These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

332 related articles for article (PubMed ID: 22685567)

  • 1. TRAM is involved in IL-18 signaling and functions as a sorting adaptor for MyD88.
    Ohnishi H; Tochio H; Kato Z; Kawamoto N; Kimura T; Kubota K; Yamamoto T; Funasaka T; Nakano H; Wong RW; Shirakawa M; Kondo N
    PLoS One; 2012; 7(6):e38423. PubMed ID: 22685567
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling.
    Ohnishi H; Tochio H; Kato Z; Orii KE; Li A; Kimura T; Hiroaki H; Kondo N; Shirakawa M
    Proc Natl Acad Sci U S A; 2009 Jun; 106(25):10260-5. PubMed ID: 19506249
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TRAM is required for TLR2 endosomal signaling to type I IFN induction.
    Stack J; Doyle SL; Connolly DJ; Reinert LS; O'Keeffe KM; McLoughlin RM; Paludan SR; Bowie AG
    J Immunol; 2014 Dec; 193(12):6090-102. PubMed ID: 25385819
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway.
    Yamamoto M; Sato S; Hemmi H; Uematsu S; Hoshino K; Kaisho T; Takeuchi O; Takeda K; Akira S
    Nat Immunol; 2003 Nov; 4(11):1144-50. PubMed ID: 14556004
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.
    Nagpal K; Plantinga TS; Wong J; Monks BG; Gay NJ; Netea MG; Fitzgerald KA; Golenbock DT
    J Biol Chem; 2009 Sep; 284(38):25742-8. PubMed ID: 19509286
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP.
    Andreakos E; Sacre SM; Smith C; Lundberg A; Kiriakidis S; Stonehouse T; Monaco C; Feldmann M; Foxwell BM
    Blood; 2004 Mar; 103(6):2229-37. PubMed ID: 14630816
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural complementarity of Toll/interleukin-1 receptor domains in Toll-like receptors and the adaptors Mal and MyD88.
    Dunne A; Ejdeback M; Ludidi PL; O'Neill LA; Gay NJ
    J Biol Chem; 2003 Oct; 278(42):41443-51. PubMed ID: 12888566
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of a Regulatory Acidic Motif as the Determinant of Membrane Localization of TICAM-2.
    Funami K; Matsumoto M; Enokizono Y; Ishii N; Tatematsu M; Oshiumi H; Inagaki F; Seya T
    J Immunol; 2015 Nov; 195(9):4456-65. PubMed ID: 26408662
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of Toll-interleukin 1 receptor mediated signaling.
    Li X; Qin J
    J Mol Med (Berl); 2005 Apr; 83(4):258-66. PubMed ID: 15662540
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular analysis of the binding mode of Toll/interleukin-1 receptor (TIR) domain proteins during TLR2 signaling.
    Nada M; Ohnishi H; Tochio H; Kato Z; Kimura T; Kubota K; Yamamoto T; Kamatari YO; Tsutsumi N; Shirakawa M; Kondo N
    Mol Immunol; 2012 Oct; 52(3-4):108-16. PubMed ID: 22673208
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.
    Verstak B; Nagpal K; Bottomley SP; Golenbock DT; Hertzog PJ; Mansell A
    J Biol Chem; 2009 Sep; 284(36):24192-203. PubMed ID: 19592497
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors.
    Horng T; Barton GM; Flavell RA; Medzhitov R
    Nature; 2002 Nov; 420(6913):329-33. PubMed ID: 12447442
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of binding sites for myeloid differentiation primary response gene 88 (MyD88) and Toll-like receptor 4 in MyD88 adapter-like (Mal).
    Bovijn C; Desmet AS; Uyttendaele I; Van Acker T; Tavernier J; Peelman F
    J Biol Chem; 2013 Apr; 288(17):12054-66. PubMed ID: 23460645
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry.
    Snyder GA; Deredge D; Waldhuber A; Fresquez T; Wilkins DZ; Smith PT; Durr S; Cirl C; Jiang J; Jennings W; Luchetti T; Snyder N; Sundberg EJ; Wintrode P; Miethke T; Xiao TS
    J Biol Chem; 2014 Jan; 289(2):669-79. PubMed ID: 24275656
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evolution of the TIR domain-containing adaptors in humans: swinging between constraint and adaptation.
    Fornarino S; Laval G; Barreiro LB; Manry J; Vasseur E; Quintana-Murci L
    Mol Biol Evol; 2011 Nov; 28(11):3087-97. PubMed ID: 21659570
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Heterologous Expression and Assembly of Human TLR Signaling Components in
    Coronas-Serna JM; Del Val E; Kagan JC; Molina M; Cid VJ
    Biomolecules; 2021 Nov; 11(11):. PubMed ID: 34827735
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Viral inhibitory peptide of TLR4, a peptide derived from vaccinia protein A46, specifically inhibits TLR4 by directly targeting MyD88 adaptor-like and TRIF-related adaptor molecule.
    Lysakova-Devine T; Keogh B; Harrington B; Nagpal K; Halle A; Golenbock DT; Monie T; Bowie AG
    J Immunol; 2010 Oct; 185(7):4261-71. PubMed ID: 20802145
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TIR domain-containing adaptors define the specificity of TLR signaling.
    Yamamoto M; Takeda K; Akira S
    Mol Immunol; 2004 Feb; 40(12):861-8. PubMed ID: 14698224
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Poxviral protein A46 antagonizes Toll-like receptor 4 signaling by targeting BB loop motifs in Toll-IL-1 receptor adaptor proteins to disrupt receptor:adaptor interactions.
    Stack J; Bowie AG
    J Biol Chem; 2012 Jun; 287(27):22672-82. PubMed ID: 22593572
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins.
    Watters TM; Kenny EF; O'Neill LA
    Immunol Cell Biol; 2007; 85(6):411-9. PubMed ID: 17667936
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.