These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 22691173)

  • 1. Effect of inhibition of the ubiquitin-proteasome system and Hsp90 on growth and survival of rhabdomyosarcoma cells in vitro.
    Peron M; Bonvini P; Rosolen A
    BMC Cancer; 2012 Jun; 12():233. PubMed ID: 22691173
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Combined inhibition of Hsp90 and the proteasome affects NSCLC proteostasis and attenuates cell migration.
    Zismanov V; Drucker L; Gottfried M
    Anticancer Drugs; 2014 Oct; 25(9):998-1006. PubMed ID: 25153785
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity.
    Mimnaugh EG; Xu W; Vos M; Yuan X; Isaacs JS; Bisht KS; Gius D; Neckers L
    Mol Cancer Ther; 2004 May; 3(5):551-66. PubMed ID: 15141013
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Anti-malaria drug blocks proteotoxic stress response: anti-cancer implications.
    Neznanov N; Gorbachev AV; Neznanova L; Komarov AP; Gurova KV; Gasparian AV; Banerjee AK; Almasan A; Fairchild RL; Gudkov AV
    Cell Cycle; 2009 Dec; 8(23):3960-70. PubMed ID: 19901558
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The apoptotic effect and associated signalling of HSP90 inhibitor 17-DMAG in hepatocellular carcinoma cells.
    Leng AM; Liu T; Yang J; Cui JF; Li XH; Zhu YN; Xiong T; Zhang G; Chen Y
    Cell Biol Int; 2012 Oct; 36(10):893-9. PubMed ID: 22694478
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteasome inhibitor interacts synergistically with autophagy inhibitor to suppress proliferation and induce apoptosis in hepatocellular carcinoma.
    Hui B; Shi YH; Ding ZB; Zhou J; Gu CY; Peng YF; Yang H; Liu WR; Shi GM; Fan J
    Cancer; 2012 Nov; 118(22):5560-71. PubMed ID: 22517429
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Proteotoxic stress targeted therapy (PSTT): induction of protein misfolding enhances the antitumor effect of the proteasome inhibitor bortezomib.
    Neznanov N; Komarov AP; Neznanova L; Stanhope-Baker P; Gudkov AV
    Oncotarget; 2011 Mar; 2(3):209-21. PubMed ID: 21444945
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BAG3 induction is required to mitigate proteotoxicity via selective autophagy following inhibition of constitutive protein degradation pathways.
    Rapino F; Jung M; Fulda S
    Oncogene; 2014 Mar; 33(13):1713-24. PubMed ID: 23644654
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An autophagy inhibitor enhances the inhibition of cell proliferation induced by a proteasome inhibitor in MCF-7 cells.
    Yao F; Wang G; Wei W; Tu Y; Tong H; Sun S
    Mol Med Rep; 2012 Jan; 5(1):84-8. PubMed ID: 21931937
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Endoplasmic reticulum vacuolization and valosin-containing protein relocalization result from simultaneous hsp90 inhibition by geldanamycin and proteasome inhibition by velcade.
    Mimnaugh EG; Xu W; Vos M; Yuan X; Neckers L
    Mol Cancer Res; 2006 Sep; 4(9):667-81. PubMed ID: 16966435
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78.
    Roué G; Pérez-Galán P; Mozos A; López-Guerra M; Xargay-Torrent S; Rosich L; Saborit-Villarroya I; Normant E; Campo E; Colomer D
    Blood; 2011 Jan; 117(4):1270-9. PubMed ID: 21106982
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications.
    Spisek R; Charalambous A; Mazumder A; Vesole DH; Jagannath S; Dhodapkar MV
    Blood; 2007 Jun; 109(11):4839-45. PubMed ID: 17299090
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Efficacy of Hsp90 inhibition for induction of apoptosis and inhibition of growth in cervical carcinoma cells in vitro and in vivo.
    Schwock J; Pham NA; Cao MP; Hedley DW
    Cancer Chemother Pharmacol; 2008 Apr; 61(4):669-81. PubMed ID: 17579866
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vitro cytotoxic effect of proteasome inhibitor bortezomib in combination with purine nucleoside analogues on chronic lymphocytic leukaemia cells.
    Duechler M; Linke A; Cebula B; Shehata M; Schwarzmeier JD; Robak T; Smolewski P
    Eur J Haematol; 2005 May; 74(5):407-17. PubMed ID: 15813915
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Preventing the autophagic survival response by inhibition of calpain enhances the cytotoxic activity of bortezomib in vitro and in vivo.
    Escalante AM; McGrath RT; Karolak MR; Dorr RT; Lynch RM; Landowski TH
    Cancer Chemother Pharmacol; 2013 Jun; 71(6):1567-76. PubMed ID: 23572175
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Blocking autophagy prevents bortezomib-induced NF-κB activation by reducing I-κBα degradation in lymphoma cells.
    Jia L; Gopinathan G; Sukumar JT; Gribben JG
    PLoS One; 2012; 7(2):e32584. PubMed ID: 22393418
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pim-1 kinase stability is regulated by heat shock proteins and the ubiquitin-proteasome pathway.
    Shay KP; Wang Z; Xing PX; McKenzie IF; Magnuson NS
    Mol Cancer Res; 2005 Mar; 3(3):170-81. PubMed ID: 15798097
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 17-DMAG induces heat shock protein 90 functional impairment in human bladder cancer cells: knocking down the hallmark traits of malignancy.
    Karkoulis PK; Stravopodis DJ; Voutsinas GE
    Tumour Biol; 2016 May; 37(5):6861-73. PubMed ID: 26662567
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bortezomib/proteasome inhibitor triggers both apoptosis and autophagy-dependent pathways in melanoma cells.
    Selimovic D; Porzig BB; El-Khattouti A; Badura HE; Ahmad M; Ghanjati F; Santourlidis S; Haikel Y; Hassan M
    Cell Signal; 2013 Jan; 25(1):308-18. PubMed ID: 23079083
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Schwann cell autophagy induced by SAHA, 17-AAG, or clonazepam can reduce bortezomib-induced peripheral neuropathy.
    Watanabe T; Nagase K; Chosa M; Tobinai K
    Br J Cancer; 2010 Nov; 103(10):1580-7. PubMed ID: 20959823
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.