteria--application to a single-chain Fv fragment.
    Kumagai I; Asano R; Nakanishi T; Hashikami K; Tanaka S; Badran A; Sanada H; Umetsu M
    J Biosci Bioeng; 2010 May; 109(5):447-52. PubMed ID: 20347766
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting and therapy of carcinoembryonic antigen-expressing tumors in transgenic mice with an antibody-interleukin 2 fusion protein.
    Xu X; Clarke P; Szalai G; Shively JE; Williams LE; Shyr Y; Shi E; Primus FJ
    Cancer Res; 2000 Aug; 60(16):4475-84. PubMed ID: 10969795
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined Fc-protein- and Fc-glyco-engineering of scFv-Fc fusion proteins synergistically enhances CD16a binding but does not further enhance NK-cell mediated ADCC.
    Repp R; Kellner C; Muskulus A; Staudinger M; Nodehi SM; Glorius P; Akramiene D; Dechant M; Fey GH; van Berkel PH; van de Winkel JG; Parren PW; Valerius T; Gramatzki M; Peipp M
    J Immunol Methods; 2011 Oct; 373(1-2):67-78. PubMed ID: 21855548
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Engineering of an anti-epidermal growth factor receptor antibody to single chain format and labeling by Sortase A-mediated protein ligation.
    Madej MP; Coia G; Williams CC; Caine JM; Pearce LA; Attwood R; Bartone NA; Dolezal O; Nisbet RM; Nuttall SD; Adams TE
    Biotechnol Bioeng; 2012 Jun; 109(6):1461-70. PubMed ID: 22170409
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacokinetics and biodistribution of genetically-engineered antibodies.
    Colcher D; Pavlinkova G; Beresford G; Booth BJ; Choudhury A; Batra SK
    Q J Nucl Med; 1998 Dec; 42(4):225-41. PubMed ID: 9973838
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.