These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

79 related articles for article (PubMed ID: 22686687)

  • 1. Boosting the sensitivity of ligand-protein screening by NMR of long-lived states.
    Salvi N; Buratto R; Bornet A; Ulzega S; Rentero Rebollo I; Angelini A; Heinis C; Bodenhausen G
    J Am Chem Soc; 2012 Jul; 134(27):11076-9. PubMed ID: 22686687
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Assembly of urokinase receptor-mediated plasminogen activation complexes involves direct, non-active-site interactions between urokinase and plasminogen.
    Ellis V; Whawell SA; Werner F; Deadman JJ
    Biochemistry; 1999 Jan; 38(2):651-9. PubMed ID: 9888805
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of specific sites involved in ligand binding by photoaffinity labeling of the receptor for the urokinase-type plasminogen activator. Residues located at equivalent positions in uPAR domains I and III participate in the assembly of a composite ligand-binding site.
    Ploug M
    Biochemistry; 1998 Nov; 37(47):16494-505. PubMed ID: 9843416
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Is inhibition process better described with MD(QM/MM) simulations? The case of urokinase type plasminogen activator inhibitors.
    Barbault F; Maurel F
    J Comput Chem; 2012 Mar; 33(6):607-16. PubMed ID: 22241532
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Diphenyl phosphonate inhibitors for the urokinase-type plasminogen activator: optimization of the P4 position.
    Joossens J; Van der Veken P; Surpateanu G; Lambeir AM; El-Sayed I; Ali OM; Augustyns K; Haemers A
    J Med Chem; 2006 Sep; 49(19):5785-93. PubMed ID: 16970403
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Small molecule antagonists of the urokinase (uPA): urokinase receptor (uPAR) interaction with high reported potencies show only weak effects in cell-based competition assays employing the native uPAR ligand.
    De Souza M; Matthews H; Lee JA; Ranson M; Kelso MJ
    Bioorg Med Chem; 2011 Apr; 19(8):2549-56. PubMed ID: 21454081
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ab initio molecular orbital calculations on specific interactions between urokinase-type plasminogen activator and its receptor.
    Nagase K; Kobayashi H; Yoshikawa E; Kurita N
    J Mol Graph Model; 2009 Aug; 28(1):46-53. PubMed ID: 19403319
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Photoaffinity labeling of the human receptor for urokinase-type plasminogen activator using a decapeptide antagonist. Evidence for a composite ligand-binding site and a short interdomain separation.
    Ploug M; Ostergaard S; Hansen LB; Holm A; Danø K
    Biochemistry; 1998 Mar; 37(11):3612-22. PubMed ID: 9521680
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Binding areas of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex for endocytosis receptors of the low-density lipoprotein receptor family, determined by site-directed mutagenesis.
    Skeldal S; Larsen JV; Pedersen KE; Petersen HH; Egelund R; Christensen A; Jensen JK; Gliemann J; Andreasen PA
    FEBS J; 2006 Nov; 273(22):5143-59. PubMed ID: 17042782
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular basis of specific inhibition of urokinase plasminogen activator by amiloride.
    Jankun J; Skrzypczak-Jankun E
    Cancer Biochem Biophys; 1999 Jul; 17(1-2):109-23. PubMed ID: 10738907
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural analysis of the interaction between urokinase-type plasminogen activator and its receptor: a potential target for anti-invasive cancer therapy.
    Ploug M; Gårdsvoll H; Jørgensen TJ; Lønborg Hansen L; Danø K
    Biochem Soc Trans; 2002 Apr; 30(2):177-83. PubMed ID: 12023847
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The effects of amino-acid mutations on specific interactions between urokinase-type plasminogen activator and its receptor: Ab initio molecular orbital calculations.
    Tsuji S; Kasumi T; Nagase K; Yoshikawa E; Kobayashi H; Kurita N
    J Mol Graph Model; 2011 Aug; 29(8):975-84. PubMed ID: 21605990
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Urokinase-type plasminogen activator.
    Crippa MP
    Int J Biochem Cell Biol; 2007; 39(4):690-4. PubMed ID: 17118695
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TINS, target immobilized NMR screening: an efficient and sensitive method for ligand discovery.
    Vanwetswinkel S; Heetebrij RJ; van Duynhoven J; Hollander JG; Filippov DV; Hajduk PJ; Siegal G
    Chem Biol; 2005 Feb; 12(2):207-16. PubMed ID: 15734648
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The surface of prostate carcinoma DU145 cells mediates the inhibition of urokinase-type plasminogen activator by maspin.
    McGowen R; Biliran H; Sager R; Sheng S
    Cancer Res; 2000 Sep; 60(17):4771-8. PubMed ID: 10987285
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mapping the putative binding site for uPA protein in Esophageal Cancer-Related Gene 2 by heteronuclear NMR method.
    Geng Y; Feng Y; Xie T; Dai Y; Wang J; Lu SH
    Arch Biochem Biophys; 2008 Nov; 479(2):153-7. PubMed ID: 18824154
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bicyclic peptide inhibitor reveals large contact interface with a protease target.
    Angelini A; Cendron L; Chen S; Touati J; Winter G; Zanotti G; Heinis C
    ACS Chem Biol; 2012 May; 7(5):817-21. PubMed ID: 22304751
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The construction and expression of chimeric urokinase-type plasminogen activator genes containing kringle domains of human plasminogen.
    Boutaud A; Castellino FJ
    Arch Biochem Biophys; 1993 Jun; 303(2):222-30. PubMed ID: 8512311
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cyclo19,31[D-Cys19]-uPA19-31 is a potent competitive antagonist of the interaction of urokinase-type plasminogen activator with its receptor (CD87).
    Magdolen V; Bürgle M; de Prada NA; Schmiedeberg N; Riemer C; Schroeck F; Kellermann J; Degitz K; Wilhelm OG; Schmitt M; Kessler H
    Biol Chem; 2001 Aug; 382(8):1197-205. PubMed ID: 11592401
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and evaluation of non-basic inhibitors of urokinase-type plasminogen activator (uPA).
    Venkatraj M; Messagie J; Joossens J; Lambeir AM; Haemers A; Van der Veken P; Augustyns K
    Bioorg Med Chem; 2012 Feb; 20(4):1557-68. PubMed ID: 22285569
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.