BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

545 related articles for article (PubMed ID: 22683764)

  • 1. Tryptophan depletion in depressed patients occurs independent of kynurenine pathway activation.
    Hughes MM; Carballedo A; McLoughlin DM; Amico F; Harkin A; Frodl T; Connor TJ
    Brain Behav Immun; 2012 Aug; 26(6):979-87. PubMed ID: 22683764
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Altered tryptophan catabolite concentrations in major depressive disorder and associated changes in hippocampal subfield volumes.
    Doolin K; Allers KA; Pleiner S; Liesener A; Farrell C; Tozzi L; O'Hanlon E; Roddy D; Frodl T; Harkin A; O'Keane V
    Psychoneuroendocrinology; 2018 Sep; 95():8-17. PubMed ID: 29787958
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: a role for IFN-gamma?
    Connor TJ; Starr N; O'Sullivan JB; Harkin A
    Neurosci Lett; 2008 Aug; 441(1):29-34. PubMed ID: 18584961
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms.
    Schefold JC; Zeden JP; Fotopoulou C; von Haehling S; Pschowski R; Hasper D; Volk HD; Schuett C; Reinke P
    Nephrol Dial Transplant; 2009 Jun; 24(6):1901-8. PubMed ID: 19155537
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetic and hormonal regulation of tryptophan kynurenine metabolism: implications for vascular cognitive impairment, major depressive disorder, and aging.
    Oxenkrug GF
    Ann N Y Acad Sci; 2007 Dec; 1122():35-49. PubMed ID: 18077563
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The immune effects of TRYCATs (tryptophan catabolites along the IDO pathway): relevance for depression - and other conditions characterized by tryptophan depletion induced by inflammation.
    Maes M; Mihaylova I; Ruyter MD; Kubera M; Bosmans E
    Neuro Endocrinol Lett; 2007 Dec; 28(6):826-31. PubMed ID: 18063923
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of kynurenine pathway in ex vivo fibroblasts from patients with bipolar disorder or schizophrenia: cytokine challenge increases production of 3-hydroxykynurenine.
    Johansson AS; Owe-Larsson B; Asp L; Kocki T; Adler M; Hetta J; Gardner R; Lundkvist GB; Urbanska EM; Karlsson H
    J Psychiatr Res; 2013 Nov; 47(11):1815-23. PubMed ID: 24012176
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Network beyond IDO in psychiatric disorders: revisiting neurodegeneration hypothesis.
    Myint AM; Kim YK
    Prog Neuropsychopharmacol Biol Psychiatry; 2014 Jan; 48():304-13. PubMed ID: 24184687
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients.
    Schwieler L; Samuelsson M; Frye MA; Bhat M; Schuppe-Koistinen I; Jungholm O; Johansson AG; Landén M; Sellgren CM; Erhardt S
    J Neuroinflammation; 2016 Feb; 13(1):51. PubMed ID: 26925576
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ongoing episode of major depressive disorder is not associated with elevated plasma levels of kynurenine pathway markers.
    Dahl J; Andreassen OA; Verkerk R; Malt UF; Sandvik L; Brundin L; Ormstad H
    Psychoneuroendocrinology; 2015 Jun; 56():12-22. PubMed ID: 25770856
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Relationship between neurotoxic kynurenine metabolites and reductions in right medial prefrontal cortical thickness in major depressive disorder.
    Meier TB; Drevets WC; Wurfel BE; Ford BN; Morris HM; Victor TA; Bodurka J; Teague TK; Dantzer R; Savitz J
    Brain Behav Immun; 2016 Mar; 53():39-48. PubMed ID: 26546831
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IDO and interferon-alpha-induced depressive symptoms: a shift in hypothesis from tryptophan depletion to neurotoxicity.
    Wichers MC; Koek GH; Robaeys G; Verkerk R; Scharpé S; Maes M
    Mol Psychiatry; 2005 Jun; 10(6):538-44. PubMed ID: 15494706
    [TBL] [Abstract][Full Text] [Related]  

  • 13. C-reactive protein predicts fatigue independently of depression in breast cancer patients prior to chemotherapy.
    Pertl MM; Hevey D; Boyle NT; Hughes MM; Collier S; O'Dwyer AM; Harkin A; Kennedy MJ; Connor TJ
    Brain Behav Immun; 2013 Nov; 34():108-19. PubMed ID: 23928287
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Poly I:C-induced activation of the immune response is accompanied by depression and anxiety-like behaviours, kynurenine pathway activation and reduced BDNF expression.
    Gibney SM; McGuinness B; Prendergast C; Harkin A; Connor TJ
    Brain Behav Immun; 2013 Feb; 28():170-81. PubMed ID: 23201589
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tryptophan metabolism in chronic inflammatory lung disease.
    Meyer KC; Arend RA; Kalayoglu MV; Rosenthal NS; Byrne GI; Brown RR
    J Lab Clin Med; 1995 Dec; 126(6):530-40. PubMed ID: 7490512
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Does tryptophan degradation along the kynurenine pathway mediate the association between pro-inflammatory immune activity and depressive symptoms?
    Quak J; Doornbos B; Roest AM; Duivis HE; Vogelzangs N; Nolen WA; Penninx BW; Kema IP; de Jonge P
    Psychoneuroendocrinology; 2014 Jul; 45():202-10. PubMed ID: 24845191
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Involvement of the kynurenine pathway in human glioma pathophysiology.
    Adams S; Teo C; McDonald KL; Zinger A; Bustamante S; Lim CK; Sundaram G; Braidy N; Brew BJ; Guillemin GJ
    PLoS One; 2014; 9(11):e112945. PubMed ID: 25415278
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evaluation of indoleamine 2,3-dioxygenase expression and kynurenine pathway metabolites levels in serum samples of diabetic retinopathy patients.
    Munipally PK; Agraharm SG; Valavala VK; Gundae S; Turlapati NR
    Arch Physiol Biochem; 2011 Dec; 117(5):254-8. PubMed ID: 22034910
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The new '5-HT' hypothesis of depression: cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression.
    Maes M; Leonard BE; Myint AM; Kubera M; Verkerk R
    Prog Neuropsychopharmacol Biol Psychiatry; 2011 Apr; 35(3):702-21. PubMed ID: 21185346
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interaction of the immune-inflammatory and the kynurenine pathways in rats resistant to antidepressant treatment in model of depression.
    Duda W; Curzytek K; Kubera M; Connor TJ; Fagan EM; Basta-Kaim A; Trojan E; Papp M; Gruca P; Budziszewska B; Leśkiewicz M; Maes M; Lasoń W
    Int Immunopharmacol; 2019 Aug; 73():527-538. PubMed ID: 31176083
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.